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Fmoc-Trp(Boc)-OH

Fmoc-Trp(Boc)-OH structure

CAS No.: 143824-78-6

Chemical Name:: Fmoc-Trp(Boc)-OH

Synonyms: FMOC-L-TRP(BOC)-OH;FMOC-TRP(BOC);FMOC-L-TRP(BOC);N1-Boc-NaL;pha-Fmoc-L;FMOC-TRP(BOC)-OH;Fomc-Trp(Boc)-OH;Fmoc-Trp(Boc)-0H;FMOC-L-TRYPTOPHANE;FMOC-L-TRP(TBOC)-OH

CBNumber:: CB3360314

Molecular Formula:: C31H30N2O6

Molecular Weight:: 526.58

MDL Number:: MFCD00153366

MOL File:: 143824-78-6.mol

MSDS File:: SDS

Last updated:2024-04-16 18:29:06

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Fmoc-Trp(Boc)-OH Properties

Melting point	ca 97℃
alpha	-21 º (c=1%, DMF)
Density	1.28±0.1 g/cm3(Predicted)
refractive index	-20 ° (C=1, DMF)
storage temp.	2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Solid
pka	3.71±0.10(Predicted)
color	White to Orange to Green
optical activity	[α]20/D 21±2°, c = 1% in DMF
Sensitive	Moisture Sensitive
BRN	7698009
InChIKey	ADOHASQZJSJZBT-SANMLTNESA-N
CAS DataBase Reference	143824-78-6(CAS DataBase Reference)
FDA UNII	X3V4CFM5R8

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H317-H401-H411

Precautionary statements

P261-P280g-P302+P352a-P321-P333+P313-P501a

Hazard Codes

Xi,N

Risk Statements

36/37/38-51/53-43

Safety Statements

22-24/25-36/37/39-27-26-61-37-24

RIDADR

3077

WGK Germany

10-21

HazardClass

HS Code

29339900

NFPA 704

	1
2		0

Fmoc-Trp(Boc)-OH price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.52050	Fmoc-Trp(Boc)-OH Novabiochem?	143824-78-6	25g	$196	2024-03-01	Buy
Sigma-Aldrich	8.52050	Fmoc-Trp(Boc)-OH Novabiochem?	143824-78-6	100g	$511	2024-03-01	Buy
Sigma-Aldrich	8.52050	Fmoc-Trp(Boc)-OH Novabiochem?	143824-78-6	250g	$1090	2024-03-01	Buy
Sigma-Aldrich	8.52050	Fmoc-Trp(Boc)-OH Novabiochem?	143824-78-6	1kg	$4080	2024-03-01	Buy
Sigma-Aldrich	47561	Fmoc-Trp(Boc)-OH ≥97.0% (HPLC)	143824-78-6	5G	$71.2	2024-03-01	Buy

Product number	Packaging	Price	Buy
8.52050	25g	$196	Buy
8.52050	100g	$511	Buy
8.52050	250g	$1090	Buy
8.52050	1kg	$4080	Buy
47561	5G	$71.2	Buy

Fmoc-Trp(Boc)-OH Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

Fmoc-Trp(Boc)-OH can be used for the synthesis of analogs of glucagon-like peptide-1 (GLP-1) for the treatment of type 2 diabetes and various peptides by Fmoc solid phase peptide synthesis (SPPS).

Uses

Fmoc-Trp(Boc)-OH is a very useful synthetic intermediate. It is used to prepare Trp containing-peptides.

General Description

The use of this N-in-Boc protected derivative overcomes most of the problems associated with the preparation of Trp containing-peptides by Fmoc SPPS [1]. Cleavage with TFA generates an N-in-carboxy indole which protects the Trp from alkylation [1, 2, 3] and sulfonation [1, 4, 5, 6, 7]. The N-in-carboxy group is removed under aqueous conditions during normal work-up of the peptide.

The product number for this product was previously 04-12-1103.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Fmoc-Trp(Boc)-OH synthesis

Synthesis of Fmoc-Trp(Boc)-OH from tert-butyl 3-[(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-methoxy-3-oxopropyl]indole-1-carboxylate

Fmoc-Trp(Boc)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

L-Phe-D-Trp-OH Fmoc-β-HomoTrp(Boc)-OH

Fmoc-Trp(Boc)-OH Suppliers

Global( 451)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1472	58
Wuhan senwayer century chemical Co.,Ltd	+undefined-27-86652399 +undefined13627115097	market02@senwayer.com	China	874	58
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-028-64841719 +8618980456393	daisy@enlaibio.com	China	1369	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7534	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9350	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60

Supplier	Advantage
Chemtour Biotech Co., Ltd	58
Wuhan senwayer century chemical Co.,Ltd	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60

View Lastest Price from Fmoc-Trp(Boc)-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-23	Fmoc-Trp(Boc)-OH 143824-78-6	US $0.00-0.00 / kg	1kg	98%	1T	Sichuan HongRi Pharma-Tech Co.,Ltd
2024-04-23	Fmoc-Trp(Boc)-OH 143824-78-6	US $5.00 / kg	1kg	≥99%	100mt/year	Jinan Finer Chemical Co., Ltd
2024-04-16	Fmoc-Trp(Boc)-OH 143824-78-6	US $3.00-1.00 / kg	1kg	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

