Selank peptide
- CAS No.
- 129954-34-3
- Chemical Name:
- Selank peptide
- Synonyms
- SLANK;Selanc;SELANK;PL14736;Selank CAS;Salbu Sulfate;Selank peptid;SelankAcetate;Selank peptide;Peptides Selank Injection
- CBNumber:
- CB33161651
- Molecular Formula:
- C33H57N11O9
- Molecular Weight:
- 751.87
- MDL Number:
- MFCD11840762
- MOL File:
- 129954-34-3.mol
| Melting point | 134-136 °C |
|---|---|
| Density | 1.53±0.1 g/cm3(Predicted) |
| pka | 3.43±0.20(Predicted) |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| InChIKey | JTDTXGMXNXBGBZ-YVHUGQOKSA-N |
| SMILES | C(O)(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](O)C)N |
| FDA UNII | TS9JR8EP1G |
Selank peptide price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27720 | Selank (acetate) | 129954-34-3 | 5mg | $508 | 2023-01-06 | Buy |
| Cayman Chemical | 27720 | Selank (acetate) | 129954-34-3 | 10mg | $879 | 2023-01-06 | Buy |
| Cayman Chemical | 27720 | Selank (acetate) | 129954-34-3 | 1mg | $136 | 2023-01-06 | Buy |
Selank peptide Chemical Properties,Uses,Production
Description
Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg.
Uses
Selank peptide has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species. It is often prescribed for its anxiolytic properties, immune improvement, gastric protection, and with opioid and alcohol withdrawal/ dependence. It also has a nootropic action, which positively influences the formation of memory and learning processes, and marked immunomodulatory activity.
Mechanism of action
It is known that the classical benzodiazepines act via gamma-aminobutyric acid (GABA) type A receptors. They enhance the GABA effect by allosteric modulation, which increases the frequency of opening of channels for chlorine ions. The Selank action mechanism may be related to its ability to affect the performance of the GABAergic system.
Selank peptide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 | honestchemical@foxmail.com | China | 247 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Wuhan Marco Pharmaceutical Technology Co., Ltd. | +86-86-18572802410 +8618572802410 | sales@marcopht.com | China | 55 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 305 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
| Hebei Xunou new energy Technology Co., LTD | +undefined17531957005 | xunou8@hbxunou.com | China | 36 | 58 |
| Shanghai Chinqesen Biotechnology Co., Ltd. | +86-16628886292 +86-19521323435 | sales2@qschem-pharma.com | China | 46 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
View Lastest Price from Selank peptide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-25 | Selank peptide
129954-34-3
|
US $1.00 / g | 1g | 99% | 100kg | Dorne Chemical Technology co. LTD | |
 |
2024-04-25 | selank peptide | US $35.00 / box | 1box | >99% | 20tons | Hong Kong Excellence Biotechnology Co., Ltd. | |
 |
2024-04-25 | Selank
129954-34-3
|
US $60.00-40.00 / box | 2box | 99% | 100000kg | Hebei Kangcang new material Technology Co., LTD |
-
- Selank peptide
129954-34-3
- US $1.00 / g
- 99%
- Dorne Chemical Technology co. LTD
-
- selank peptide
- US $35.00 / box
- >99%
- Hong Kong Excellence Biotechnology Co., Ltd.
-
- Selank
129954-34-3
- US $60.00-40.00 / box
- 99%
- Hebei Kangcang new material Technology Co., LTD