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API-2

CAS No.35943-35-2
Chemical Name:API-2
Synonyms:TCN;API-2;nosyl-;3-amine;hthylene;uranosyl-;NSC 154020;TRICIRIBINE;AKT INHIBITOR V;API-2 (Tricirbine)
CBNumber:CB3270000
Molecular Formula:C13H16N6O4
Formula Weight:320.3
MOL File:35943-35-2.mol
API-2 Property
storage temp. : Store at RT
Safety

API-2 Chemical Properties,Usage,Production

Biological Activity
Selective inhibitor of Akt (protein kinase B) signaling; displays minimal inhibition of PKC, PKA, SGK and p38 pathways. Inhibits phosphorylation and activation of downstream targets of Akt including Bad, GSK-3 β and AFX. In vitro, induces apoptosis and growth arrest preferentially in human cancer cells with elevated levels of Akt. In mice, potently and selectively inhibits growth of Akt-overexpressing tumors. Inhibits DNA synthesis and displays antiviral activity against HIV-1 and -2.
API-2 Preparation Products And Raw materials
Raw materials
Preparation Products
API-2 Suppliers      Global( 28)Suppliers     
SupplierTelFaxEmailCountryProdListAdvantage
Wuhan Vanzpharm Inc. +86-027-84254882, 18502744322+86-027-84254881vanzpharm@hotmail.comCHINA 954 58
Wuhan HengHeDa Pharm Co., Ltd. 027-84888681027-84888682hhdpharm@hotmail.comCHINA 1870 55
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、803、804、807 Mobile:1893055203786-21-50328109shanghai@3bsc.comCHINA 15991 69
Chemsky (shanghai) International Co.,Ltd 021-50135380 chemsky@live.comCHINA 36790 60
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811783;+86 (531) 88806178;+(0)13153010282;+(0)13153192680+86 (531) 55696010sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)CHINA 1680 62
ShangHai Biochempartner Co.,Ltd +86 13818785766,400-021-9906 gaoqing@biochempartner.comCHINA 1171 62
Wuhan Sunrise Technology Development Co., Ltd. +86 (27) 8331-4682 / +86 13554138826+86 (27) 8331-4682whsrtech@vip.163.com,whsrtech@whsrtech.comCHINA 300 62
NCE Biomedical Co.,Ltd. 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988+86-27-87599188sales@ncebiomed.comCHINA 1279 55
Shanghai Haoyuan Chemexpress Co., Ltd +86-21-58955995, 51870955+86-21-53700326sales@chemexpress.com.cnCHINA 10000 61
shanghai cooperpharm co.,LTD . +86-021-58975553+86-021-58975554sales@cooperpharm.comCHINA 1210 56
 
35943-35-2(API-2)Related Search:
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API-2 35943-35-2 6-AMINO-4-METHYL-8-(BETA-D-RIBOFURANOSYL)-4H,8H-PYRROLO[4,3,2-DE]PYRIMIDO[4,5-C]PYRIDAZINE AKT/PKB SIGNALING INHIBITOR-2 AKT INHIBITOR V 1,5-DIHYDRO-5-METHYL-1-BETA-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-3-AMINE 1,4,5,6,8-pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-d-ribofura 1,4,5,6,8-pentaazaacenaphthylene,3-amino-1,5-dihydro-5-methyl-1-beta-d-ribof 3-amine 3-amino-1,5-dihydro-5-methyl-1-beta-d-ribofuranosyl-1,4,5,6,8-pentaazaacenap 4,5,6,8-pentaazaacenaphthylen-5-dihydro-5-methyl-1-beta-d-ribofuranosyl-1 hthylene nosyl- pentaazacentopthylene uranosyl- TRICYCLIC NUCLEOSIDE TRICIRIBINE NSC 154020 TCN API-2 (Tricirbine) Protein Kinase 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine (1,4,5,6,8-Pentaazaacenaphthylen-3-aMine,1,5-dihydro-5-Methyl-1-b-D-ribofuranosyl-) 6-AMino-4-Methyl-8-(β-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyriMido[4,5-c]pyridazine (2R,3R,4S,5R)-2-(3-aMino-5-Methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
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