Erythorbic Acid
- CAS No.
- 89-65-6
- Chemical Name:
- Erythorbic Acid
- Synonyms
- D-ISOASCORBIC ACID;(5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one;ISOASCORBIC ACID;ERYTHORBATE;araboascorbicacid;D-ARABOASCORBIC ACID;d-arabino-ascorbicacid;Ascorbic Acid EP Impurity F;2,3-didehydro-d-erythro-hexono-1,4-lactone;mercate5
- CBNumber:
- CB3777943
- Molecular Formula:
- C6H8O6
- Molecular Weight:
- 176.12
- MDL Number:
- MFCD00005378
- MOL File:
- 89-65-6.mol
- MSDS File:
- SDS
| Melting point | 169-172 °C (dec.) (lit.) |
|---|---|
| Boiling point | 227.71°C (rough estimate) |
| alpha | -17.25 º (c=10, H2O 25 ºC) |
| Density | 1.3744 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | -17.5 ° (C=10, H2O) |
| FEMA | 2410 | ERYTHROBIC ACID |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear, colorless to very faintly yellow |
| pka | 4.09±0.10(Predicted) |
| form | Crystals or Crystalline Powder |
| color | White to slightly yellow |
| Odor | odorless |
| optical activity | [α]25/D 16.8°, c = 2 in H2O |
| Water Solubility | 1g/10mL |
| Merck | 14,5126 |
| BRN | 84271 |
| Stability | Stable. Combustible. Incompatible with chemically active metals, aluminium, zinc, copper, magnesium, strong bases, strong oxidizing agents. |
| InChIKey | CIWBSHSKHKDKBQ-JLAZNSOCSA-N |
| LogP | -1.69 at 25℃ |
| FDA 21 CFR | 182.3041; 582.3041; 175.105 |
| Substances Added to Food (formerly EAFUS) | ERYTHORBIC ACID |
| SCOGS (Select Committee on GRAS Substances) | Erythorbic acid (D-isoascorbic acid) |
| CAS DataBase Reference | 89-65-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 311332OII1 |
| EPA Substance Registry System | Isoascorbic acid (89-65-6) |
| Cosmetics Info | Erythorbic Acid |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | KF3015000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
Erythorbic Acid price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W241008 | D-(?)-Isoascorbic acid FG | 89-65-6 | 1kg | $72.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | W241008 | D-(?)-Isoascorbic acid FG | 89-65-6 | 5kg | $282 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2418 | AscorbicAcidImpurityF PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial | 89-65-6 | 100MG | $400 | 2024-03-01 | Buy |
| Sigma-Aldrich | 856061 | D-(?)-Isoascorbic acid 98% | 89-65-6 | 100g | $30.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1241823 | Erythorbic acid United States Pharmacopeia (USP) Reference Standard | 89-65-6 | 50mg | $424 | 2024-03-01 | Buy |
Erythorbic Acid Chemical Properties,Uses,Production
Chemical Properties
Erythorbic acid occurs as a white or slightly yellow-colored crystals or powder. It gradually darkens in color upon exposure to light.
Uses
Antioxidant (industrial and food), especially in brewing industry, reducing agent in photography.
Uses
Erythorbic Acid is used as a food additive as an antimicrobial and antioxidative agent.
Uses
Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150–200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%.
Definition
ChEBI: D-isoascorbic acid is an ascorbic acid.
Production Methods
Erythorbic acid is synthesized by the reaction between methyl 2- keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose, and produced from Penicillium spp.
Biotechnological Production
Yeasts and other fungi synthesize the C5 sugar acid D-erythroascorbic acid which shares structural and physicochemical properties with Asc. D-erythroascorbic acid serves similar protective functions in these microorganisms as Asc does in plants and animals, including the scavenging of reactive oxygen species. The biosynthesis of D-erythroascorbic acid starts from D-arabinose obtained by the microorganism from decaying plant material. D-arabinose, presumably in its 1,4-furanosidic isomeric form, is oxidized by NAD(P)+ specific dehydrogenases to D-arabinono-1,4-lactone, which is further oxidized to D-erythroascorbic acid by D-arabinono-1,4-lactone oxidase. Resting cells of Saccharomyces cerevisiae can synthesize Asc from L-galactose, L-galactono-1,4-lactone, or L-gulono- 1,4-lactone via the pathway naturally used for D-erythroascorbic acid.
Flammability and Explosibility
Non flammable
Pharmaceutical Applications
Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of L-ascorbic acid.
Safety
Erythorbic acid is widely used in food applications as an
antioxidant. It is also used in oral pharmaceutical applications as
an antioxidant. Erythorbic acid is generally regarded as nontoxic
and nonirritant when used as an excipient. Erythorbic acid is readily
metabolized and does not affect the urinary excretion of ascorbic
acid.
The WHO has set an acceptable daily intake of erythorbic acid
and its sodium salt in foods at up to 5 mg/kg body-weight.
storage
Erythorbic acid should be stored in an airtight container, protected from light, in a cool, dry place.
Purification Methods
Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.]
Incompatibilities
Erythorbic acid is incompatible with chemically active metals such as aluminum, copper, magnesium, and zinc. It is also incompatible with strong bases and strong oxidizing agents.
Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral concentrate and tablets).
Erythorbic Acid Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd. | +86-0086-025-69916489 +86-18852044786 | tongyuansales@vip.sina.com | China | 323 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
View Lastest Price from Erythorbic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | Erythorbic Acid
89-65-6
|
US $0.00-0.00 / KG | 1KG | 99% | 66000kg/Month | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2023-08-09 | Erythorbic Acid
89-65-6
|
US $0.00-0.00 / kg | 1kg | 0.99 | 50000kg | Hebei Yibangte Import and Export Co. , Ltd. | |
 |
2023-04-04 | Erythorbic Acid
89-65-6
|
US $11.00 / bag | 1bag | 99-100% | 10T | Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd. |
-
- Erythorbic Acid
89-65-6
- US $0.00-0.00 / KG
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Erythorbic Acid
89-65-6
- US $0.00-0.00 / kg
- 0.99
- Hebei Yibangte Import and Export Co. , Ltd.
-
- Erythorbic Acid
89-65-6
- US $11.00 / bag
- 99-100%
- Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
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