(+)-PULEGONE
- CAS No.
- 89-82-7
- Chemical Name:
- (+)-PULEGONE
- Synonyms
- PULEGONE;(R)-PULEGONE;PULEGON;P-MENTH-4(8)-EN-3-ONE;2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE;FEMA 2963;NSC 15334;D-PULEGONE;d-Puregone;(+)-PULEONE
- CBNumber:
- CB3448348
- Molecular Formula:
- C10H16O
- Molecular Weight:
- 152.23
- MDL Number:
- MFCD00063000
- MOL File:
- 89-82-7.mol
- MSDS File:
- SDS
Melting point | <=25°C |
---|---|
alpha | D20 +21°; 20546 +28.2° |
Boiling point | 224 °C(lit.) |
Density | 0.937 g/mL at 25 °C(lit.) |
vapor pressure | 138 mm Hg ( 25 °C) |
FEMA | 2963 | PULEGONE |
refractive index |
n |
Flash point | 185 °F |
storage temp. | 2-8°C |
solubility | Chloroform (Sparingly), Methanol (Slightly) |
form | Liquid |
Specific Gravity | 0.94 |
color | Clear colorless to yellow |
Odor | at 100.00 %. peppermint camphor fresh herbal buchu |
Odor Type | minty |
optical activity | [α]20/D +23.5°, neat |
λmax | 255nm(lit.) |
Merck | 14,7937 |
JECFA Number | 753 |
BRN | 2040703 |
Dielectric constant | 9.5(20℃) |
InChIKey | NZGWDASTMWDZIW-MRVPVSSYSA-N |
LogP | 2.56 |
Substances Added to Food (formerly EAFUS) | PULEGONE |
CAS DataBase Reference | 89-82-7(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 4LF2673R3G |
Proposition 65 List | Pulegone |
IARC | 2B (Vol. 108) 2016 |
EPA Substance Registry System | d-Pulegone (89-82-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H351 | |||||||||
Precautionary statements | P202-P264-P270-P280-P301+P312-P308+P313 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22 | |||||||||
Safety Statements | 23-24/25 | |||||||||
RIDADR | 2810 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | OT0261000 | |||||||||
F | 10-23 | |||||||||
HS Code | 2914 29 00 | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
Toxicity | LD50 orally in Rabbit: 470 mg/kg LD50 dermal Rabbit 3090 mg/kg | |||||||||
NFPA 704 |
|
(+)-PULEGONE price More Price(51)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | W296309 | (R)-(+)-Pulegone ≥90% | 89-82-7 | 100g | $132 | 2024-03-01 | Buy |
Sigma-Aldrich | W296309 | (R)-(+)-Pulegone ≥90% | 89-82-7 | 1kg | $968 | 2024-03-01 | Buy |
Sigma-Aldrich | CRM40371 | (+)-Pulegone solution certified reference material, 2000?μg/mL in methanol, ampule of 1?mL | 89-82-7 | 1mL | $82.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.18665 | (R)-(+)-Pulegone for synthesis | 89-82-7 | 10ml | $135 | 2024-03-01 | Buy |
Sigma-Aldrich | 04620590 | (+)-Pulegone primary pharmaceutical reference standard | 89-82-7 | 100mg | $384 | 2024-03-01 | Buy |
(+)-PULEGONE Chemical Properties,Uses,Production
Chemical Properties
clear colorless to yellow liquid
Chemical Properties
Pulegone.has.a.pleasant.odor,somewhat.similar.to.peppermint.and.camphor.
Occurrence
The l-form is found in the essential oils of Agastache formosana, Israeli orange, Barosma betulina and Barosma crenulata; the d-form is the most abundant and is found in pennyroyal oils. Also reported found in rabbiteye blueberry, black currants (buds), fresh blackberry, heated blackberry, peppermint oil, corn mint oil, spearmint oil, Scotch spearmint oil, other Mentha oils, thyme, black tea, origanum, Ocimum basilicum varieties, rosemary, lemon balm, buchu oil, anise hyssop, sweet grass oil and German chamomile oil.
Uses
A monoterpene, commonly found in the essential oils of Nepeta cataria (Catnip).
Definition
ChEBI: The (5R)-enantiomer of p-menth-4(8)-en-3-one.
Aroma threshold values
Detection:.130.ppb..Aroma.characteristics.at.1.0%:.minty.cooling,.herbal.green,.sweet,.clean.spicy,.with. wintergreen.nuances.
Taste threshold values
Taste characteristics at 20 ppm: minty, terpy, cooling, woody pine, citrus lime, with fresh green peppermint notes.
General Description
(R)-(+)-Pulegone, a monoterpene ketone found in the essential oil of pennyroyal, can induce abortion.
Biochem/physiol Actions
Taste at 20 ppm
Synthesis
Isolated.from.pennyroyal.oil.(Moroccan.or.Spanish);.synthesis.from.3-methyl.cyclohexanone..The.structure.has.been.defined. by.the.work.of.several.authors;.the.d-,.l-.and.dl-forms.are.known;.the.dl-form.is.prepared.synthetically.and.is.not.found.in.nature.
target
GABA Receptor
Purification Methods
Purify pulegone via the semicarbazone which has m 174o (from MeOH) and [] D +68.2o (c 1, CHCl3). Fractionally distil it in vacuo. [Short & Read J Chem Soc 1309 1939]. [Erskine & Waight J Chem Soc 3425 1960, cf Ort Org Synth 65 203 1987, Beilstein 7 III 334, 7 IV 188.]
(+)-PULEGONE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19536 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from (+)-PULEGONE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-15 | (+)-PULEGONE
89-82-7
|
US $20.00-1.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | ||
2023-10-09 | (+)-PULEGONE
89-82-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2023-09-06 | (+)-PULEGONE
89-82-7
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
- (+)-PULEGONE
89-82-7
- US $20.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
- (+)-PULEGONE
89-82-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- (+)-PULEGONE
89-82-7
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.