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LANATOSIDE C

CAS No.
17575-22-3
Chemical Name:
LANATOSIDE C
Synonyms
Allocor;Celanid;Ceglunat;isolanid;Celanide;NSC 7533;isolanide;cedilanid;Ceglunate;Celadigal
CBNumber:
CB3298279
Molecular Formula:
C49H76O20
Molecular Weight:
985.12
MDL Number:
MFCD00869432
MOL File:
17575-22-3.mol
MSDS File:
SDS
Last updated:2023-08-25 11:46:16

LANATOSIDE C Properties

Melting point 272-274°C
alpha D20 +33.4 to +33.7° (200 mg dry weight in 10 ml alcohol)
Boiling point 741.7°C (rough estimate)
Density 1.42±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 1.7630 (estimate)
storage temp. -20°C
solubility DMSO:50.0(Max Conc. mg/mL);50.75(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);2.03(Max Conc. mM)
pka 12.89±0.70(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
LogP 0.070
EWG's Food Scores 1
FDA UNII 5RR3JFZ771
ATC code C01AA06

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H330-H373
Precautionary statements  P260-P264-P270-P271-P304+P340+P310-P314
Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  OE2100000

LANATOSIDE C price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L2261 Lanatoside C ≥95% 17575-22-3 100mg $145 2024-03-01 Buy
Sigma-Aldrich L2261 Lanatoside C ≥95% 17575-22-3 1g $844 2024-03-01 Buy
TRC L173800 Lanatoside C 17575-22-3 100mg $410 2021-12-16 Buy
TRC L173800 Lanatoside C 17575-22-3 1mg $60 2021-12-16 Buy
Usbiological 297329 Lanatoside C 17575-22-3 100mg $375 2021-12-16 Buy
Product number Packaging Price Buy
L2261 100mg $145 Buy
L2261 1g $844 Buy
L173800 100mg $410 Buy
L173800 1mg $60 Buy
297329 100mg $375 Buy

LANATOSIDE C Chemical Properties,Uses,Production

Chemical Properties

White Solid

Originator

Lanatozid C,Biofarm

Uses

anti-acne

Uses

Glycosides

Manufacturing Process

2000 parts of dry leaves of digitalis lanata are finely ground with 500 parts of sodium chloride, they are then wetted with 1000 parts of water and extracted with 30,000 parts of chloroform. The filtered extract is completely evaporated in vacuum at a low temperature and to the remaining residue are added 1000 parts of dry ether and the whole mixture is left under the ether until the thick viscous mass has been transformed into a hard body. The ether is then poured away and the residue is digested with 1000 parts of ether for about 2 hours under a reflux condenser. After cooling down the mixture, it is filtered, and the residue obtained, which is now in form of a brittle mass, which is then dried in vacuum in order to completely eliminate the remaining ether present, and pulverized. The pulverized mass is advantageously subjected once more to the treatment with ether. The yellow greenish powder thus obtained is then dissolved in 1000 parts of methyl alcohol and to the solution, so obtained a fine suspension of 30 parts lead hydroxide in 1000 parts water is added with stirring. The solution obtained is neutralized, stirred for about 2 hours, andfiltered, and the clear yellowish filtrate is preferably treated again with a small quantity of tannin precipitating substance. The clear filtrate thus obtained is concentrated in vacuum at a low temperature to about 200 parts, whereby the difficultly soluble portion of the glucoside mixture precipitates. The solution is then filtered. The precipitate is dissolved in a small quantity of methyl alcohol and is treated with a small quantity of water whereby the new product begins to precipitate in a crystalline form. By repeated crystallization from methyl alcohol, without addition of water, the glucoside may be obtained in the form of a perfectly pure compound; it does not change its properties even on further recrystallization. The glucoside, freshly crystallized from methyl alcohol and dried in vacuo, had MP: 248°C with decomposition, when heated rapidly. At 230°-235°C, the substance begins to sinter and becomes quite soft; the melting point, therefore, is not well defined.

Therapeutic Function

Cardiotonic

Purification Methods

Crystallise lanatoside C from MeOH. Its solubility is : 1/17000 (H2O), 1/45 (EtOH) and 1/1500-2000 (CHCl3). [Stoll et al. Helv Chim Acta 16 1049 1933, Stoll & Kreis Helv Chim Acta 35 1318 1952, Okada et al. Chem Pharm Bull Jpn 23 2039 1975, Beilstein 18 III/IV 2455.] It is cardiotonic.

LANATOSIDE C Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 177)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10326 58

View Lastest Price from LANATOSIDE C manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LANATOSIDE C pictures 2024-04-12 LANATOSIDE C
17575-22-3
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
Lanatoside C pictures 2023-02-24 Lanatoside C
17575-22-3
US $0.00 / mg 20mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
LANATOSIDE C USP/EP/BP pictures 2021-08-10 LANATOSIDE C USP/EP/BP
17575-22-3
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
  • LANATOSIDE C pictures
  • LANATOSIDE C
    17575-22-3
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • Lanatoside C pictures
  • Lanatoside C
    17575-22-3
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
LANATOSIDE C 20(22),5BETA-CARDENOLID-3BETA,12BETA,14BETA-TRIOL 3BETA-O-BETA-D-GLUCOPYRANOSYL-(1->4)-O-BETA-D-[3-O-ACETYLDIGITOXOPYRANOSYL]-(1->4)-O-BETA-D-DIGITOXOPYRANOSIDE-(1->4)-O-BETA-D-DIGITOXOPYRANOSIDE Lanatoside C (Digoxin Impurity H) cedilanid digilanidc digilanidec isolanid isolanide Allocor Card-20(22)-enolide, 3-[(O-b-D-glucopyranosyl-(14)-O-3-O-acetyl-2,6-dideoxy-b-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-b-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3b,5b,12b)- (9CI) Ceglunat Ceglunate Celadigal Celanid Celanide Cetosanol Digilanogen C Lanatigen C Lanimerck NSC 119991 NSC 7533 Lanatosid C LANATOSIDE C 97% LANATOSIDE C WHO(CRM STANDARD) LANATOSIDE C(REAGENT / STANDARD GRADE) Card-20(22)-enolide, 3-[(o-.beta.-D-glucopyranosyl-(1.fwdarw.4)-o-3-o-acetyl-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1.fwdarw.4)-o-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1.fwdarw.4)-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3.beta.,5.beta.,12.beta.)- (3β,5β,12β)- Digoxin EP Impurity H Digoxin Impurity 8(Digoxin EP Impurity H) Trigonin C (digoxin impurity H) Digoxin EP Impurity H (Lanatoside C) Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)- LANATOSIDE C USP/EP/BP (2R,3R,4S,6S)-6-(((2R,3S,4S,6S)-6-(((2R,3S,4S,6R)-6-(((3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-2-methyl-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl acetate Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)- 3β-[(β-D-glucopyranosyl-(1→4)-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12β,14-dihydroxy-5β-card-20(22)-enolide (lanatoside C), 17575-22-3 C49H76O20 Biochemicals and Reagents BioChemical Carbohydrates Oligosaccharide Cardioglycosides & Glycosides Carbohydrates Carbohydrates A to Carbohydrates H-LBiochemicals and Reagents Oligosaccharide Intermediates & Fine Chemicals Oligosaccharides Pharmaceuticals Steroids DIFFERIN