ChemicalBook >> CAS DataBase List >>10-Deacetylbaccatin III
10-Deacetylbaccatin III
- CAS No.
- 32981-86-5
- Chemical Name:
- 10-Deacetylbaccatin III
- Synonyms
- 10-DAB;10-DEACETYLBACCATIN;10-DAB Ⅲ;10-Deacetyl Baccatin lll;ó;NH24841;10DBA III;10-DAB-III;10-Deacetyl;10-Dab98.5%
- CBNumber:
- CB3447497
- Molecular Formula:
- C29H36O10
- Molecular Weight:
- 544.59
- MDL Number:
- MFCD00132913
- MOL File:
- 32981-86-5.mol
- MSDS File:
- SDS
Last updated:2024-04-02 17:31:45
| Melting point | 231-236 °C |
|---|---|
| Boiling point | 717℃ |
| alpha | -44.5 º (c=1, methanol 25 ºC) |
| Density | 1.2007 (rough estimate) |
| refractive index | 1.5376 (estimate) |
| Flash point | >110°(230°F) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH) |
| form | Powder |
| pka | 11.50±0.70(Predicted) |
| color | white |
| Water Solubility | INSOLUBLE |
| InChIKey | YWLXLRUDGLRYDR-IYNRKYTHSA-N |
| SMILES | O1C[C@@]2(OC(C)=O)[C@@]3([H])[C@H](OC(=O)C4=CC=CC=C4)[C@@]4(O)C(C)(C)C(=C(C)[C@@H](O)C4)[C@@H](O)C(=O)[C@]3(C)[C@@H](O)C[C@@]12[H] |
| LogP | 0.156 (est) |
| CAS DataBase Reference | 32981-86-5(CAS DataBase Reference) |
| FDA UNII | 4K6EWW2Z45 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335-H340-H350-H373 | |||||||||
| Precautionary statements | P201-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25 | |||||||||
| Safety Statements | 45-38-36/37/39-28A-24/25 | |||||||||
| RIDADR | 1544 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
10-Deacetylbaccatin III price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D3676 | 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) | 32981-86-5 | 5mg | $371 | 2024-03-01 | Buy |
| Sigma-Aldrich | D3676 | 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) | 32981-86-5 | 1mg | $108 | 2023-06-20 | Buy |
| TCI Chemical | D4148 | 10-Deacetylbaccatin III >98.0%(HPLC) | 32981-86-5 | 100mg | $111 | 2024-03-01 | Buy |
| TCI Chemical | D4148 | 10-Deacetylbaccatin III >98.0%(HPLC) | 32981-86-5 | 500mg | $352 | 2024-03-01 | Buy |
| Alfa Aesar | J66228 | 10-Deacetylbaccatin III, 95% | 32981-86-5 | 25mg | $734 | 2021-12-16 | Buy |
10-Deacetylbaccatin III Chemical Properties,Uses,Production
Chemical Properties
10-Deacetylbaccatin III is White Solid
Uses
10-Deacetylbaccatin III is a intermediate in the synthesis of Taxol and derivatives
Uses
10-Deacetyl Baccatin III is an impurity of Paclitaxel (P132500) and derivatives.
Uses
10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties. 10-DAB (10-Deacetylbaccatin) can be gained from the le
Definition
ChEBI: 10-deacetylbaccatin III is a tetracyclic diterpenoid and a secondary alpha-hydroxy ketone. It is functionally related to a baccatin III.
General Description
10-Deacetylbaccatin III, also known as Paclitaxel Impurity 19, is an impurity of Paclitaxel. Paclitaxel is a chemotherapy drug. Chemotherapy is a treatment that destroys cancer cells using anti-cancer drugs. Paclitaxel is the non-branded name of the drug, but you may hear it called by one of its brand names such as Taxol. Some people are given a drug called nab-paclitaxel (Abraxane).
Biological Activity
10-dab (also known as 10-deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the pacific yew tree taxus brevifolia as well as other species of the genus taxus. due to the low availability of taxol from its natural sources, 10-dab is used as a raw material for the preparation of taxol and its derivatives. being easily extracted from the annual cute of the yew leaves, 10-dab has a very folded chemical structure with the α hydroxyl group hindered at c-13 easily to form a hydrogen bond with the 4α acetyl group.f. gueritte-voegelein, v. senilh, b. david, d. guenard and p. potier. chemical studies of 10-deacetyl baccatin iii hemisynthesis of taxol derivatives. tetrahedron 1986; 42(16): 4451-4460
10-Deacetylbaccatin III Preparation Products And Raw materials
Global( 605)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 | zhang@hbbocao.com | China | 1035 | 58 |
| Guangzhou Tosun Pharmaceutical Limited | +8618922120635 | sales@toref-standards.com | China | 1000 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 | kyra@quanjinci.com | China | 1532 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7613 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Jiangsu Yew Pharmaceutical Co., Ltd. | +86-510-66865338 +86-189-2133-5032 @ | junwenjiang@live.cn | CHINA | 30 | 60 |
View Lastest Price from 10-Deacetylbaccatin III manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-11 | Paclitaxel Impurity 19
32981-86-5
|
US $0.00-0.00 / mg | 10mg | 99.46% | 10g/month | Guangzhou Tosun Pharmaceutical Limited | |
 |
2024-04-02 | 10-Deacetylbaccatin III
32981-86-5
|
US $35.00-1.40 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-11-29 | 10-Deacetylbaccatin III
32981-86-5
|
US $15.00 / kg | 1kg | 0.99 | 1000000tons | Wuhan Quanjinci New Material Co.,Ltd. |
-
- Paclitaxel Impurity 19
32981-86-5
- US $0.00-0.00 / mg
- 99.46%
- Guangzhou Tosun Pharmaceutical Limited
-
- 10-Deacetylbaccatin III
32981-86-5
- US $35.00-1.40 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 10-Deacetylbaccatin III
32981-86-5
- US $15.00 / kg
- 0.99
- Wuhan Quanjinci New Material Co.,Ltd.
