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V-9-M cholecystokinin nonapeptide

V-9-M cholecystokinin nonapeptide structure

CAS No.: 99291-20-0

Chemical Name:: V-9-M cholecystokinin nonapeptide

Synonyms: Cholecystokinin Precursor (24-32) (rat) H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OH;Smeglutide;Semaglutide（Recombinant）;Cholecystokinin Precursor;V-9-M cholecystokinin nonapeptide;L-Valyl-L-prolyl-L-valyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-prolyl-L-methionine;L-Methionine,L-valyl-L-prolyl-L-valyl-L-a-glutamyl-L-alanyl-L-valyl-L-a-aspartyl-L-prolyl-;L-Methionine, L-valyl-L-prolyl-L-valyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-prolyl-;(4S)-4-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-3-carboxy-1-[(2S)-2-[[(1S)-1-carboxy-3-methylsulfanylpropyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

CBNumber:: CB41331642

Molecular Formula:: C42H69N9O14S

Molecular Weight:: 956.11

MDL Number:: MFCD00076493

MOL File:: 99291-20-0.mol

Last updated:2024-03-26 17:16:27

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V-9-M cholecystokinin nonapeptide Properties

Boiling point	1350.7±65.0 °C(Predicted)
Density	1.306±0.06 g/cm3(Predicted)
pka	3.51±0.10(Predicted)
InChIKey	AIKMAJWJXJPJNB-HNRKYVDVNA-N

V-9-M cholecystokinin nonapeptide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	FC110391	Cholecystokinin Precursor (24-32) (rat) H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OH	99291-20-0	2mg	$205	2021-12-16	Buy
Biosynth Carbosynth	FC110391	Cholecystokinin Precursor (24-32) (rat) H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OH	99291-20-0	10mg	$697	2021-12-16	Buy
Biosynth Carbosynth	FC110391	Cholecystokinin Precursor (24-32) (rat) H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OH	99291-20-0	25mg	$1515.25	2021-12-16	Buy

Product number	Packaging	Price	Buy
FC110391	2mg	$205	Buy
FC110391	10mg	$697	Buy
FC110391	25mg	$1515.25	Buy

V-9-M cholecystokinin nonapeptide Chemical Properties,Uses,Production

Description

V-9-M Cholecystokinin nonapeptide is a glucagon-like peptide receptor agonist, namely GLP-1 receptor agonist. Human GLP-1 is a peptide hormone secreted by intestinal L cells. Cholecystokinin Precursor (24-32), rat has apparent sedative actions and prevents experimental amnesisa in rats.

Uses

V-9-M cholecystokinin nonapeptide belongs to the glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) class of hypoglycemic drugs, which increase insulin secretion in a glucose-dependent manner and inhibit glucagon secretion , and can promote gastric emptying, centrally suppress appetite, reduce food intake, and then reduce glucose absorption to achieve the effect of lowering blood sugar.

Mechanism of action

V-9-M cholecystokinin nonapeptide's mechanism of action is to act on islet beta cells, promote the synthesis and secretion of insulin, stimulate the proliferation and differentiation of islet beta cells, inhibit the apoptosis of islet beta cells, increase the number of islet beta cells, and protect islet function. It can also act on islet alpha cells, inhibit the release of glucagon, and reduce the release of hepatic glucose.

Solubility in organics

V-9-M cholecystokinin nonapeptide is soluble in DMSO solution, the reference solubility range is shown below:

storage

Store at low temperatures to avoid moisture:
Powder: -20°C, 3 years.
Solvents: -80°C, 2 years.

References

1. Takashima A, Itoh S. Neuropharmacological properties of V-9-M, a putative neuropeptide derived from procholecystokinin, in the rat. Can J Physiol Pharmacol. 1989 Mar;67(3):223-7. DOI: 10.1016/0301-0082(90)90035-F
2. Cholecytokinin (CCK) gene-related peptides: distribution and characterization of immunoreactive pro-CCK and an amino-terminal pro-CCK fragment in rat brain. DOI: 10.1016/0006-8993(85)90813-3
3. Cao G, Beinfeld MC. Calcium-dependent pro-cholecystokinin V-9-M immunoreactive peptide release from rat brain slices and CCK-secreting rat medullary thyroid carcinoma cells in culture. Peptides. 1992 Nov-Dec;13(6):1087-90. DOI: 10.1016/0196-9781(92)90011-Q

V-9-M cholecystokinin nonapeptide Preparation Products And Raw materials

Raw materials

Preparation Products

V-9-M cholecystokinin nonapeptide Suppliers

Global( 91)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Maintain Biotech Co., Ltd.	+86-75589664337 +86-15112661142	cami@maintain-bio.com	China	66	58
Hantai Biomedical Group Co. LTD	+8618819265912	id002@cnhantide.com	China	37	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Dorne Chemical Technology co. LTD	+86-13583358881 +86-18560316533	Ethan@dornechem.com	China	294	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+86-19164747840 +86-13119157289	13119157289@163.com	China	2971	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	sales@anbuchem.com	China	3000	58
Wuhan Haorong Biotechnology Co.,ltd	+8618565342920	sales@chembj.net	China	270	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58

Supplier	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	58
Maintain Biotech Co., Ltd.	58
Hantai Biomedical Group Co. LTD	58
Hebei Mojin Biotechnology Co., Ltd	58
Dorne Chemical Technology co. LTD	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Anbu Chem Co.,Ltd	58
Wuhan Haorong Biotechnology Co.,ltd	58
Anhui Ruihan Technology Co., Ltd	58

View Lastest Price from V-9-M cholecystokinin nonapeptide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-01	V-9-M cholecystokinin nonapeptide 99291-20-0	US $1.00 / g	1g	99%	100kg	Dorne Chemical Technology co. LTD
2024-04-29	V-9-M cholecystokinin nonapeptide 99291-20-0	US $0.00-0.00 / kg	20kg	99%	200000	Wuhan Haorong Biotechnology Co.,Ltd
2024-04-12	V-9-M cholecystokinin nonapeptide 99291-20-0	US $0.00 / kg	1kg	0.99	10T	Shandong Hanjiang Chemical Co., Ltd

V-9-M cholecystokinin nonapeptide
99291-20-0
US $1.00 / g
99%
Dorne Chemical Technology co. LTD

V-9-M cholecystokinin nonapeptide
99291-20-0
US $0.00-0.00 / kg
99%
Wuhan Haorong Biotechnology Co.,Ltd

V-9-M cholecystokinin nonapeptide
99291-20-0
US $0.00 / kg
0.99
Shandong Hanjiang Chemical Co., Ltd

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Cholecystokinin

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V-9-M cholecystokinin nonapeptide (4S)-4-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-3-carboxy-1-[(2S)-2-[[(1S)-1-carboxy-3-methylsulfanylpropyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid L-Methionine, L-valyl-L-prolyl-L-valyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-prolyl- L-Valyl-L-prolyl-L-valyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-prolyl-L-methionine Cholecystokinin Precursor (24-32) (rat) H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OH Smeglutide Cholecystokinin Precursor L-Methionine,L-valyl-L-prolyl-L-valyl-L-a-glutamyl-L-alanyl-L-valyl-L-a-aspartyl-L-prolyl- Semaglutide（Recombinant） 99291-20-0 91043-68-2 C42H69N9O14S Peptide 99291-20-0 API