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MS012
- CAS No.
- 2089617-83-2
- Chemical Name:
- MS012
- Synonyms
- MS012;MS012 >=98% (HPLC);2,4-Quinazolinediamine, N2-hexyl-6,7-dimethoxy-N4-(1-methyl-4-piperidinyl)-
- CBNumber:
- CB34668236
- Molecular Formula:
- C22H35N5O2
- Molecular Weight:
- 401.55
- MDL Number:
- MOL File:
- 2089617-83-2.mol
Last updated:2023-03-31 09:12:59
MS012 Chemical Properties,Uses,Production
Description
MS012 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. MS012 exhibited stronger binding affinity to GLP (Kd = 46 ± 15 nM) than G9a (Kd = 610 ± 68 nM). MS012 was 13-fold selective for GLP over G9a. G9a-like protein (GLP) and G9a are highly homologous protein lysine methyltransferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains. GLP and G9a form a heterodimer complex and catalyze mono- and dimethylation of histone H3 lysine 9 and nonhistone substrates.
MS012 Preparation Products And Raw materials
Raw materials
Preparation Products
MS012 Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12007 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Energy Chemical | 58 |
| TargetMol Chemicals Inc. | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 58 |
MS012
MS012 >=98% (HPLC)
2,4-Quinazolinediamine, N2-hexyl-6,7-dimethoxy-N4-(1-methyl-4-piperidinyl)-
2089617-83-2