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DIGITONIN

CAS No.
11024-24-1
Chemical Name:
DIGITONIN
Synonyms
itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONIN TECH
CBNumber:
CB3331307
Molecular Formula:
C56H92O29
Molecular Weight:
1229.31
MDL Number:
MFCD00077729
MOL File:
11024-24-1.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:14

DIGITONIN Properties

Melting point 230-240 °C (dec.)(lit.)
Boiling point 788.4°C (rough estimate)
alpha D20 -54° (0.45 g in 15.8 ml methanol)
Density 1.1421 (rough estimate)
refractive index -52 ° (C=1, EtOH)
storage temp. Sealed in dry,Room Temperature
solubility H2O: 10 mg/mL at 95 °C hot, clear, colorless
form White powder
pka 12.68±0.70(Predicted)
color white
optical activity [α]20/D 54°, c = 2.8 in methanol(lit.)
Merck 14,3161
BRN 78654
Stability Hygroscopic
InChIKey FAAZZWIYYDUONB-JYIJKGCVSA-N
EWG's Food Scores 1
FDA UNII KOO5CM684H
EPA Substance Registry System Digitonin (11024-24-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H373
Precautionary statements  P301+P310+P330-P314
Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  22-28-36/37-45
RIDADR  UN 3462 6.1/PG 3
WGK Germany  3
RTECS  IH2050050
3-10
HazardClass  6.1(a)
PackingGroup  II
HS Code  29389090
NFPA 704
0
4 0

DIGITONIN price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D141 Digitonin Used as non-ionic detergent 11024-24-1 100mg $82 2024-03-01 Buy
Sigma-Aldrich D141 Digitonin Used as non-ionic detergent 11024-24-1 500mg $276 2024-03-01 Buy
TCI Chemical D0540 Digitonin 11024-24-1 100mg $95 2024-03-01 Buy
Cayman Chemical 14952 Digitonin 11024-24-1 100mg $68 2024-03-01 Buy
Cayman Chemical 14952 Digitonin 11024-24-1 1g $435 2024-03-01 Buy
Product number Packaging Price Buy
D141 100mg $82 Buy
D141 500mg $276 Buy
D0540 100mg $95 Buy
14952 100mg $68 Buy
14952 1g $435 Buy

DIGITONIN Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

Natural surfactant useful for receptor solubilization and cell permeabilization, e.g., blood platelets, hepatocytes, yeast or tumor cells

Uses

enhances membrane permeability

Uses

Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.

Uses

Clinical reagent (cholesterol determination).

General Description

Crystals or white powder.

Air & Water Reactions

Forms soapy aqueous suspension .

Reactivity Profile

DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992

Fire Hazard

Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]

DIGITONIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 290)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Pioneer Biotech Co., Ltd .
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Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
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Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58

View Lastest Price from DIGITONIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Digitonin pictures 2023-02-13 Digitonin
11024-24-1
US $80.00 / kg 1kg 99% 100MT Hebei baicao biology science and technology co., ltd
DIGITONIN pictures 2019-07-06 DIGITONIN
11024-24-1
US $1.00 / KG 1KG 98% 1 Career Henan Chemical Co
  • Digitonin pictures
  • Digitonin
    11024-24-1
  • US $80.00 / kg
  • 99%
  • Hebei baicao biology science and technology co., ltd
  • DIGITONIN pictures
  • DIGITONIN
    11024-24-1
  • US $1.00 / KG
  • 98%
  • Career Henan Chemical Co
25R,5ALPHA-SPIROSTAN-2ALPHA,3BETA,15BETA-TRIOL 3BETA-O-BETA-D-GALACTOPYRANOSYL-(1->3)-O-BETA-D-GALACTYOPYRANOSYL-(1->2)-O-BETA-D-[3-O-BETA-D-XYLOPYRANOSYL]-(1->4)-O-BETA-D-GALACTOPYRANOSIDE DIGITONIN CRYSTALLINE Digitonin, High Purity DIGITONIN (DIGITIN) HIGH PURITY RECEPTOR SOLUBILIZING DigitoninGr Digitonin, AR DIGITONIN, USED AS NON-IONIC DETERGE beta.-D-Galactopyranoside, (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1?3)-O-.beta.-D-galactopyranosyl-(1?2)-O-.beta.-D-xylopyranosyl-(1?3)-O-.beta.-D-glucopyranosyl-(1?4)- (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1 .beta.-D-Galactopyranoside DIGITONIN TECH DIGITONIN,CRYSTAL,REAGENT DIGITONIN(RG) (1→3)]-O-β-D-glucopyranosyl-(1→4)- β-D- (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-ylO-.beta.-D-glucopyranosyl-(1.beta.-D-Galactopyranoside beta-d-galactopyranoside,(2alpha,3beta,5alpha,15beta,25theta)-2,15-dihyd osyl-(1.fwdarw.2)-o-[beta-d-xylopyranosyl-(1.fwdarw.3)]-o-beta-d-glucopyranos roxyspirostan-3-ylo-beta-d-glucopyranosyl-(1.fwdarw.3)-o-beta-d-galactopyran yl-(1.fwdarw.4)- Digitonin ,50% 2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl-O-β-D-glucopyranosyl-1β-D-Galactopyranoside DIGITIN DIGITONIN DIGITONIN, ALCOHOL-SOLUBLE DIGITONIN WATER SOLUBLE Digitogenin,3-[O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl- galactopyranoside] Digitonin, approx. 50% (TLC) [(25R)-2α,15β-Dihydroxy-5α-spirostan-3β-yl]4-O-[2-O-[3-O-(β-D-glucopyranosyl)-β-D-galactopyranosyl]-3-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]-β-D-galactopyranoside Digitonin, approx. 50% (TLC) 500MG Digitonin, approx. 50% (TLC) 5GR DIGITONINANALYTICAL GRADE DIGITONIN WATER SOLUBLERESEARCH GRADE Digitonin,Digitin Digitonin, approx. 50%, water soluble 5% Digitonin Digitonin USP itonin β-D-Galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)- Digitonin (Digitin) extrapure, 50% 3-Benzoxazole-6-carboxylic acid igitonin Digitonin (8CI) 11024-24-1 C56H92O29 C56H92O28 Sterols Lipids Non-Ionic Detergents Conjugates Biochemicals and Reagents BioChemical Surfactants (for Biochemistry) Sugars Nonionic Surfactants (for Biochemistry) Glycosides Steroids Steroidglycosides