32981-86-5(10-Deacetylbaccatin III)Related Search:
Acetylferrocene
Acetylacetone
N-ACETYL-L-TYROSINE ETHYL ESTER
Baccatine III
(2R,3S)-N-Benzoyl-3-phenyl Isoserine
Docetaxel Metabolite M4
10-Oxo Docetaxel
13-O-(Triethylsilyl) Baccatin III
2-Debenzoyl-2-pentenoyl Docetaxel
Docetaxel Impurity 5
Docetaxel impurity 1/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-6,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(((2,2,2-trichloroethoxy)carbonyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl
Docetaxel Impurity 36
Docetaxel
(2S,3S)-methyl 3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropanoate
HLCSYHHJEMPKSY-RRKHLBDSSA-N
1of4
10-deacetylbaccatin11
10-deacetylbaccatiniii(extaxusbaccata)
10-DEACETYLBACCATIN III FROMTAXUS BACCAT A
10-Dab98.5%
10-Deacetylbaccatine(III)
10-Deacetyl Baccatin ¢
10-Deacetylbaccatine
10-DAB III(10-DEACETYL BACCATIN III) 99%
DEACETYLBACCATIN-III, 10(P)
10-DAB(10-deacetylbaccatin)
10-Deacetyl
DESACETYLBACCATINE
BACCATIN III, 10-DEACETYL-
10-Deacetylbaccatin III
10-O-DEACETYLBACCATIN III
Docetaxel IMpurity E (10-Deacetyl Baccatin III)
ó
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-
Docetaxel impurity E
10-Deacetylbaccatin III, >=99%
10-deacetyl Chiba Cardin Ⅲ
12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3
(2AR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-
10-DEACETYLBACCATIN III (EX TAXUS BACCATA), CONTAINS CA 0.5 MOLE OF METHANOL 95%
10-DEACETYL BACCATIN (10-DAB )
10-Desacetylbaccatin III
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one,12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-,[2aR-(2aα,4β,4aβ,6β,9α,11α,12α,12aα,12bα)]-
12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
10-DAB-III
10-DEACETYLBACCATIN III, 95%, FROM TAXUS BACCATA
10-Deacetyl Baccatin ￠ó
12b-(Acetyloxy)-12-(Benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-Dodecahydro-4,6,9,11-Tetrahydroxy-4a,8,13,13-Tetramethyl-7,11-Methano-5h-Cyclodeca[3,4]
10-Deacetylbaccatin III ,97%
10-Decaacetyl baccatin III
10DBA III
10-Deacetyl baccatine IIII
10-Deacetylbaccatin Ⅲ(10-DAB)
5β,20-Epoxy-4-(acetyloxy)-1,7β,10β,13α-tetrahydroxy-9-oxotax-11-en-2α-yl benzoate
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetraMethyl-7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
Deacetylbaccatin III
high quality 10-deacetylbacctin Ⅲ(10-DAB) CAS 32981-86-5 CAS NO.32981-86-5
2-bromo-4-chloropropiophenone CAS NO.877-37-2
10-Deacetylbaccatin III 32981-86-5
Paclitaxel Impurity 19
Docetaxel EP impurity E，10-desacetyl-baccatin III
10-Deacetylbacatin III
Docetaxel EP Impurity E
Docetaxel Impurity 5(Docetaxel EP Impurity E)
NH24841
10-DAB：10-Deacetylbaccatin III
Docetaxel EP Impurity E
(10-Deacetyl Baccatin III)
10-DeacetylbaccatinIII>
Docetaxel impurity E CRS
3-(5-chloro-2-fluorobenzyl)isonicotinic acid
10-Deacetylbaccatin III USP/EP/BP
1-Deacetylbaccatin III
10-Deacetylbaccatin IIIQ: What is
10-Deacetylbaccatin III Q: What is the CAS Number of
10-Deacetylbaccatin III Q: What is the storage condition of
10-Deacetylbaccatin III Q: What are the applications of
10-Deacetylbaccatin III
10-Deacetylbaccatin III, 95%,