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4-Dodecanolide

CAS No.
2305-05-7
Chemical Name:
4-Dodecanolide
Synonyms
GAMMA-DODECALACTONE;γ-Dodecalactone;dodecalactone;γ-dodecalactone,4-dodecanolide,dihydro-5-octyl-2(3H)-furanone;FEMA 2400;γ-Dodecanolide;4-DODECANOLIDE;G-DODECALACTONE;Dodecanolide-1,4;g-Dodecanolactone
CBNumber:
CB3427330
Molecular Formula:
C12H22O2
Molecular Weight:
198.3
MDL Number:
MFCD00036499
MOL File:
2305-05-7.mol
Last updated:2024-04-26 17:21:34

4-Dodecanolide Properties

Melting point 17-18 °C(lit.)
Boiling point 130-132 °C1.5 mm Hg(lit.)
Density 0.936 g/mL at 25 °C(lit.)
vapor pressure 7.3hPa at 20℃
refractive index n20/D 1.452(lit.)
FEMA 2400 | GAMMA-DODECALACTONE
Flash point >230 °F
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Sparingly), Methanol (Slightly)
form Oil
color Colourless
Specific Gravity 0.94
Odor at 100.00 %. fatty peach sweet metallic fruity
Odor Type fruity
Water Solubility 60mg/L at 20℃
JECFA Number 235
BRN 126680
InChIKey WGPCZPLRVAWXPW-UHFFFAOYSA-N
LogP 2.7 at 20℃
CAS DataBase Reference 2305-05-7(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) GAMMA-DODECALACTONE
EWG's Food Scores 1
FDA UNII YX9N4581LU
NIST Chemistry Reference «GAMMA» dodecalactone(2305-05-7)
EPA Substance Registry System 2(3H)-Furanone, dihydro-5-octyl- (2305-05-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  LU3600000
Hazard Note  Irritant
HS Code  29322090
Toxicity skn-rbt 500 mg/24H MOD FCTXAV 14,751,76
NFPA 704
1
2 0

4-Dodecanolide price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W240015 γ-Dodecalactone natural, ≥98%, FG 2305-05-7 100g $210 2024-03-01 Buy
Sigma-Aldrich W240015 γ-Dodecalactone natural, ≥98%, FG 2305-05-7 1kg $1120 2024-03-01 Buy
Sigma-Aldrich W240001 γ-Dodecalactone ≥97%, FCC, FG 2305-05-7 sample-k $54.6 2024-03-01 Buy
Sigma-Aldrich W240001 γ-Dodecalactone ≥97%, FCC, FG 2305-05-7 100g $79.8 2024-03-01 Buy
Sigma-Aldrich W240001 γ-Dodecalactone ≥97%, FCC, FG 2305-05-7 1kg $148 2024-03-01 Buy
Product number Packaging Price Buy
W240015 100g $210 Buy
W240015 1kg $1120 Buy
W240001 sample-k $54.6 Buy
W240001 100g $79.8 Buy
W240001 1kg $148 Buy

4-Dodecanolide Chemical Properties,Uses,Production

Chemical Properties

γ-Dodecalactone has a fatty, peachy, somewhat musky odor and buttery, peach-like flavor

Occurrence

Reported found in apricot, cooked pork, milk products, peach, bilberry, guava fruit, papaya, pineapple, fresh blackberry, strawberry, celery leaves and stalks, celery root, blue cheeses, cheddar cheese, Swiss cheese, meats, beer, rum, mushrooms, plum brandy, quince, chervil, naranjilla fruit and other natural sources

Uses

4-Dodecanolide was one of the organic compounds from meat charbroiling operations studied.

Preparation

From 1-dodecen-12-oic acid with H2SO4 at 90°C; from 4-hydroxydodecanoic acid by lactonization; also from methylacrylate and octanol

Definition

ChEBI: Xi-Dihydro-5-octyl-2(3H)-furanone is a gamma-lactone.

Aroma threshold values

Detection: 7 ppb; aroma characteristics at 1.0%; sweet, creamy, fruity peach and apricot, lactonic, with dairy waxy and fatty nuances.

Taste threshold values

Taste characteristics at 1 to 10 ppm: sweet, fruity peach, milky fatty and waxy with a pulpy fruity mouthfeel.

