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licarin B

licarin B structure

CAS No.: 51020-87-2

Chemical Name:: licarin B

Synonyms: licarin B;Licarine B;(-)-Licarin B;5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole;5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole;5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole;1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-;1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI)

CBNumber:: CB41314632

Molecular Formula:: C20H20O4

Molecular Weight:: 324.37

MDL Number:: MFCD13195533

MOL File:: 51020-87-2.mol

Last updated:2023-04-23 13:52:06

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licarin B Properties

Boiling point	428.5±45.0 °C(Predicted)
Density	1.201±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	powder
color	White

licarin B price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ApexBio Technology	N1572	(-)-LicarinB	51020-87-2	20mg	$250	2021-12-16	Buy
AK Scientific	Y1205	licarinB	51020-87-2	25mg	$336	2021-12-16	Buy
Crysdot	CD11113736	LicarinB 97%	51020-87-2	50mg	$353	2021-12-16	Buy
Chemenu	CM161067	5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole 97%	51020-87-2	100mg	$468	2021-12-16	Buy
Crysdot	CD11113736	LicarinB 97%	51020-87-2	100mg	$641	2021-12-16	Buy

Product number	Packaging	Price	Buy
N1572	20mg	$250	Buy
Y1205	25mg	$336	Buy
CD11113736	50mg	$353	Buy
CM161067	100mg	$468	Buy
CD11113736	100mg	$641	Buy

licarin B Chemical Properties,Uses,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from nutmeg, Lauraceae (Lauraceae) Licarin aritu Ducke trunk (yield: 0.35%) Machilus japonica Sieb.et Zucc. Ye Hongnan Machilus thunbergii Sieb.et Zucc. Bark, wood, leaves.

Uses

Licarin B has antibacterial, anti-inflammatory, sedative and anti-tumor effects.

Biological Activity

Licarin B, derived from the seeds of Myristica fragrans, is an inhibitor of NO production and improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway.

in vitro

Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes.

Cell Viability Assay < /p>

Cell Line:	3T3-L1 cell.
Concentration:	1-500 μM.
Incubation Time:	48 h.
Result:	Did not cause significant cell death up to 500 μM concentration.

Cell Viability Assay

td>

Cell Line:	3T3-L1 cell.
Concentration:	5 μM, 10 μM, 15 μM.
Incubation Time:	8 days (replaced every 2 days).	8 days (replaced every 2 days).
Result:	LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation.

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target

PPAR | GLUT | PI3K | Akt | IRS-1

licarin B Preparation Products And Raw materials

Raw materials

Preparation Products

licarin B Suppliers

Global( 123)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Xi'an Kono chem co., Ltd.,	58
Chongqing Chemdad Co., Ltd	58
Shanghai Standard Technology Co., Ltd.	58
Neostar United (Changzhou) Industrial Co., Ltd.	58

View Lastest Price from licarin B manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-02-24	(-)-Licarin B 51020-87-2	US $0.00 / mg	20mg	≥98%(HPLC)	100 g	Shanghai Standard Technology Co., Ltd.
	2019-07-06	licarin B 51020-87-2	US $1.00-1.00 / kg	1 mg	99%	100KG	Career Henan Chemical Co

(-)-Licarin B
51020-87-2
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

licarin B
51020-87-2
US $1.00-1.00 / kg
99%
Career Henan Chemical Co

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1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI) licarin B 5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole 5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole 5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole Licarine B 1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]- (-)-Licarin B 51020-87-2 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract reagent standard substance