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BAY-6035

BAY-6035 structure

CAS No.: 2247890-13-5

Chemical Name:: BAY-6035

Synonyms: BAY-6035;inhibit,BAY-6035,Histone Methyltransferase,MEKK2,BAY6035,Inhibitor,BAY 6035,SMYD3,methylation;(2S)-1-(3-azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide;(2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide;1H-1,5-Benzodiazepine-7-carboxamide, 1-(3-azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-, (2S)-;(2S)-1-(3-Azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-7-carboxamide

CBNumber:: CB35867500

Molecular Formula:: C22H28N4O3

Molecular Weight:: 396.48

MDL Number:: MFCD31808259

MOL File:: 2247890-13-5.mol

Last updated:2023-09-04 15:51:00

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BAY-6035 Properties

storage temp.	Store at -20°C
solubility	DMSO:39.65(Max Conc. mg/mL);100.0(Max Conc. mM) Ethanol:39.65(Max Conc. mg/mL);100.0(Max Conc. mM)
form	A crystalline solid

BAY-6035 price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	25925	BAY-6035	2247890-13-5	1mg	$32	2024-03-01	Buy
Cayman Chemical	25925	BAY-6035	2247890-13-5	5mg	$109	2024-03-01	Buy
Cayman Chemical	25925	BAY-6035	2247890-13-5	10mg	$199	2024-03-01	Buy
Tocris	6561	BAY6035 ≥98%(HPLC)	2247890-13-5	25	$360	2021-12-16	Buy
AK Scientific	0867EN	(2S)-1-(3-Azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide	2247890-13-5	1mg	$133	2021-12-16	Buy

Product number	Packaging	Price	Buy
25925	1mg	$32	Buy
25925	5mg	$109	Buy
25925	10mg	$199	Buy
6561	25	$360	Buy
0867EN	1mg	$133	Buy

BAY-6035 Chemical Properties,Uses,Production

Description

BAY 6035 is a potent and selective SMYD3 inhibitor.

in vitro

BAY-6035 specifically inhibited the methylation of MAP3K2 by SMYD3 in a cellular mechanistic assay with an IC50 <100 nM._x000D_ _x000D_ Reference: SLAS Discov. 2021 Jun 21:24725552211019409. https://journals.sagepub.com/doi/10.1177/24725552211019409?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

target

BAY-6035 is a SMYD3 inhibitor.

storage

Store at -20°C

BAY-6035 Preparation Products And Raw materials

Raw materials

Preparation Products

BAY-6035 Suppliers

Global( 25)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9634	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Anqing YanZhi Pharma Discovery Co.,Ltd.	18055651951	2272561977@qq.com	China	507	58
Finetech Industry Limited	027-87465837 19945049750	sales@finetechnology-ind.com	China	9634	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4153	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9767	58
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29796	68

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Finetech Industry Limited	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Anqing YanZhi Pharma Discovery Co.,Ltd.	58
Finetech Industry Limited	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Chaolan Chemical Technology Center	58
Beijing Solarbio Science & Tecnology Co., Ltd.	68

BAY-6035 Spectrum

BAY-6035(2247890-13-5)¹HNMR

BAY-6035 1H-1,5-Benzodiazepine-7-carboxamide, 1-(3-azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-, (2S)- inhibit,BAY-6035,Histone Methyltransferase,MEKK2,BAY6035,Inhibitor,BAY 6035,SMYD3,methylation (2S)-1-(3-azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide (2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide (2S)-1-(3-Azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-7-carboxamide 2247890-13-5