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4-Fluorobenzyl bromide

4-Fluorobenzyl bromide structure

CAS No.: 459-46-1

Chemical Name:: 4-Fluorobenzyl bromide

Synonyms: 1-(BROMOMETHYL)-4-FLUOROBENZENE;Of fluoride broMide;4-Fluorobenzyl bromi;4-FLUOROBENZYL BROMIDE;P-FLUOROBENZYL BROMIDE;α-BroMo-p-fluorotoluene;α-Bromo-4-fluorotoluene;1-bromo-3-fluorotoluene;à-bromo-4-fluorotoluene;4-FLUOROBBENZYL BROMIDE

CBNumber:: CB3471414

Molecular Formula:: C7H6BrF

Molecular Weight:: 189.02

MDL Number:: MFCD00000359

MOL File:: 459-46-1.mol

MSDS File:: SDS

Last updated:2024-04-25 17:59:01

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4-Fluorobenzyl bromide Properties

Boiling point	85 °C15 mm Hg(lit.)
Density	1.517 g/mL at 25 °C(lit.)
refractive index	n20/D 1.547(lit.)
Flash point	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Chloroform
form	Liquid
Specific Gravity	1.517
color	Clear colorless to yellow
Sensitive	Lachrymatory
BRN	636507
InChIKey	NVNPLEPBDPJYRZ-UHFFFAOYSA-N
CAS DataBase Reference	459-46-1(CAS DataBase Reference)
FDA UNII	GKL3GW5GWH
NIST Chemistry Reference	«alpha»-Bromo-4-fluorotoluene(459-46-1)
EPA Substance Registry System	4-Fluorobenzyl bromide (459-46-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

Hazard Codes

Risk Statements

34-36

Safety Statements

26-36/37/39-45

RIDADR

UN 3265 8/PG 2

WGK Germany

Hazard Note

Corrosive/Lachrymatory

TSCA

Yes

HazardClass

PackingGroup

III

HS Code

29039990

NFPA 704

	0
3		0

4-Fluorobenzyl bromide price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	209538	4-Fluorobenzyl bromide 97%	459-46-1	5g	$41.4	2024-03-01	Buy
Sigma-Aldrich	209538	4-Fluorobenzyl bromide 97%	459-46-1	25g	$111	2024-03-01	Buy
TCI Chemical	F0214	4-Fluorobenzyl Bromide >97.0%(GC)	459-46-1	5g	$32	2024-03-01	Buy
TCI Chemical	F0214	4-Fluorobenzyl Bromide >97.0%(GC)	459-46-1	25g	$90	2024-03-01	Buy
Alfa Aesar	A10208	4-Fluorobenzyl bromide, 97%	459-46-1	10g	$45.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
209538	5g	$41.4	Buy
209538	25g	$111	Buy
F0214	5g	$32	Buy
F0214	25g	$90	Buy
A10208	10g	$45.65	Buy

4-Fluorobenzyl bromide Chemical Properties,Uses,Production

Chemical Properties

4-Fluorobenzyl bromide (C7H6BrF, CAS registry No. 459-46-1) is a colorless to light yellow liquid. Its flash point is 74.8 oC. It is stable at room temperature in closed containers under normal storage and handling conditions. 1,3-Difluorobenzene can react with water to form toxic fumes. Therefore, it should be stored in a tightly closed container and should be stored in a cool, dry and well-ventilated area away from incompatible substances.

Uses

4-Fluorobenzyl bromide is an important intermediate in organic chemistry. 4-Fluorobenzyl bromide can be used as alkylating reagent to participate in the alkylation reaction with sulfamic esters (R-O-SO2-NH2) in liquid-liquid phase transfer conditions, resulting in the preparation of the N-dialkyled products or the corresponding ethers by scission of the O-SO2 bond, depending on the nature of R.
4-Fluorobenzyl bromide can be used for the synthesis of glycyrrhetinic acid (GA) derivatives, which are slow-binding inhibitors of tyrosinase and have inhibitory effects on melanogenesis.

Chemical Properties

Colorless to light yellow liqui

Uses

4-Fluorobenzyl bromide was used in the preparation of:

3-acetyl-1-(4-fluorobenzyl)-4-hydroxy-1H-indole
1-(4-fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isatin
(S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)pyrrolidine-1-sulfonyl)isatin
8-bromo 9-(4-fluorobenzyl) adenine
8-bromo 3-(4-fluorobenzyl) adenine

Uses

4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials.

