N,N-Dimethyl-5-methoxytryptamine
- CAS No.
- 1019-45-0
- Chemical Name:
- N,N-Dimethyl-5-methoxytryptamine
- Synonyms
- ct4334;MeODMT;CT 4334;5-OME-DMT;5-MEO-DMT;NSC 88624;5-METHOXY-DMT;Methoxybufotenin;Methylbufotenine;O-Methylbufotenine
- CBNumber:
- CB3720444
- Molecular Formula:
- C13H18N2O
- Molecular Weight:
- 218.29
- MDL Number:
- MFCD00005658
- MOL File:
- 1019-45-0.mol
| Melting point | 69 °C |
|---|---|
| Boiling point | 358.99°C (rough estimate) |
| Density | 1.0346 (rough estimate) |
| refractive index | 1.6450 (estimate) |
| storage temp. | 0-6°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 16.94±0.30(Predicted) |
| form | Solid |
| color | Pale Beige |
| Water Solubility | PRACTICALLY INSOLUBLE |
| CAS DataBase Reference | 1019-45-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | X0MKX3GWU9 |
| NIST Chemistry Reference | 1H-Indole-3-ethanamine, 5-methoxy-N,N-dimethyl-(1019-45-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H332 | |||||||||
| Precautionary statements | P261-P271-P304+P340-P312 | |||||||||
| Hazard Codes | C,Xn | |||||||||
| Risk Statements | 20-34-43-21/22 | |||||||||
| Safety Statements | 22-26-28A-36/37/39-45-36-24/25 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| RTECS | NL7380000 | |||||||||
| HS Code | 29339980 | |||||||||
| NFPA 704 |
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N,N-Dimethyl-5-methoxytryptamine Chemical Properties,Uses,Production
Description
Obtained from Desmodium pulchellum Benth ex Baker, and also from Phalaris tuberosa L., this indole alkaloid is best crystallized from Et20-light petroleum when it yields colourless rectangular plates. It is optically inactive and the ultraviolet spectrum has absorption maxima at 224, 277 and 296 mil. It forms a crystalline picrate as orange-yellow needles, m.p. 176-7°C and the methiodide, m.p. 181-2°C.
Chemical Properties
off-white to slightly yellow crystalline powder
Uses
Hallucinogen; non-selective serotonin receptor agonist
Uses
5-Methoxy-N,N-dimethyltryptamine is a tryptamine derivative and a full potent agonist used in the study of mammalian hormones to stimukate cAMP formation by colliculi neurons and mediate serotoninergic receptors. It is a natural hallucinogen component of Ayahuasca, an Amazonian beverage and is currently being made as a designer drug.
Definition
ChEBI: A tryptamine alkaloid that is N,N-dimethyltryptamine substituted by a methoxy group at position 5.
References
Culvenor, Brown, Smith., Austral. J. Chern., 17, 1301 (1964)
Ghosal, Mukherjee., Chern. Ind., 793 (1965)
Ghosal, Mukherjee., J. Org. Chern., 31, 2284 (1966)