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API-2

API-2
API-2
CAS No.
35943-35-2
Chemical Name:
API-2
Synonyms
TCN;IAP1;MIHC;MYHL;BBMI;API-2;BIRC3;RNF49;MYO1A;nosyl-
CBNumber:
CB3270000
Molecular Formula:
C13H16N6O4
Formula Weight:
320.3
MOL File:
35943-35-2.mol

API-2 Properties

storage temp. 
Store at RT
solubility 
DMSO: >10mg/mL
color 
tan

SAFETY

RTECS  RY8455000

API-2 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T3830 Triciribine hydrate ≥97% (HPLC) 35943-35-2 5mg $200 2017-11-08 Buy
Sigma-Aldrich 124038 InSolution? Akt Inhibitor V, Triciribine 35943-35-2 2mg $246 2017-11-08 Buy
Sigma-Aldrich T3830 Triciribine hydrate ≥97% (HPLC) 35943-35-2 25mg $822 2017-11-08 Buy

API-2 Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Triciribine is an antitumor tricyclic nucleoside. Triciribine acts as a potent, small-molecule inhibitor of AKT phosphorylation in subjects with solid tumors contining activated AKT. Triciribine is al so a selective inhibitor of HIV-1 and HIV-2, including strains known to be resistant to AZT or TIBO.

Biological Activity

Selective inhibitor of Akt (protein kinase B) signaling; displays minimal inhibition of PKC, PKA, SGK and p38 pathways. Inhibits phosphorylation and activation of downstream targets of Akt including Bad, GSK-3 β and AFX. In vitro, induces apoptosis and growth arrest preferentially in human cancer cells with elevated levels of Akt. In mice, potently and selectively inhibits growth of Akt-overexpressing tumors. Inhibits DNA synthesis and displays antiviral activity against HIV-1 and -2.

API-2 Preparation Products And Raw materials

Raw materials

Preparation Products


API-2 Suppliers

Global( 55)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Wuhan HengHeDa Pharm Co., Ltd. 027-84888681 Mobile:18086046872
027-84888682 hhdpharm@hotmail.com QQ: 2461625847 China 1910 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96820 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15940 69
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32527 50
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811783;
+86 (531) 55696010 QQ 1762738062 sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) China 1810 62
Wuhan Vanzpharm Inc. +86-027-84492310, +86-18502744322
+86-027-84492310 lansky@vanzpharm.com, QQ1009531590 China 167 58
BOC Sciences
info@bocsci.com United States 10073 65
Dalian Meilun Biotech Co., Ltd. 0411-66771943;0411-66771942
0411-66771945 sales@meilune.com China 4801 58
T&W GROUP +86-21-61551611, 61551462, 61551420, 61551610
+86-21-50676805 contact@trustwe.com China 13365 58
NCE Biomedical Co.,Ltd. 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988
+86-27-87599188 sales@ncebiomed.com China 1500 55

35943-35-2(API-2)Related Search:


  • API-2
  • 35943-35-2
  • 6-AMINO-4-METHYL-8-(BETA-D-RIBOFURANOSYL)-4H,8H-PYRROLO[4,3,2-DE]PYRIMIDO[4,5-C]PYRIDAZINE
  • AKT/PKB SIGNALING INHIBITOR-2
  • AKT INHIBITOR V
  • 1,5-DIHYDRO-5-METHYL-1-BETA-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-3-AMINE
  • 1,4,5,6,8-pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-d-ribofura
  • 1,4,5,6,8-pentaazaacenaphthylene,3-amino-1,5-dihydro-5-methyl-1-beta-d-ribof
  • 3-amine
  • 3-amino-1,5-dihydro-5-methyl-1-beta-d-ribofuranosyl-1,4,5,6,8-pentaazaacenap
  • 4,5,6,8-pentaazaacenaphthylen-5-dihydro-5-methyl-1-beta-d-ribofuranosyl-1
  • hthylene
  • nosyl-
  • pentaazacentopthylene
  • uranosyl-
  • TRICYCLIC NUCLEOSIDE
  • TRICIRIBINE
  • NSC 154020
  • TCN
  • API-2 (Tricirbine)
  • Protein Kinase
  • 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine
  • (1,4,5,6,8-Pentaazaacenaphthylen-3-aMine,1,5-dihydro-5-Methyl-1-b-D-ribofuranosyl-)
  • 6-AMino-4-Methyl-8-(β-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyriMido[4,5-c]pyridazine
  • (2R,3R,4S,5R)-2-(3-aMino-5-Methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
  • VD-0002
  • 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine Triciribine
  • Triciribine 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine
  • Inhibitor V
  • Triciribine hydrate
  • ANTI-CIAP2 (BIRC3)(N-TERMINAL) antibody produced in rabbit
  • BIRC3
  • IAP1
  • MIHC
  • RNF49
  • ANTI-MYO1A (CENTER S291) antibody produced in rabbit
  • Brush border myosin I
  • MYHL
  • Myosin-Ia
  • Anti-MYO1A antibody produced in rabbit
  • BBMI
  • DFNA48
  • MYO1A
  • Anti-Dfna48
  • Anti-Myhl
  • Anti-Myosin ia
  • Triciribine, >=98%
  • Inhibitors
  • (1R,2S,3R,5R)-3-(3-Amino-5-methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxymethyl)c
  • InSolution? Akt Inhibitor V, Triciribine
  • Akt
  • mTOR
  • PI3K
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