2-Iodophenylacetic acid
- CAS No.
- 18698-96-9
- Chemical Name:
- 2-Iodophenylacetic acid
- Synonyms
- RARECHEM AL BO 1302;2-IODOPHENYLACETIC ACID;O-IODOPHENYLACETIC ACID;2-IodophenylaceticAcid>2-Iodo-benzeneacetic acid;2-(2-iodophenyl)aceticaci;BENZENEACETIC ACID, 2-IODO-;2-(2-IODOPHENYL)ACETIC ACID;2-Iodophenylacetic acid 97%;2-IODOPHENYLACETIC ACID, 97+%
- CBNumber:
- CB4131159
- Molecular Formula:
- C8H7IO2
- Molecular Weight:
- 262.04
- MDL Number:
- MFCD00046546
- MOL File:
- 18698-96-9.mol
- MSDS File:
- SDS
| Melting point | 116-119 °C (lit.) |
|---|---|
| Boiling point | 344.5±17.0 °C(Predicted) |
| Density | 1.885±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | pK1:4.038 (25°C) |
| color | Cream |
| Sensitive | Light Sensitive |
| BRN | 2086800 |
| CAS DataBase Reference | 18698-96-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant/Light Sensitive | |||||||||
| HazardClass | IRRITANT, LIGHT SENSITIVE | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
2-Iodophenylacetic acid price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 531472 | 2-Iodophenylacetic acid 97% | 18698-96-9 | 5g | $41.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 531472 | 2-Iodophenylacetic acid 97% | 18698-96-9 | 25g | $44.4 | 2024-03-01 | Buy |
| TCI Chemical | I0723 | 2-Iodophenylacetic Acid >97.0%(GC)(T) | 18698-96-9 | 5g | $53 | 2024-03-01 | Buy |
| TCI Chemical | I0723 | 2-Iodophenylacetic Acid >97.0%(GC)(T) | 18698-96-9 | 25g | $175 | 2024-03-01 | Buy |
| Alfa Aesar | L15116 | 2-Iodophenylacetic acid, 98+% | 18698-96-9 | 5g | $57.65 | 2024-03-01 | Buy |
2-Iodophenylacetic acid Chemical Properties,Uses,Production
Chemical Properties
Cream powder
Application
2-Iodophenylacetic acid may be used in the preparation of:
2-iodophenylacetyl chloride
3,4-dimethoxyphenyl 2-iodophenylacetate
N-{2-[2-(2-iodophenyl)-acetylamino]-ethyl}-2-(3,4- dichlorophenyl)-acetamide
Uses
2-Iodophenylacetic acid is a synthetic intermediate that is widely used in the chemical, pharmaceutical and cosmetic industries. 2-Iodophenylacetic acid is also used as a reagent to synthesize Cepharanone B, a natural and potentially antineoplastic aristolactam that is found in Piper longum (a medicinal plant native to India).
Preparation
synthesis of 2-Iodophenylacetic acid: The anthranilic acid solution was acidified with sulfuric acid to pH = 1 followed by a diazotization reaction. The diazonium was added dropwise to the potassium iodide-sulfuric acid solution (3.5 g KI, 1.0 mL concentrated H2SO4, 5 mL water) preheated to 60-70 °C, stirred for 30 min, placed overnight, and filtered to obtain the product. Recrystallization with 50% ethanol aqueous solution gave 3.83 g of 2-iodophenylacetic acid, the yield was 73% (calculated as o-nitrophenylacetic acid), and the melting point was 113-115 °C (117 °C reported in the literature).
General Description
2-Iodophenylacetic acid is a substituted acetic acid that can be prepared from 2-iodobenzyl cyanide. It undergoes palladium-catalyzed reaction with allenes to form 1,3-butadienes. 2-Iodophenylacetic acid also undergoes photolysis in carbon tetrachloride to form the corresponding chloro compound.
2-Iodophenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xinchem Co., Ltd. | +86-021-34123252 +8618049800532 | xinchem@xinchem.com | China | 49 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7377 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
View Lastest Price from 2-Iodophenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2023-12-24 | 2-Iodophenylacetic acid
18698-96-9
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-10-22 | 2-Iodophenylacetic acid
18698-96-9
|
US $0.00-0.00 / drums | 1drums | 99%min. | 10tons | Shanghai Xinchem Co., Ltd. | |
 |
2023-04-29 | 2-Iodophenylacetic acid
18698-96-9
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Guanlang Biotechnology Co., Ltd. |
-
- 2-Iodophenylacetic acid
18698-96-9
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Iodophenylacetic acid
18698-96-9
- US $0.00-0.00 / drums
- 99%min.
- Shanghai Xinchem Co., Ltd.
-
- 2-Iodophenylacetic acid
18698-96-9
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.