Synthesis Reference(s)

Journal of the American Chemical Society, 108, p. 3745, 1986 DOI: 10.1021/ja00273a032
Organic Syntheses, Coll. Vol. 7, p. 400, 1990

Safety Profile

A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors

4-Dodecanolide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 242)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807 admin@hbouhuang.com China 2991 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 2263 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58

View Lastest Price from 4-Dodecanolide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
γ Dodecalactone pictures 2024-04-27 γ Dodecalactone
2305-05-7
US $5.00 / kg 1kg 99.92% 50000tons Ouhuang Engineering Materials (Hubei) Co., Ltd
4-Dodecanolide pictures 2023-08-15 4-Dodecanolide
2305-05-7
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
4-Dodecanolide pictures 2023-06-08 4-Dodecanolide
2305-05-7
US $10.00 / KG 1KG 99.% 10 ton Hebei Guanlang Biotechnology Co,.LTD
  • γ Dodecalactone pictures
  • γ Dodecalactone
    2305-05-7
  • US $5.00 / kg
  • 99.92%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • 4-Dodecanolide pictures
  • 4-Dodecanolide
    2305-05-7
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • 4-Dodecanolide pictures
  • 4-Dodecanolide
    2305-05-7
  • US $10.00 / KG
  • 99.%
  • Hebei Guanlang Biotechnology Co,.LTD
(±)-γ-octyl-γ-butyrolactone DIHYDRO-5-OCTYL-2-FURANONE (Z)-4-HYDROXY-6-DODECENOICACIDLACTONE Dihydro-5-octylfuran-2(3H)-on DODECALACTON-GAMMA Natural gamma dodecalactone 5-Octyldihydrofuran-2(3H)-one GAMMA-DODECALACTONE, NATURAL (±)-γ-Octyl-γ-butyrolactone, (±)-Dihydro-5-octyl-2(3H)-furanone (±)-γ-Octyl-γ-butyrolactone, (±)-4-Dodecanolide, (±)-Dihydro-5-octyl-2(3H)-furanone 4,5-Dihydro-5-octyl-2(3H)-furanone 4-Hydroxylauric acid lactone 5-Octyl-4,5-dihydrofuran-2(3H)-one γ-Dodecanolide γ-Dodecalactone >= 99.0%, Natural, FCC DODECALACTONE, gamma(RG) (±)-4-Dodecanolide,(±)-γ-Octyl-γ-butyrolactone, (±)-Dihydro-5-octyl-2(3H)-furanone γ-Dodecalactone,Natural gamma-Dodecalactone gamma-Laurolactone γ-Dodecalactone,(±)-γ-Octyl-γ-butyrolactone, (±)-4-Dodecanolide, (±)-Dihydro-5-octyl-2(3H)-furanone dihydro-5-octylfuran-2(3H)-one (+/-)-4-DODECANOLIDE, STANDARD FOR GC GAMMA-DODECALACTONE 97+% FCC g-Dodecanolactone 5-Octyldihydro-2(3H)-furanone dihydro-5-octyl-2(3h)-furanon Dodecanoic acid, 4-hydroxy-, gamma-lactone Dodecanolide-1,4 gamma-n-Octyl-gamma-n-butyrolactone gamma-DodecalacetoneFCC Dihydro-5-octyl-1[3H]-furanone DODECANYL-LACTONE DODECALACTONE, GAMMA- (+/-)-DIHYDRO-5-OCTYL-2(3H)-FURANONE FEMA 2400 GAMMA-LAUROLACTONE (+/-)-GAMMA-OCTYL-GAMMA-BUTYROLACTONE GAMMA-DODECANOLACTONE G-DODECALACTONE 5-OCTYL-BUTYROLACTONE (+/-)-4-DODECANOLIDE 4-DODECANOLIDE 2-(3H)-Furanone, 5-octyldihydro- 2(3H)-Furanone, dihydro-5-octyl- 4-Hydroxydodecanoic acid lactone 4-Hydroxydodecanoic acid, gamma-lactone 5-octyloxolan-2-one 5-octyl-2-oxolanone gamma-DODECALACTONE FCC γ-Dodecanolactone> 4-Dodecanolide USP/EP/BP γ-Dodecanolactone γ-dodecalactone,4-dodecanolide,dihydro-5-octyl-2(3H)-furanone dodecalactone GAMMA-DODECALACTONE γ-Dodecalactone 2305-05-7 2305-05-07