4-Fluorobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

4-Fluorobenzyl alcohol 2-IODOBENZAMIDE (4-FLUORO-BENZYL)-METHYL-AMINE 1-(4-FLUORO-BENZYL)-1H-PYRAZOL-3-YLAMINE N,N-Bis(2-chloroethyl)-p-fluorobenzylamine

1-[(4-fluorophenyl)methyl]imidazole 4-(4-Fluoro-benzyloxy)-benzonitrile 1-[(4-fluorophenyl)methyl]pyrrolidin-3-ol

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4-Fluorobenzyl bromide Suppliers

Global( 401)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2259	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	885	50
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	811	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Hangzhou FandaChem Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Shenzhen Nexconn Pharmatechs Ltd	58
Hebei Guanlang Biotechnology Co., Ltd.	58

View Lastest Price from 4-Fluorobenzyl bromide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-25	4-Fluorobenzyl Bromide 459-46-1	US $100.00-30.00 / kg	1kg	99.93%	1000kg per week	Ouhuang Engineering Materials (Hubei) Co., Ltd
2023-12-26	4-Fluorobenzyl bromide 459-46-1	US $100.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-07-28	4-Fluorobenzyl Bromide 459-46-1	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

4-Fluorobenzyl Bromide
459-46-1
US $100.00-30.00 / kg
99.93%
Ouhuang Engineering Materials (Hubei) Co., Ltd

4-Fluorobenzyl bromide
459-46-1
US $100.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

4-Fluorobenzyl Bromide
459-46-1
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

4-Fluorobenzyl bromide Spectrum

4-Fluorobenzyl bromide(459-46-1)MS 4-Fluorobenzyl bromide(459-46-1)¹HNMR 4-Fluorobenzyl bromide(459-46-1)IR1 4-Fluorobenzyl bromide(459-46-1)Raman

459-46-1(4-Fluorobenzyl bromide)Related Search:

Rocuronium bromide [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-pro p-1-enyl-cyclopropane-1-carboxylate Diethylstilbestrol Ethyl bromodifluoroacetate Fluorobenzene

Ethidium bromide 4-Fluorobenzyl chloride BRETYLIUM TOSYLATE Allyl bromide Sodium bromate

alpha-Chloro-o-fluorotoluene 4-n-Propoxyphenylacetylene Bromine 1,2-Bis(bromomethyl)benzene 9-BROMOFLUORENE

2-(Trifluoromethyl)benzyl bromide 1,2,4,5-TETRAKIS(BROMOMETHYL)BENZENE Methyl bromide

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α-Bromo-4-fluorotoluene 4-Fluorobenzyl bromi BroMobenzene of fluoride Of fluoride broMide 1-(Bromomethyl)-4-fluorobenzene, alpha-Bromo-4-fluorotoluene α-BroMo-p-fluorotoluene Toluene, α-broMo-p-fluoro- (6CI,7CI,8CI) The fluorine broMine benzyl ALPHA-BROMO-P-FLUOROTOLUENE ALPHA-BROMO-4-FLUOROTOLUENE 4-FLUOROBENZYL BROMIDE 1-(bromomethyl)-4-fluoro-benzen Benzene, 1-(bromomethyl)-4-fluoro- Toluene, alpha-bromo-p-fluoro- 4-fluoro(bromomethyl)benzene 1-bromo-3-fluorotoluene à-bromo-4-fluorotoluene 4-Fluorobenzyl bromide 90% 4-Fluorobenzyl Bromide p-Fluorobenzyl Bromide 4-FLUOROBENZYL BROMIDE 98% (GC) 4-Fluorobenzylbromide,97% α-Bromo-4-fluorotoluene, 1-Bromomethyl-4-fluorobenzene 4-Fluorobenzyl bromide ,98% 4-FLUOROBBENZYL BROMIDE A-BROMO-4-FLUOROTOLUENE P-FLUOROBENZYL BROMIDE 4-Fluoro-1-(bromomethyl)benzene 4-FluorobenzylBromide> 4-Fluorobenzyl bromide, 98%, for synthesis 4-Fluorobenzyl bromide ISO 9001：2015 REACH α-Bromo-p-fluorotoluene 1-(BROMOMETHYL)-4-FLUOROBENZENE 459-46-1 BENZYL HALIDE Building Blocks Aryl C7 Halogenated Hydrocarbons Organic Building Blocks Benzyl Fluoro-contained benzyl bromide series alkyl bromide|alkyl Fluorine Halogenated Heterocycles ,Pyrimidines Fluorinated benzene series bc0001