Fmoc-Trp(Boc)-OH
143824-78-6
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Fmoc-Trp(Boc)-OH
143824-78-6
US $5.00 / kg
≥99%
Jinan Finer Chemical Co., Ltd

Fmoc-Trp(Boc)-OH
143824-78-6
US $3.00-1.00 / kg
99%
Henan Fengda Chemical Co., Ltd

Fmoc-Trp(Boc)-OH Spectrum

Fmoc-Trp(Boc)-OH(143824-78-6)¹HNMR

143824-78-6(Fmoc-Trp(Boc)-OH)Related Search:

Fmoc-Lys(Boc)-OH L-Tryptophan BUTYL OLEATE 9-Fluorenylmethyl chloroformate tert-Butyl acetate

N-(tert-Butoxycarbonyl)-L-alanine L-5-Hydroxytryptophan Fmoc-Phe-OH Nalpha-Fmoc-Ndelta-trityl-L-glutamine L-Fmoc-Aspartic acid alpha-tert-butyl ester

METHOXYCARBONYLSULFENYL CHLORIDE Cyhalofop-butyl Butyl acetate N-(9-Fluorenylmethoxycarbonyloxy)succinimide Boc-Aib-OH

2-Butoxyethanol Buprofezin tert-Butanol

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FMOC-TRP(BOC)-OH FMOC-TRYPTOPHAN(BOC)-OH FMOC-NIN-T-BUTYLOXYCARBONYL-L-TRYPTOPHAN FMOC-N-IN-BOC-L-TRYPTOPHAN FMOC-N-BOC-L-TRYPTOPHAN FMOC-L-TRYPTOPHAN(BOC) FMOC-L-TRYPTOPHAN (TBOC) FMOC-L-TRP(TBOC)-OH N-ALPHA-FMOC-N-IN-T-BOC-L-TRYPTOPHAN N-ALPHA-FMOC-N(IN)-BOC-L-TRYPTOPHAN N-ALPHA-FMOC-N-IN-TERT-BOC-L-TRYPTOPHAN N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-IN-T-BUTOXYCARBONYL-L-TRYPTOPHAN N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-NIN-T-BUTYLOXYCARBONYL-L-TRYPTOPHAN N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-IN-T-BUTYL-OXYCARBONYL-L-TRYPTOPHAN NALPHA-9-FLUORENYLMETHYLOXYCARBONYL-N(IN)-TERT-BUTOXYCARBONYL-L-TRYPTOPHAN N ALPHA-9-FLUORENYLMETHYLOXYCARBONYL-N(IN)-T-BUTOXYCARBONYL-L-TRYPTOPHAN Fmoc-Trp(Boc)-OH ,98% FMoc-Trp(Boc)-OH N-α-FMoc-N-in-Boc-L-tryptophan 1-Boc-N^a-FMoc-L-tryptophan, 97% Nα-[(9H-Fluoren-9-ylMethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan 1-Boc-N-FMoc-L-tryptophan, 97% N1-Boc-Nalpha-Fmoc-L-tryptophan Fmoc-Trp(Boc)-OH Fmoc-Trp(Boc)-OH >=97.0% (HPLC) (2S)-3-{1-[(tert-Butoxy)carbonyl]-1H-indol-3-yl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid Nα-Fmoc-Nin-Boc-L-tryptophan≥ 98% (HPLC) N_α-Fmoc-N_(in)-Boc-L-tryptophan N-tert-Butoxycarbonyl-N-9-fluorenylmethoxycarbonyl-L-tryptophan N-α-Fmoc-N-in-Boc-L-tryptophan FMOC-TRP(BOC)-OH 99+% N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-N-IN-T-BUTYLOXYCARBONYL-L-TRYPTOPHAN FMOC-L-TRYPTOPHANE N (in) -Boc- N α -Fmoc- L -tryptophan Nin-tert-Butoxycarbonyl-NALPHA-9-fluorenylmethoxycarbonyl-L-tryptophan FMOC-N-BOC-L-TRYPTOPHAN (FMOC-L-TRP(BOC)-OH) 1-[(TERT-BUTYL)CARBONYL]-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-TRYPTOPHAN Nα-Fmoc-N(in)-Boc-L-tryptophan, N(in)-Boc-Nα-Fmoc-L-tryptophan N1-Boc-Nalpha-Fmoc-L-tryptophan Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-IN-TERT-BUTYLOXYCARBONYL-L-TRYPTOPHAN N(IN)-BOC-N-ALPHA-FMOC-L-TRYPTOPHAN Fmoc-Trp(Boc)-OH (contains 8% solvents) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid (2R)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid Fmoc-Trp(Boc)-OH, 97.0% (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoicacid Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan> FMOC-TRP(BOC)-OH 25 G FMOC-TRP(BOC)-OH 100 G N1-Boc-NaL pha-Fmoc-L L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- N(α)-fmoc-N(in)-boc-L-tryptophan (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoicaci Fmoc-Trp(Boc)-OH USP/EP/BP Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan (9H-Fluoren-9-yl)MethOxy]Carbonyl Trp(Boc)-OH N-Fmoc-NIn-Boc-L-trp FMOC-TRP(BOC)