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DIBENZO(A,I)PYRENE

CAS No.
191-30-0
Chemical Name:
DIBENZO(A,I)PYRENE
Synonyms
DBC;DBC-d7;db(a,1)p;Db(a,l)p;NSC 90324;ba51-090462;Ba 51-090462;NSC 90324-d7;Ba 51-090462-d7;DIBENZ(A,I)PYRENE
CBNumber:
CB3451069
Molecular Formula:
C24H14
Molecular Weight:
302.37
MDL Number:
MFCD00055882
MOL File:
191-30-0.mol
MSDS File:
SDS
Last updated:2023-05-06 17:15:43

DIBENZO(A,I)PYRENE Properties

Melting point 228.05°C
Boiling point 378.4°C (rough estimate)
Density 1.1762 (estimate)
refractive index 1.9130 (estimate)
storage temp. 2-8°C
solubility Chloroform (Very Slightly, Heated), Dichloromethane (Slightly, Heated)
color Yellow to Orange
BRN 2054068
Stability Stable, but may be heat sensitive - keep cool. Combustible. Incompatible with strong oxidizing agents.
EWG's Food Scores 3
FDA UNII G3X629VE4A
IARC 2A (Vol. Sup 7, 92) 2010
Proposition 65 List Dibenzo[a,i]pyrene
Proposition 65 List Dibenzo[a,l]pyrene
EPA Substance Registry System Dibenzo[a,l]pyrene (191-30-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS08
Signal word  Danger
Hazard statements  H318-H341-H350
Precautionary statements  P202-P280-P305+P351+P338-P308+P313-P405-P501
Hazard Codes  Xn,T
Risk Statements  40-67-36/37/38-45-41-52/53
Safety Statements  23-24/25-36/37-45-26-53-39-61
RIDADR  2811
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III

DIBENZO(A,I)PYRENE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ERD-051 Dibenzo[a,l]pyrene vial of 25?mg, Cerilliant? 191-30-0 25mg $185 2024-03-01 Buy
Sigma-Aldrich BCR096 Dibenzo[a,l]pyrene BCR 191-30-0 100mg $1170 2024-03-01 Buy
TRC D416945 Dibenzo[def,p]chrysene 191-30-0 1mg $100 2021-12-16 Buy
Biosynth Carbosynth FD21528 Dibenzo[def,p]chrysene 191-30-0 1mg $170 2021-12-16 Buy
Medical Isotopes, Inc. 56687 Dibenzo[def,p]chrysene 191-30-0 100mg $2000 2021-12-16 Buy
Product number Packaging Price Buy
ERD-051 25mg $185 Buy
BCR096 100mg $1170 Buy
D416945 1mg $100 Buy
FD21528 1mg $170 Buy
56687 100mg $2000 Buy

DIBENZO(A,I)PYRENE Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

An active metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. DBC is the most potent tumorigen that has been identified to date. Dib enzo[def,p]chrysene (DBC) is a carcinogen and should be handled with appropriate caution.

Definition

ChEBI: Dibenzo[a,l]pyrene is an ortho- and peri-fused polycyclic arene. It has a role as a mutagen and a human metabolite.

General Description

Yellow odorless crystals or flakes. Water insoluble.

Air & Water Reactions

Dust/air mixtures may ignite and explode. Insoluble in water.

Reactivity Profile

Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as DIBENZO(A,I)PYRENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.

Safety Profile

Confirmed carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

Carcinogenicity

Dibenzo[a,1]pyrene is a class 2B carcinogen according to the IARC, although recent data suggest that it is a 2A carcinogen. In mouse studies, it has been more potent than benzo[a]pyrene in skin, and in rat studies, it has been more potent than 7,12-dimethylbenz [a]anthracene in the mammary gland. Dibenzo[a,l]pyrene was tested for carcinogenicity in studies of single and repeated dermal application to mice, as well as several initiation–promotion studies on mouse skin; all studies gave positive results. Dibenzo[a,l] pyrene also induced oral cavity tumors when applied dermally to the tongue of hamsters and lung tumors in mice following intraperitoneal injection. In addition to lung tumors, dibenzo[a,l]pyrene induced hepatic tumors and a variety of tumors at other sites when administered intraperitoneally to newborn mice. Multiple tumor sites were also observed following intragastric application of dibenzo[a,l]pyrene in mice. Intramamillary administration to rats also yielded positive results. Furthermore, two studies on fish demonstrated that nonmammalian species are also susceptible to dibenzo[a,l]pyreneinduced tumorigenicity.The most active metabolite is the potent 11,12-dihydrodiol of dibenzo[a,1] pyrene.

1013933-57-7
191-30-0
Synthesis of DIBENZO(A,I)PYRENE from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

DIBENZO(A,I)PYRENE Preparation Products And Raw materials

Raw materials

Preparation Products

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DIBENZO(A,L)PYRENE DIBENZO(A,I)PYRENE DIBENZ(A,L)PYRENE DIBENZ(A,I)PYRENE 3,4,9,10-DIBENZOPYRENE 1,2,9,10-Dibenzopyrene 1,2:3,4-Dibenzopyrene 1,2:9,10-Dibenzopyrene 2,3:4,5-Dibenzopyrene 4,5,6,7-Dibenzpyrene 4,5:6,7-Dibenzpyrene Ba 51-090462 ba51-090462 db(a,1)p Db(a,l)p Dibenzo(a,1)pyrene Dibenzo(a,d)pyrene 1,2,3,4-DIBENZPYRENE 1,2:7,8-DIBENZPYRENE dibenzo(d,e,f,p)chrysene dibenzo(def,p)chrysene Dibenzo[def,p]chrysene Dibenzo[a,l]pyrene (purity) 46726, Dibenzo[a,l]pyrene (purity) dibenz[a,l]pyrene solution 2,3:4,5-Dibenzpyrene DBC NSC 90324 1,2,9,10-Dibenzopyrene-d7 1,2:3,4-Dibenzopyrene-d7 2,3:4,5-Dibenzpyrene-d7 4,5,6,7-Dibenzpyrene-d7 Ba 51-090462-d7 DBC-d7 NSC 90324-d7 DIBENZO (A,L) PYRENE, 1X1ML, CH2CL2 2000 UG/ML Dibenzo[a,l]pyrene Solution in Acetonitrile, 100μg/mL DBC (DiBenzo[def, p]chrysene CAS191-30-0 dibenzo[a,l]pyrene Naphtho[1,2,3,4-pqr]tetraphene Dibenzo(a,l)pyrene Solution Dibenzo(a,l)pyreneSolution,10mg/L,1ml Dibenzo(a,l)pyreneSolution,100mg/L,1ml Dibenzo(a,l)pyreneSolution,1000mg/L,1ml Dibenzo(a,l)pyreneSolution,200mg/L,2x5ml Dibenzo[A,L]Pyrene 200 μg/mL In Toluene Dibenzo(a,l)pyreneSolution,50mg/L,1ml Dibenz(a,l)pyrene@50 μg/mL in Toluene 191-30-0 6672-22-2 Analytical Chromatography Product Catalog Alphabetic Analytical Standards DIA - DIC Alpha Sort D DAlphabetic DIA - DIC