O-(2,4-dinitrophenyl)hydroxylamine
- CAS No.
- 17508-17-7
- Chemical Name:
- O-(2,4-dinitrophenyl)hydroxylamine
- Synonyms
- 2,4-Dinitrophenylhydroxylamine;NSC 148499;2,4-NitrophenoxyaMine;2,4-DinitrophenoxyaMine;4-dinitrophenyl)hydroxylamine;1-aMinooxy-2,4-dinitro-benzene;O-(2,4-dinitrophenyl)hydroxylamine;HydroxylaMine,O-(2,4-dinitrophenyl)-;O-(2,4-Dinitrophenyl)hydroxylamine,98%;TIANFUCHEM--17508-17-7---O-(2,4-dinitrophenyl)hydroxylamine
- CBNumber:
- CB3922714
- Molecular Formula:
- C6H5N3O5
- Molecular Weight:
- 199.12
- MDL Number:
- MFCD00075001
- MOL File:
- 17508-17-7.mol
- MSDS File:
- SDS
| Melting point | 112.5°C |
|---|---|
| Boiling point | 336.62°C (rough estimate) |
| Density | 1.6937 (rough estimate) |
| refractive index | 1.6910 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | solid |
| pka | -1.07±0.70(Predicted) |
| color | yellow |
| FDA UNII | I1308NOV00 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| TSCA | No | |||||||||
| HS Code | 29221990 | |||||||||
| NFPA 704 |
|
O-(2,4-dinitrophenyl)hydroxylamine price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5103 | O-(2,4-Dinitrophenyl)hydroxylamine | 17508-17-7 | 1G | $81 | 2024-03-01 | Buy |
| TCI Chemical | D5103 | O-(2,4-Dinitrophenyl)hydroxylamine | 17508-17-7 | 5G | $282 | 2024-03-01 | Buy |
| TRC | D479985 | O-(2,4-Dinitrophenyl)hydroxylamine | 17508-17-7 | 5g | $110 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22435 | O-(2,4-Dinitrophenyl)hydroxylamine | 17508-17-7 | 5G | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22435 | O-(2,4-Dinitrophenyl)hydroxylamine | 17508-17-7 | 10g | $200 | 2021-12-16 | Buy |
O-(2,4-dinitrophenyl)hydroxylamine Chemical Properties,Uses,Production
Chemical Properties
Light yellow solid
Uses
O-(2,4-Dinitrophenyl)hydroxylamine is a rapid active-site-directed inhibitor of D-amino acid oxidase; modification results in specific incorporation of an amine group into an accessible nucleophilic r esidue with concomitant release of 2,4-dinitrophenol.
Uses
Efficient agent for metal-free amination of arylboronic acids leading to primary anilines. Reagents used in Rhodium-catalyzed aziridines formation.
Preparation
To a stirred solution of 13.3 gm (0.1 mole) of t-butyl JV-hydroxycar-bamate and 5.6 gm (0.1 mole) of potassium hydroxide in 200 ml of absolute ethanol is added 20.2 gm (0.1 mole) of 2,4-dinitrochlorobenzene. The resultant deep red solution is stirred at room temperature for 1 hr; then enough glacial acetic acid is added dropwise to produce a light yellow solution. The solution is poured into 1.5 liters of cold water. The yellow oil which separates is gradually converted to crystals. The solid ?-butyl JV-(2,4-dinitrophenoxy)carbamate is separated, dried, and recrystallized from an ethyl acetate-hexane mixture to afford 16.4 gm (53%), m.p. 74-75°C. To 15 ml of trifluoroacetic acid is added 4 gm (0.0133 mole) of the i-butyl J/V-(2,4-dinitrophenoxy)carbamate. After the evolution of carbon dioxide has subsided, the solution is poured into 100 ml of ice water. The resultant oily layer crystallizes on standing to afford 2.5 gm (95%), m.p. 112°C (from ethanol).
Recently it was discovered that the alkylation of ethyl JV-hydroxy-carbamate under alkaline conditions, particularly in a DMF medium at 60°C in the presence of sodium bicarbonate, leads to the ultimate formation of O-alkylated hydroxylamines. On the other hand, at 80-85°C, the direct alkylation without the presence of a base ultimately leads to N-alkylhydrox-ylamines (see Table I) [59]. The reaction of ethylazidoformate with an alcohol, while perhaps hazardous, may have some merit (Eqs. 31-33). The overall yield, based on ethyl chloroformate, is said to be on the order of 60%.
O-(2,4-dinitrophenyl)hydroxylamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
View Lastest Price from O-(2,4-dinitrophenyl)hydroxylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-01-31 | O-(2,4-dinitrophenyl)hydroxylamine
17508-17-7
|
US $100.00 / kg | 1kg | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2022-09-14 | O-(2,4-dinitrophenyl)hydroxylamine
17508-17-7
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-07-13 | O-(2,4-dinitrophenyl)hydroxylamine
17508-17-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- O-(2,4-dinitrophenyl)hydroxylamine
17508-17-7
- US $100.00 / kg
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- O-(2,4-dinitrophenyl)hydroxylamine
17508-17-7
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- O-(2,4-dinitrophenyl)hydroxylamine
17508-17-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd