rifamide
- CAS No.
- 2750-76-7
- Chemical Name:
- rifamide
- Synonyms
- M/14;rifamide;Rifomide;Rifamycin M-14;Rifomycin M-14;rifamide USP/EP/BP;Rifamycin B diethylamide;Rifomycin B diethylamide;Rifamycin, 4-O-[2-(diethylamino)-2-oxoethyl]-
- CBNumber:
- CB3908402
- Molecular Formula:
- C43H58N2O13
- Molecular Weight:
- 810.93
- MDL Number:
- MOL File:
- 2750-76-7.mol
| Melting point | 170°C (rough estimate) |
|---|---|
| Boiling point | 755.63°C (rough estimate) |
| alpha | D20 -48.7° (c = 0.4 in methanol) |
| Density | 1.1791 (rough estimate) |
| refractive index | 1.4670 (estimate) |
| FDA UNII | TS121H7U7E |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P |
| Toxicity | LD50 in mice, rats (mg/kg): 2450, >4000 orally; 640, 2500 s.c.; 320, 535 i.p.; 315, 380 i.v. (Dezulian) |
rifamide price
rifamide Chemical Properties,Uses,Production
Uses
Antibacterial.
Pharmaceutical Applications
The diethyl amide of rifamycin B, formulated as the sodium salt for parenteral administration. It exhibits high activity against Gram-positive organisms and M. tuberculosis typical of the group. MICs for Gram-negative bacilli are of the order of 20–50 mg/L.
It is absorbed orally and is rapidly eliminated through the bile, achieving concentrations sufficient to inhibit Gramnegative bacilli. In contrast to rifampicin, it can be administered as the sodium salt by intramuscular injection. A dose of 150 mg produces mean plasma levels of about 1 mg/L. The plasma halflife is about 2 h. The same dosage produces concentrations over 1 g/L in bile and c. 40 mg/L in the gallbladder wall.
Toxicity and side effects are similar to those of other rifamycins. It has been used in staphylococcal infections and infections of the biliary tract. It is unsuitable for the treatment of tuberculosis because of insufficient distribution to the tissues.
rifamide Preparation Products And Raw materials
Raw materials
Preparation Products
rifamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9231 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29016 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Wuhan Sunncell Biotech Co., Ltd. | 17764018385 | 1242926414@qq.com | China | 1840 | 58 |
| Guangzhou Gineo Biotechnology Co., Ltd. | 020-29185636 18802035152 | 3691125803@qq.com | China | 9203 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| Guangzhou Fu'erbo Biological Technology Co.,Ltd. | 19513720913 | 1536198927@qq.com | China | 9100 | 58 |
View Lastest Price from rifamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-06-23 | rifamide USP/EP/BP
2750-76-7
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- rifamide USP/EP/BP
2750-76-7
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited