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tert-Butyldimethylsilyl chloride

CAS No. 18162-48-6
Chemical Name: tert-Butyldimethylsilyl chloride
CBNumber: CB3763003
Molecular Formula: C6H15ClSi
Formula Weight: 150.72
MOL File: 18162-48-6.mol
tert-Butyldimethylsilyl chloride Property
Melting point : 86-89 °C
Boiling point : 125 °C(lit.)
density : 0.87 g/mL at 20 °C(lit.)
refractive index : n20/D 1.46
Fp : 73 °F
storage temp. : Store at 5°C
form : Liquid
color : Clear colorless
Water Solubility : Soluble in chloroform and ethyl acetate. Insoluble in water.
Sensitive : Moisture Sensitive
BRN : 505999
CAS DataBase Reference: 18162-48-6(CAS DataBase Reference)
NIST Chemistry Reference: Silane, chloro(1,1-dimethylethyl)dimethyl-(18162-48-6)
EPA Substance Registry System: Silane, chloro(1,1-dimethylethyl)dimethyl- (18162-48-6)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes : C,F,T,Xn
Risk Statements : 22-35-40-34-10-19-11-67-65-63-48/20-20/21/22-45-23/24/25-37-36/37/38
Safety Statements : 26-36/37/39-46-62-45-25-16-28-27-33-29-53-36/37
RIDADR : UN 2925 4.1/PG 2
WGK Germany : 2
RTECS : VV2000000
F : 10-21
Hazard Note : Flammable/Corrosive/Moisture Sensitive
TSCA : Yes
HazardClass : 4.1
PackingGroup : III
HS Code : 29310095
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H228 Flammable solid Flammable solids Category 1
Category 2
P210, P240,P241, P280, P370+P378
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H304 May be fatal if swallowed and enters airways Aspiration hazard Category 1 Danger
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P309 IF exposed or if you feel unwell:
P310 Immediately call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

tert-Butyldimethylsilyl chloride Chemical Properties,Usage,Production

Chemical Properties
White solid
Used to protect alcohols during organic synthesis.
ChEBI: A silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a derivatisation agent used in gas chromatography/mass spectrometry ap lications.
tert-Butyldimethylsilyl chloride Preparation Products And Raw materials
Raw materials
TERT-BUTYLLITHIUM Pentane Dichlorodimethylsilane
Preparation Products
beta-Methyl vinyl phosphate (MAP) (3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one 2-Chloro-4-nitrophenyl-alpha-L-fucopyranoside Calcipotriene Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester 2-CYANOPYRIDINE-4-CARBOXALDEHYDE 4-Mercaptophenylboronic acid Montelukast 4-(HYDROXYMETHYL)PICOLINITRILE 5-(AMINOMETHYL)-1-METHYLPYRROLIDIN-2-ONE Simvastatin
tert-Butyldimethylsilyl chloride Suppliers      Global( 390)Suppliers     
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd. +86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19953 60
Henan DaKen Chemical CO.,LTD. +86-371-55541817 CHINA 2888 58
Shenzhen Sendi Biotechnology Co.Ltd. 0755-23311925 18102838259
0755-23311925 CHINA 3230 55
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30314 84
Suzhou Highfine Biotech Co., Ltd +86-512-68071238 69209928 86880809 68311833
+86-512-68417696 China 493 75
Thermo Fisher Scientific 800-810-5118
+86-10-84193589 China 17579 75
Credit-Chem Co., Ltd. 400-821-5857 021-64326257
021-64393586 QQ;2798200800 China 5277 58
Nanjing Lanya Chemical Co., Ltd. +86-25-8331-5620
+86-25-8331-5629 China 438 55
Shanghai Macklin Biochemical Co.,Ltd. 15221275939
021-51821727 China 13254 55
Taizhou Jinghao Chemical Co., Ltd. 86-576-88550069 13486888296
+86 (576) 8855-7772 China 20 55
18162-48-6(tert-Butyldimethylsilyl chloride)Related Search:
2-Chloro-2-methylpropane Triethylsilane Fattyalkyl dimethyl amine Pivaloyl chloride Chloro(chloromethyl)dimethylsilane Ammonium chloride Potassium chloride Dimethyl phthalate Dimethyl sulfate DI-TERT-BUTYLDICHLOROSILANE Dimethyl sulfide Dimethyl sulfoxide ETHANE Calcium chloride Choline chloride CHLORIDE STANDARD Dimethyl carbonate Dichlorodimethylsilane
BDCS BDCS SILYLATION REAGENT 18162-48-6 Protection and Derivatization Protecting and Derivatizing Reagents Silicon-Based Synthetic Reagents CB2790 chloro(1,1-dimethylethyl)dimethyl-silan chloro(1,1-dimethylethyl)dimethyl-Silane chloro-tert-butyldimethyl-silan Chloro-tert-butyldimethylsilane Dimethyl-tert-butylchlorosilane Silane, chloro-tert-butyldimethyl- Silane, t-butylchlorodimethyl- tbdmschloride t-butylchlorodimethyl-silan SILANE TBM2 SILANE, CHLORO(1,1-DIMETHYLETHYL)DIMETHYL- T-BUTYLDIMENHYLSILYL CHLORIDE t-butyl dimethyl chlorsilane T-BUTYLDIMETHYLCHLOROSILANE T-BUTYLDIMETHYLSILYL CHLORIDE TBDMSCI TBDMSCL TBDMCl TBDMCS TBUME2SI-CL TBSCL TERT-BUTYLDIMETHYLSILYL CHLORIDE TERT-BUTYLDIMETHYLCHLOROSILANE TERT-BUTYLCHLORODIMETHYLSILANE Silylation (GC Derivatizing Reagents) Si (Classes of Silicon Compounds) Monochlorosilanes DNA / RNA Synthesis Si-Cl Compounds GC Derivatizing Reagents Reagents for Oligosaccharide Synthesis Protecting Agents for Hydroxyl Group (DNA/RNA Synthesis) Alkyldimethylsilylation (GC Derivatizing Reagents) Protection & Derivatization Reagents (for Synthesis) Silicon Compounds (for Synthesis) T-butyldimethylsilyl chloride*crystalline tert-Butyldimethylsilyl chloride~TBDMSCl~TBSCl tert-Butyl Dimethylchlorosilane (TBDMSCl) chloro-dimethyl-tert-butyl-silane TERT-BUTYLDIMETHYLSILYL CHLORIDE, 50 WT. % SOLUTION IN TOLUENE TERT-BUTYLDIMETHYLCHLOROSILANE SOLUTION, ~50% IN TOLUENE TERT-BUTYLDIMETHYLCHLOROSILANE SOLUTION, 50% IN METHYL. CHL. TERT-BUTYLDIMETHYLSILYL CHLORIDE, 1.0M S OLUTION IN DICHLOROMETHANE TERT-BUTYLDIMETHYLCHLOROSILANE SOLUTION, ~1 M IN THF TERT-BUTYLCHLORODIMETHYLSILANE SOLUTION TERT-BUTYLDIMETHYLSILYL CHLORIDE, 1.0M S OLUTION IN TETRAHYDROFURAN TERT-BUTYLDIMETHYLCHLOROSILANE 98+% TERT-BUTYLDIMETHYLSILYL CHLORIDE (TBDMSCL) Tert-Butyldimethylchlorosilane50%W/WInToluene Tertbutyldimethylchlorosilane,ProtectiveReagent,
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