ChemicalBook >> CAS DataBase List >>6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6-CHLORO-2-PICOLINIC ACID METHYL ESTER
- CAS No.
- 6636-55-1
- Chemical Name:
- 6-CHLORO-2-PICOLINIC ACID METHYL ESTER
- Synonyms
- AKOS BBS-00004651;Sorafenib Impurity 117;methyl 6-chloropicolinate;6-Chloropicolinic acid methyl ester;methyl (6-chloropyridin-2-yl)acetate;methyl 6-chloro-2-pyridinecarboxylate;METHYL 6-CHLOROPYRIDINE-2-CARBOXYLATE;2-chloropyridine-6-carboxylate methyl;methyl 2-(6-chloropyridin-2-yl)acetate;6-CHLORO-2-PICOLINIC ACID METHYL ESTER
- CBNumber:
- CB3780710
- Molecular Formula:
- C7H6ClNO2
- Molecular Weight:
- 171.58
- MDL Number:
- MFCD00155391
- MOL File:
- 6636-55-1.mol
- MSDS File:
- SDS
Last updated:2024-04-09 22:15:29
| Melting point | 93-94° |
|---|---|
| Boiling point | 275.8±20.0 °C(Predicted) |
| Density | 1.294±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -1.03±0.10(Predicted) |
| form | Solid |
| color | Pale yellow |
| Water Solubility | Slightly soluble in water. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
6-CHLORO-2-PICOLINIC ACID METHYL ESTER price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2640 | Methyl 6-Chloro-2-pyridinecarboxylate >98.0%(GC) | 6636-55-1 | 1g | $16 | 2024-03-01 | Buy |
| TCI Chemical | M2640 | Methyl 6-Chloro-2-pyridinecarboxylate >98.0%(GC) | 6636-55-1 | 5g | $31 | 2024-03-01 | Buy |
| Alfa Aesar | H64023 | Methyl 6-chloropyridine-2-carboxylate, 95% | 6636-55-1 | 5g | $47.7 | 2024-03-01 | Buy |
| Alfa Aesar | H64023 | Methyl 6-chloropyridine-2-carboxylate, 95% | 6636-55-1 | 25g | $177 | 2024-03-01 | Buy |
| Alfa Aesar | H64023 | Methyl 6-chloropyridine-2-carboxylate, 95% | 6636-55-1 | 100g | $484 | 2021-12-16 | Buy |
6-CHLORO-2-PICOLINIC ACID METHYL ESTER Chemical Properties,Uses,Production
Uses
Methyl 6-chloropyridine-2-carboxylate was coupled with 2-(trimethylstannyl)pyridine to afford methyl 2,2?-bipyridine-6-carboxylate.
Synthesis Reference(s)
Synthetic Communications, 14, p. 77, 1984 DOI: 10.1080/00397918408060867
Synthesis
6-Chloro-2-picolinic acid methyl ester is prepared by the reaction of methanol and 6-Chloropicolinic acid. The specific synthesis steps are as follows:
Add thionyl chloride (3.7 ml, 50.8 mmol) to a solution of 6-chloropicolinic acid (4.0 g, 25.4 mmol) in methanol (85 ml) at 0 C. Stir the resultant solution for 15 minutes at 0 C, 0.5 hours at room temperature, and 6 hours at 50 C. Concentrate the reaction in vacuo and dilute with CHCl3 (150ml). Wash the organic solution with saturated aqueous sodium bicarbonate (3 x 100 ml), and brine (1 x 100 ml) and dry with sodium sulfate. Filtration and concentration afford methyl 6-chloropicolinate 4.38 g (100 percent) as a white solid. 1H NMR (CDCl3): δ 8.05 (m, 1H), 7.73 (m, 1H), 7.42 (m, 1H), 3.95 (s, 3H).
6-CHLORO-2-PICOLINIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 212)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7933 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
View Lastest Price from 6-CHLORO-2-PICOLINIC ACID METHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-09 | 6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6636-55-1
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2022-10-11 | 6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6636-55-1
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-10-26 | 6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6636-55-1
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6636-55-1
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6636-55-1
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6636-55-1
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
6636-55-1(6-CHLORO-2-PICOLINIC ACID METHYL ESTER)Related Search:
6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
METHYL 6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE
Methyl 6-bromonicotinate
METHYL 6-FORMYLNICOTINATE
methyl 6-chloropyrimidine-4-carboxylate
Methyl 6-bromoisoquinoline-1-carboxylate
Methyl 6-bromohexanoate
Methyl 6-chloronicotinate
METHYL 6-CHLOROPYRIDAZINE-3-CARBOXYLATE
methyl 6-methylpyridine-2-carboxylate
1of4
Methyl 6-Chloropyridine-2-carboxylate, 97+%
METHYL 6-CHLOROPYRIDINE-2-CARBOXYLATE
AKOS BBS-00004651
6-CHLOROPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
6-CHLORO-2-PICOLINIC ACID METHYL ESTER
6-Chloro-2-pyridinecarboxylic acid methyl ester
6-Chloropicolinic acid methyl ester
2-Pyridinecarboxylic acid, 6-chloro-, methyl ester
methyl 6-chloro-2-pyridinecarboxylate
methyl 2-(6-chloropyridin-2-yl)acetate
methyl 6-chloropicolinate
methyl (6-chloropyridin-2-yl)acetate
2-chloropyridine-6-carboxylate methyl
6-chloro-2-picolonic acid methyl ester
Methyl 6-chloropicolinate, 2-Chloro-6-(methoxycarbonyl)pyridine
6-Chloro-2-picolinic acid methyl ester Solution
Methyl 6-Chloro-2-pyridinecarboxylate >
Methyl6-chloropyridine-2-carboxylate,95%
6-CHLORO-2-PICOLINIC ACID METHYL ESTER ISO 9001：2015 REACH
Sorafenib Impurity 117
6636-55-1
Picolinic acid series