Metroprolol succinate
- CAS No.
- 98418-47-4
- Chemical Name:
- Metroprolol succinate
- Synonyms
- Selozok;Toprol XL;rolol succinate;METOPROLOL SUCCINATE;metroprolol succinate;Maetaprolol succinate;Metoprolol Succinate (200 mg);Metoprolol Succinate (ToprolX);Metoprolol Succinate (1441298);Metroprolol succinate USP/EP/BP
- CBNumber:
- CB3686041
- Molecular Formula:
- 2C15H25NO3.C4H6O4
- Molecular Weight:
- 652.82
- MDL Number:
- MFCD07391179
- MOL File:
- 98418-47-4.mol
- MSDS File:
- SDS
| Melting point | 136-138°C |
|---|---|
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | Freely soluble in water, soluble in methanol, slightly soluble in ethanol (96 per cent), very slightly soluble in ethyl acetate. |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | RGHAZVBIOOEVQX-UHFFFAOYSA-N |
| FDA UNII | TH25PD4CCB |
Metroprolol succinate price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2511 | Metoprolol succinate Pharmaceutical Secondary Standard; Certified Reference Material | 98418-47-4 | 500MG | $334 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1441298 | Metoprolol succinate United States Pharmacopeia (USP) Reference Standard | 98418-47-4 | 200mg | $857 | 2024-03-01 | Buy |
| Cayman Chemical | 15429 | Metoprolol (succinate) | 98418-47-4 | 25mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 15429 | Metoprolol (succinate) | 98418-47-4 | 250mg | $807 | 2024-03-01 | Buy |
| Cayman Chemical | 15429 | Metoprolol (succinate) | 98418-47-4 | 50mg | $222 | 2024-03-01 | Buy |
Metroprolol succinate Chemical Properties,Uses,Production
Antihypertensives
At present, it is a selective β1 receptor blocker which is widely used for high blood pressure, coronary heart disease, chronic heart failure and cardiac arrhythmia treatment,Metroprolol succinate is a conventional tablet of metoprolol , its elimination half-life is shorter than others, about 3 to 4 hours, so the plasma drug concentration fluctuation is great, and2 to 4 times daily medication is necessary. To overcome these disadvantages, AstraZeneca's recently introduced metoprolol succinate sustained-release tablet is a new depot metoprolol , once-daily medication can guarantee 24 hours of constant metoprolol plasma concentration and β1-receptor blocking effect .On clinical pharmacology and therapeutics ,it has many advantages. Clinically it is used for the treatment of hypertension, angina pectoris, chronic heart failure with left ventricular systolic dysfunction and stable symptoms.
Oral, once a day, take preferably in the morning, it can be broken apart and taken, but you can not chew or crush,at least half a cup of liquid should be taken for delivery . At the same time food intake does not affect their bioavailability. Dosage should be individualized to avoid bradycardia. The following is an effective medication guide: high blood pressure: 47.5~95mg, once daily. Taking 95mg of metoprolol succinate sustained-release tablets may be ineffective in patients ,combine them with other anti-hypertensive drugs, preferably diuretics and dihydropyridine calcium antagonists, or increase the dose. Angina: 95~190mg, once daily.Combine them with nitrates or increase the dose if it is needed.
The above information is edited by the chemicalbook of Tian Ye.
Uses
High blood pressure medication.
Chemical Properties
White or almost white, crystalline powder.
Uses
Anti - hypertensives
Uses
Metoprolol Succinate is used in the treatment of patients suffering from chronic heart failure, as well as to treat blood pressure from mild hypertension. β-adrenoceptor antagonist or β-blocker.
Definition
ChEBI: Metoprolol succinate is an alcohol and a member of phenols.
brand name
Toprol (AstraZeneca).
Metroprolol succinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 | 2691956269@qq.com | China | 359 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Rixing Chemical CO.,LTD | +86-13237129059 -13237129059 | sales@rixingchemi.com | CHINA | 229 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Metroprolol succinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-19 | Metoprolol Succinate
98418-47-4
|
US $0.00-0.00 / KG | 1KG | 99 | 10 tons | Shanghai Affida new material science and technology center | |
 |
2023-09-13 | Metroprolol succinate
98418-47-4
|
US $50.00 / kg | 1kg | 0.99 | 10000 | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-02-23 | Metroprolol succinate
98418-47-4
|
US $67.00 / kg | 1kg | 99% | 5000 tons | Hebei Duling International Trade Co. LTD |
-
- Metoprolol Succinate
98418-47-4
- US $0.00-0.00 / KG
- 99
- Shanghai Affida new material science and technology center
-
- Metroprolol succinate
98418-47-4
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Metroprolol succinate
98418-47-4
- US $67.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD