N-Acetyl-L-methionine
- CAS No.
- 65-82-7
- Chemical Name:
- N-Acetyl-L-methionine
- Synonyms
- NAM;N-Acetylmethionine;AC-MET-OH;ACETYL-L-METHIONINE;N-ACETYL-L-METHIONINE:AC-MET-OH;methionin;n-acetyl-l-methionin;N-AC-L-MET;Ac-L-Met-OH;AC-METHIONINE
- CBNumber:
- CB3394487
- Molecular Formula:
- C7H13NO3S
- Molecular Weight:
- 191.25
- MDL Number:
- MFCD00064441
- MOL File:
- 65-82-7.mol
- MSDS File:
- SDS
| Melting point | 103-106 °C(lit.) |
|---|---|
| alpha | -20 º (c=4 H2O) |
| Boiling point | 235 °C(Press: 12 Torr) |
| Density | 1.2684 (rough estimate) |
| refractive index | -21 ° (C=1, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: soluble100mg/mL, clear, colorless |
| pka | 3.50±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]20/D -21.0±1.0°, c = 1% in H2O |
| Merck | 14,96 |
| BRN | 1725552 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | XUYPXLNMDZIRQH-LURJTMIESA-N |
| LogP | -0.885 (est) |
| CAS DataBase Reference | 65-82-7(CAS DataBase Reference) |
| FDA 21 CFR | 172.372 |
| Substances Added to Food (formerly EAFUS) | N-ACETYL-L-METHIONINE |
| FDA UNII | 9J12WX5B6A |
| NIST Chemistry Reference | N-acetylmethionine(65-82-7) |
| EPA Substance Registry System | L-Methionine, N-acetyl- (65-82-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H335 | |||||||||
| Precautionary statements | P280-P302+P352-P362+P364 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | PD0480000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29309070 | |||||||||
| NFPA 704 |
|
N-Acetyl-L-methionine price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 01310 | N-Acetyl-L-methionine ≥98.5% (T) | 65-82-7 | 5g | $54.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 01310 | N-Acetyl-L-methionine ≥98.5% (T) | 65-82-7 | 25g | $207 | 2024-03-01 | Buy |
| TCI Chemical | A2056 | N-Acetyl-L-methionine >98.0%(HPLC)(T) | 65-82-7 | 5g | $20 | 2024-03-01 | Buy |
| TCI Chemical | A2056 | N-Acetyl-L-methionine >98.0%(HPLC)(T) | 65-82-7 | 25g | $34 | 2024-03-01 | Buy |
| Alfa Aesar | B24312 | N-Acetyl-L-methionine, 99% | 65-82-7 | 5g | $41.65 | 2024-03-01 | Buy |
N-Acetyl-L-methionine Chemical Properties,Uses,Production
Identification Test
Take a sample of 250mg, get it dissolved it in 2.5ml isopropyl alcohol and get it diluted with water to 25ml. Take this liquid of 10ml and get it diluted with water to 100m1. Then take the liquid of 0.5,30 and 50μ1 after two dilutions. Drop it at the place with a distance of 2cm from the bottom edge of the thin-layer chromatographic plate. The plate is coated with silica gel (Namely, 20cm * 20cm Brinkman silica gel of 60.250nm, or the equivalent). In a sealed and balanced thin-layered chromatography expansion tank, The chromatography was splayed out by 10cm, and the developer was composed of n-butanol and the mixture of acetic acid and water in the proportion 75：20=20.
Dry the plate overnight. Then spray the chromatography plate with a new iodoplatinate solution mixed with 10 percent chloroplatinic acid of 3ml, water of 97ml and 6 percent potassium iodide solution of 100ml. The sample shall be formed - a separate color spot with a Rf value of 0.67~0.1
Content Analysis
Weigh accurately about 250mg sample and put it in a flask with glass stopper. Add 100ml water, 5g dipotassium hydrogen phosphate, 2g potassium dihydrogen phosphate and 2g potassium iodide. Get it fully mixed and dissolved, plus 0. 1mol/L iodine solution of 50.0m1. Then stopper it and blend it. Leave it stand for 30 minutes and titrate excess iodine with 0.1mol / L sodium thiosulfate. Meanwhile conduct blank titration experiment. Iodine solution per Ml 0.1mol/L equals to this product (C7H13NO3S) 9.563mg.
Toxicity Grade
Safe for food(FDA，§172．372，2000).
Acute Toxicity
Vein - mouse LD50: 435 mg / kg
Use Quantity
Account for 3.1% of the total protein content in food (Calculated by free L- methionine).
It shall not be used for infant food and food containing adding nitrite / nitrate (FDA, 172.3722000).
Chemical Properties
white crystals
Uses
N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold-?stored platelets.
Definition
ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.
Safety Profile
Poison by intravenous route. When heated to decomposition emits toxic fumes of NOX,.
Purification Methods
Crystallise N-acetyl-L-methionine from Me2CO, H2O or EtOAc. Dry it in a vacuum over P2O5. Its solubility at 25o in H2O is 30.7%, and in Me2CO it is 29.5%. [Mitzi & Schueter Biochim Biophys Acta 27 168 1958, Birnbaum et al. J Biol Chem 194 455 1952, Beilstein 4 IV 3206.]
N-Acetyl-L-methionine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from N-Acetyl-L-methionine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-15 | N-Acetyl-L-Methionine
65-82-7
|
US $1.00 / g | 10g | 99 | 20ton | ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | |
 |
2024-03-29 | N-Acetyl-L-methionine
65-82-7
|
US $0.00-0.00 / g | 1g | 99.99% | 20 tons | airuikechemical co., ltd. | |
 |
2024-03-08 | N-acetyl-L-methionine
65-82-7
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd |
-
- N-Acetyl-L-Methionine
65-82-7
- US $1.00 / g
- 99
- ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
-
- N-Acetyl-L-methionine
65-82-7
- US $0.00-0.00 / g
- 99.99%
- airuikechemical co., ltd.
-
- N-acetyl-L-methionine
65-82-7
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd
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