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JAK3 INHIBITOR VI

JAK3 INHIBITOR VI structure

CAS No.: 856436-16-3

Chemical Name:: JAK3 INHIBITOR VI

Synonyms: JI6;JAK3 INHIBITOR VI

CBNumber:: CB3787012

Molecular Formula:: C19H17N3O4S

Molecular Weight:: 383.42098

MDL Number:: MFCD09037543

MOL File:: 856436-16-3.mol

Last updated:2023-09-04 15:51:00

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JAK3 INHIBITOR VI Properties

storage temp.	+2C to +8C
form	Yellow solid
FDA UNII	PJ7TZW55W9

JAK3 INHIBITOR VI price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	420126	JAK3 Inhibitor VI - CAS 856436-16-3 - Calbiochem	856436-16-3	5MG	$195	2023-06-20	Buy

Product number	Packaging	Price	Buy
420126	5MG	$195	Buy

JAK3 INHIBITOR VI Chemical Properties,Uses,Production

General Description

A cell-permeable, potent, and reversible inhibitor of Janus kinase 3 (JAK3) (IC₅₀ = 27 nM). Reported to bind to the enzyme active site and prevent IL-2-induced phosphorylation of JAK3 and STAT5. Also reported to inhibit IL-2-induced cell proliferation (IC₅₀ = 760 nM for murine CTLL cells and 250 nM for human T-cells). Shown to alleviate oxazolone-induced ear edema in mice with an efficacy comparable to Dexamethasone (Cat. No. 265005) and displays ~16-fold greater selectivity over JAK2.

Biochem/physiol Actions

Cell permeable: yes

JAK3 INHIBITOR VI Preparation Products And Raw materials

Raw materials

Preparation Products

JAK3 INHIBITOR VI Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3412	55
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1249	58

Supplier	Advantage
Sigma-Aldrich	80
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Beijing Biocreative Technology Co., Ltd.	58

JAK3 INHIBITOR VI Spectrum

JAK3 INHIBITOR VI(856436-16-3)¹HNMR

JAK3 INHIBITOR VI JI6 856436-16-3