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CATHINE HYDROCHLORIDE

CAS No.
492-39-7
Chemical Name:
CATHINE HYDROCHLORIDE
Synonyms
Katine;C08300;Cathine;psi-Norephedrine;Nor-psi-ephedrine;Pseudonorephedrine;d-Nor-psi-ephedrine;d-norpseudoephedrine;(+)-norpseudoephedrin;NORPSEUDOEPHEDRINE HCL
CBNumber:
CB4116082
Molecular Formula:
C9H13NO
Molecular Weight:
151.21
MDL Number:
MFCD00070245
MOL File:
492-39-7.mol
Last updated:2023-06-08 09:02:12

CATHINE HYDROCHLORIDE Properties

Melting point 77.5-78°
alpha 20546 +37.9° (c = 3 in methanol)
Boiling point 273.23°C (rough estimate)
Density 1.0406 (rough estimate)
refractive index 1.5380 (estimate)
storage temp. 2-8°C
solubility H2O: ~20 mg/mL
pka 8.92(at 25℃)
form solid
color white
optical activity [α]/D +34.0±2.0°, c = 3.5 in ethanol
FDA UNII E1L4ZW2F8O
ATC code A08AA07
EPA Substance Registry System Benzenemethanol, .alpha.-[(1S)-1-aminoethyl]-, (.alpha.S)- (492-39-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P261-P301+P310-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  RC9275000
Toxicity LD50 scu-mus: 275 mg/kg ARZNAD 5,367,55
DEA Controlled Substances CSCN: 1230
CAS SCH: IV
NARC: N
NFPA 704
0
2 0

CATHINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

An enantiomer of phenylpropanolamine and a metabolite of cathinone.

Definition

ChEBI: Cathine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2S-stereoisomer). It has a role as a plant metabolite, a central nervous system stimulant and a psychotropic drug. It is a member of amphetamines and a phenethylamine alkaloid.

brand name

Adiposetten n;Amorphan depot;Andiposetten;Appetrol;Dietene;Exponcit;Insacial;Miniscap;Minusin depot;Mirapront n;Neo-soldana;Novese;Phyteia schlankheitsdragees;Reduform;Redufrom;Thinz.

World Health Organization (WHO)

Cathine, a sympathomimetic amine, was formerly widely available in proprietary anorexic preparations. As dependence can occur and abuse has been reported, cathine has recently (1986) been subjected to control under Schedule III of the 1971 Convention on Psychotropic Substances. (Reference: (UNCPS3) United Nations Convention on Psychotropic Substances (III), , , 1971)

Safety Profile

Poison by subcutaneous route.When heated to decomposition it emits toxic vapors ofNOx.

17097-67-5
492-39-7
Synthesis of CATHINE HYDROCHLORIDE from (4S,5S)-4-Methyl-5-phenyl-2-oxazolidinone

CATHINE HYDROCHLORIDE Preparation Products And Raw materials

D-NORPSEUDOEPHEDRINE HYDROCHLORIDE (+)-NORPSEUDOEPHEDRINE HCL NORPSEUDOEPHEDRINE HCL NORPSEUDOEPHEDRINE HCL, (+)- PSEUDONOREPHEDRINE HYDROCHLORIDE (+)-norpseudoephedrin alpha-(1-aminoethyl)-,[s-(theta,theta)]-benzenemethano Benzenemethanol, alpha-(1-aminoethyl)-, [S-(R*,R*)]- Cathine d-norpseudoephedrine d-Nor-psi-ephedrine Katine Nor-psi-ephedrine Pseudonorephedrine psi-Norephedrine threo-1-Phenyl-1-hydroxy-2-aminopropane threo-2-Amino-1-hydroxy-1-phenylpropane (1S,2S)-2-amino-1-phenylpropan-1-ol C08300 (1S,2S)-D-Norpseudoephedrine base (+)-Cathine, (+)-Pseudonorephedrine, (1S,2S)-2-Amino-1-phenyl-1-propanol, D-(+)-Norpseudoephedrine (1S,2S)-(+)-Norpseudoephedrine Benzenemethanol, α-[(1S)-1-aminoethyl]-, (αS)- (+)-Pseudo Norephedrine 492-39-7