ChemicalBook >> CAS DataBase List >>(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid

CAS No.
1012341-48-8
Chemical Name:
(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid
Synonyms
E)-5-([1;LCZ-696-013;LCZ696 impurities2;LCZ-696 Impurity 58;LCZ696 impurities114;LCZ696 Intermediate II;(R,E)-5-([1,1'-BiphenyL;Sacubitril intermediates;)-4-((tert-butoxycarbonyL;LCZ696(valsartan + sacubitril) impurity 30
CBNumber:
CB32723687
Molecular Formula:
C23H27NO4
Molecular Weight:
381.46
MDL Number:
MFCD28386950
MOL File:
1012341-48-8.mol
MSDS File:
SDS
Last updated:2023-08-30 16:29:03

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid Properties

Melting point 188 - 191°C
Boiling point 595.6±50.0 °C(Predicted)
Density 1.132±0.06 g/cm3(Predicted)
vapor pressure 8.4-839.931Pa at 20℃
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 4.67±0.19(Predicted)
form Solid
color White to Off-White
InChI InChI=1S/C23H27NO4/c1-16(21(25)26)14-20(24-22(27)28-23(2,3)4)15-17-10-12-19(13-11-17)18-8-6-5-7-9-18/h5-14,20H,15H2,1-4H3,(H,24,27)(H,25,26)/b16-14+/t20-/m0/s1
InChIKey JXTNUXJSXXIIFE-VISDOYDDSA-N
SMILES C(O)(=O)/C(/C)=C/[C@H](NC(OC(C)(C)C)=O)CC1=CC=C(C2=CC=CC=C2)C=C1
LogP 2.2-3.6 at 25℃ and pH2.5-7

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M345205 (R,E)-5-([1,1-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoicAcid 1012341-48-8 5g $90 2021-12-16 Buy
AK Scientific 1698DN (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoicacid 1012341-48-8 5g $93 2021-12-16 Buy
AK Scientific 1698DN (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoicacid 1012341-48-8 25g $176 2021-12-16 Buy
Crysdot CD12187609 (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoicacid 97% 1012341-48-8 100g $218 2021-12-16 Buy
Chemenu CM244547 (R,E)-5-([1,1''-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoicacid 95+% 1012341-48-8 1000g $1440 2021-12-16 Buy
Product number Packaging Price Buy
M345205 5g $90 Buy
1698DN 5g $93 Buy
1698DN 25g $176 Buy
CD12187609 100g $218 Buy
CM244547 1000g $1440 Buy

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid Chemical Properties,Uses,Production

Uses

(R,E)-5-([1,1-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-methylpent-2-enoic Acid is used in preparation of sacubitril intermediate using Nickel Salt catalyst.

149709-59-1
1012341-48-8
Synthesis of (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid from (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 205)Suppliers
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ChemExpress
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Hangzhou ICH Biofarm Co., Ltd
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ATK CHEMICAL COMPANY LIMITED
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View Lastest Price from (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid pictures 2023-11-01 (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid
1012341-48-8
US $0.00-0.00 / kg 1kg 99% 500KG Hangzhou ICH Biofarm Co., Ltd
	(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid pictures 2020-01-17 (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid
1012341-48-8
US $1.00 / KG 1KG 85.0-99.8% 200kgs Career Henan Chemical Co
(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid pictures 2020-01-03 (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid
1012341-48-8
US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co
(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid (2E,4R)-5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-Pentenoic acid 5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-2-enoic acid 2-Pentenoic acid, 5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-, (2E,4R)- (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid###1012341-48-8 enantioMer (R,E)-5-(biphenyl-4-yl)-4-(tert-butoxycarbonylamino)-2-methylpent-2-enoic acid (R,E)-5-(biphenyl-4-yl)-4-(tert-butoxycarbonylamino) (2E,4R)-5-[1,1'-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic acid AHU83 1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid E)-5-([1 (R, E) -5-([1,1'-Biphenyl] -4-yl) -4-((tert-butoxycarbonyl) amino) -2-methyl-2-pentenoic acid LCZ696(valsartan + sacubitril) impurity 30 (2E,4R)-5-{[1,1'-biphenyl]-4-yl}-4-{[(tert-butoxy)carbonyl]amino}-2-methylpent-2-enoic acid (R,E)-5-([1,1'-BiphenyL )-4-((tert-butoxycarbonyL LCZ696 intermediates,(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert- butoxycarbonyl)aMino)-2-Methylpent- 2-enoic acid (E,4r)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pent-2-enoic acid (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid (LCZ696 Impurity) (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino... LCZ696 impurities114 LCZ696 impurities2 (R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-(E)-2-enoic acidQ: What is (R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-(E)-2-enoic acid Q: What is the CAS Number of (R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-(E)-2-enoic acid Q: What is the storage condition of (R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-(E)-2-enoic acid Q: What are the applications of (R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-(E)-2-enoic acid LCZ-696 Impurity 58 2-Amino-4-(4-fluorbenzylamino)-3-ethoxycarbonylaminobenzene (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid LCZ-696-013 (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoicaci LCZ696 Intermediate II Sacubitril intermediates 1012341-48-8 1212341-48-8 LCZ696 intermediate intermediates 1012341-48-8