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Isothiazolinones

Isothiazolinones Structure
Isothiazolinones structure
CAS No.
26172-55-4
Chemical Name:
Isothiazolinones
Synonyms
CMIT;Isothiazolinone;CMI;CMIT/MIT;5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE;MCI;5-Chloro-2-methyl-3(2H)-isothiazolone;Chloromethylisothiazolinone;5-chloro-2-methyl-2H-isothiazol-3-one;isothiazolin
CBNumber:
CB4132565
Molecular Formula:
C4H4ClNOS
Molecular Weight:
149.6
MDL Number:
MFCD00792550
MOL File:
26172-55-4.mol
MSDS File:
SDS
Last updated:2024-03-14 18:29:10
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Isothiazolinones Properties

Melting point 42-45?C
Boiling point 109.7°C
Density 1.25 (14% aq.)
refractive index n20/D 1.378
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form Liquid
pka -4.06±0.40(Predicted)
Stability Stable. Incompatible with strong oxidizing agents.
LogP 0.240 (est)
Indirect Additives used in Food Contact Substances 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE
CAS DataBase Reference 26172-55-4(CAS DataBase Reference)
FDA UNII DEL7T5QRPN
NIST Chemistry Reference 5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4)
EPA Substance Registry System 5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H317-H319-H412
Precautionary statements  P261-P264-P273-P280-P302+P352-P305+P351+P338
Hazard Codes  C,N,T,Xn
Risk Statements  34-43-50-20/21/22-50/53-23/24/25-42/43
Safety Statements  26-36/37/39-45-60-61-24-28-36/37-23
RIDADR  UN 1760 8/PG 2
WGK Germany  1
RTECS  NX8156850
HazardClass  8
PackingGroup  III
HS Code  3808929090

Isothiazolinones price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1597 CMIT/MIT Pharmaceutical Secondary Standard; Certified Reference Material 26172-55-4 1ml $97.5 2024-03-01 Buy
TRC C369235 5-Chloro-2-methyl-3-isothiazolone 26172-55-4 2.5mg $160 2021-12-16 Buy
Usbiological C5029-26 5-Chloro-2- 26172-55-4 2.5mg $496 2021-12-16 Buy
Usbiological 435989 5-Chloro-2- 26172-55-4 1mg $360 2021-12-16 Buy
Usbiological 161851 5-Chloro-2- 26172-55-4 1g $418 2021-12-16 Buy
Product number Packaging Price Buy
PHR1597 1ml $97.5 Buy
C369235 2.5mg $160 Buy
C5029-26 2.5mg $496 Buy
435989 1mg $360 Buy
161851 1g $418 Buy

Isothiazolinones Chemical Properties,Uses,Production

Description

Isothiazolinone is a heterocyclic chemical compound related to isothiazole. Isothiazolinone is an antimicrobial preservative that is often used to control fungi, bacteria, and algae. Since water-containing solutions are the breeding grounds for bacteria, isothiazolinone can easily be used in such solutions.

Applications

Although isothiazolinones have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials. Notably, various products that use isothiazolinones are in the market, including shampoo, hand sanitizer, and lotions. Isothiazolinones is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.

Safety Information

The recommended use of isothiazolinone products by the manufacturers used as wrinkle releaser is not harmful. However, allergy to skin is one of the most reported issue with isothiazolinone.

Description

Methy1chloro-isothiazolinone (MCI) is contained, along with methylisothiazolinone (MI), in Kathon cosmetic grade (CG) and MCI/MI. It is irritant and sensitizer.

Chemical Properties

Liquid

Uses

A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.

Uses

Isocil(R) RW is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems. Suggested applications: Industrial water treatment. Very low use levels.

Uses

Isocil(R) PC is a cost-effective antimicrobial for personal care formulations. Suggested applications: personal care preservative.

Uses

Isocil(R) MW-14 is a high performance biocide for preserving metal working fluids, hydraulic fluids, polymer emulsions, pigment dispersions. Suggested applications: preservative concentrate. Very low level.

Definition

ChEBI: A 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM.

Isothiazolinones synthesis

999-72-4
26172-55-4
Synthesis of Isothiazolinones from N,N'-Dimethyl-3,3'-dithiodipropionamide

Isothiazolinones Preparation Products And Raw materials

Raw materials

Chlorine Methyl acrylate

Preparation Products

Isothiazolinones Suppliers

Global( 392)Suppliers
Supplier Tel Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418671 sales@tnjchem.com China 34572 58
Suzhou Genemill Biotechnology Co.,Ltd 		+86-0512-65917170; +8615862502491 aimeegao@genemill.com China 39 58
Wuhan Quanjinci New Material Co.,Ltd. 		+8615271838296 kyra@quanjinci.com China 1532 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7786 58
Shandong Juchuang Chemical Co., LTD 		+86-18885615001 +86-18885615001 admin@juchuangchem.com China 387 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
Tianjin Zhongxin Chemtech Co., Ltd. 		+86-022-66880623 +8618622897568 sales@tjzxchem.com China 559 58
Supplier Advantage
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Suzhou Genemill Biotechnology Co.,Ltd 		58
Wuhan Quanjinci New Material Co.,Ltd. 		58
Henan Fengda Chemical Co., Ltd 		58
Shandong Juchuang Chemical Co., LTD 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Hefei TNJ Chemical Industry Co.,Ltd. 		55
Tianjin Zhongxin Chemtech Co., Ltd. 		58

Related articles

View Lastest Price from Isothiazolinones manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isothiazolinones pictures 2024-04-25 Isothiazolinones
26172-55-4
 US $1.00 / g 1g 99 20tons Shanghai Longyu Biotechnology Co., Ltd.
Isothiazolinones pictures 2024-04-15 Isothiazolinones
26172-55-4
 US $1.00 / mg 1000mg 99 5ton/month ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
Isothiazolinones pictures 2024-03-15 Isothiazolinones
26172-55-4
 US $119.00-98.00 / kg 500kg 99.9 200ton Shandong Juchuang Chemical Co., LTD
  • Isothiazolinones pictures
  • Isothiazolinones
    26172-55-4
  • US $1.00 / g
  • 99
  • Shanghai Longyu Biotechnology Co., Ltd.
  • Isothiazolinones pictures
  • Isothiazolinones
    26172-55-4
  • US $1.00 / mg
  • 99
  • ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
  • Isothiazolinones pictures
  • Isothiazolinones
    26172-55-4
  • US $119.00-98.00 / kg
  • 99.9
  • Shandong Juchuang Chemical Co., LTD

26172-55-4(Isothiazolinones)Related Search:

Methanol Paraquat dichloride Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Methylparaben Kresoxim-methyl
Acetonitrile 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Basic Violet 1 Methyl acetate Methyl acrylate
Isovanillin 1-ADAMANTYL ISOCYANATE 2-Isocyanatoethyl Acrylate ISOCYANIC ACID m-Tolyl isocyanate
TERT-BUTYL ISOCYANIDE Isoquinoline-5-sulphonyl chloride hydrochloride Methyl

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5-CHLORO-2-METHYL-ISOTHIAZOLIN-3(2H)-ONE 5-CHLORO-2-METHYLISOTHIAZOLINONE 5-CHLORO-2-METHYL-2,3-DIHYDROISOTHIAZOL-3-ONE METHYL/CHLOROMETHYLISOTHIAZOLINONE 2-METHYL-5-CHLOROISOTHIAZOLIN-3-ONE 5-CHLORO-2-METHYLISOTHIAZOLIN-3-ONE KATHON886F KATHONFP CHLOROMETHYLISOTHIAZOLINE 4-Isothiazolin-3-one,5-chloro-2-methyl- 5-chloro-2-methyl-4-isothiazolin-3-on 5-Chloro-2-methyl-4-isothiazolinone 5-CHLORIDE-2-METHYL-4-ISOTHIAZOLINE-3-KETONE 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (CMI) 5-CHLORO-2-METHYL-3(2H)-ISOTHIAZOLONE MIXED WITH 2-METHYL-3(2H)ISOTHIAZOLONE Methychloroisothiazolinone/Methylisothiazolinone 5-Chloro-2-Methyl-3(2H)-IsothiazoneMixedWith2-Methyl-3(2H)-Isothiazolone 5-Chloro-2-Methyl-3(2H)-Isothiazone 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (CMIT) Chloromethylisothiazolone Danisol-K Methylchloroisothiazolone 5-Chloro-2-methyl-Isothiazolin-3-one/ 2-Methyl-Isothiazolin-3-one(CMIT/MIT) 5-CHLORO-2-METHYL-3(2H)-ISOTHIAZOLE METHYL(CHLORO)ISOTHIAZOLINONEMIXTURE KATHON886MW KATHONLX CHLORMETHYLISOTHIAZOLINONE CMIT (5 chloro 2 Methyl 2H isothiazol-3-one Isothiazolinones(CMI/MI) 3(2H)-Isothiazolone, 5-chloro-2-methyl- 3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazolone CMIT/MIT MIXTURE Isothiazolinones 2-METHYL-5-CHLORO-4-ISO-THIAZOLINE-3-ONE 5-Chloro-2-Methyl-4-isothiazolin-3-one, >14% in water. CMIT/MIT-14 ANTI-IDAS(N-TERMINAL) antibody produced in rabbit IDAS Multicilin Protein Idas 5-cloro-2-methyl-4-isothiazolin-3-one/2-methyl-2h-isothiazol-3-one 5-chloro-2-methyl-isothiazolylthione-3 kathoncg5243 methylchloroisothiazoline 5-Chloro-2-methyl-Isothiazolone 5-CHLORO-2-METHYL-4-ISOTHIAZOLINE-3-ONE 5-CHLORO-2-METHYL-4-ISOTHIOAZOLIN-3-ONE Kathon WT mci/mi 5-Chlor-2-methyl-4-isothiazolin-3-on Reaktionsgemisch, best. aus 5-Chlor-2-methyl-2H-isothiazol-3-on und 2-Methyl-2H-isothiazol-3-on (3:1) 5-chloro-2-methyl-3(2h)-isothiazolon mixt. with 2-methyl-3(2h)-isothiazolon 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE SOLUTION MTL MIXIN CMI/MIT mixed isothiazolinones 5-Chloro-2-methyl-4-isothiazolin-3-one solution 2-Methyl 4-isothiazolin-3-one, 5-Chloro-2-methyl-4-isothiazolin-3-one