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2,5-Dihydroxy-1,4-dithiane

2,5-Dihydroxy-1,4-dithiane structure

CAS No.: 40018-26-6

Chemical Name:: 2,5-Dihydroxy-1,4-dithiane

Synonyms: 1,4-DITHIANE-2,5-DIOL;DITHIANE;p-Dithiane-2,5-diol;FEMA 3826;1,4-Dithiane-2,5-dio;1,4-dithane-2,5-diol;MERCATOACETALDEHYDE DIMER;NSC 106280;4-dithiane;5-Dihydroxy-1

CBNumber:: CB4141273

Molecular Formula:: C4H8O2S2

Molecular Weight:: 152.24

MDL Number:: MFCD00006659

MOL File:: 40018-26-6.mol

MSDS File:: SDS

Last updated:2024-04-19 20:05:26

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2,5-Dihydroxy-1,4-dithiane Properties

Melting point	130 °C (dec.) (lit.)
Boiling point	244.73°C (rough estimate)
Density	1.224 (estimate)
vapor pressure	0Pa at 25℃
FEMA	3826 \| 2,5-DIHYDROXY-1,4-DITHIANE
refractive index	1.5200 (estimate)
storage temp.	2-8°C
solubility	H₂O: 0.39% at 20 °C
form	Crystalline Powder
pka	12.04±0.40(Predicted)
color	White to yellow
PH	4.9 (3.9g/l, H2O)
Odor	at 0.10 % in propylene glycol. sulfury meaty toasted bread broth egg tomato
Odor Type	sulfurous
Water Solubility	3.9 g/L (20 ºC)
JECFA Number	550
BRN	104402
InChIKey	YUIOPHXTILULQC-UHFFFAOYSA-N
LogP	-0.276 at 22.8℃ and pH6.3
CAS DataBase Reference	40018-26-6(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)	2,5-DIHYDROXY-1,4-DITHIANE
FDA UNII	R4F79F1JB0

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08,GHS09

Signal word

Danger

Hazard statements

H301-H317-H330-H373-H410

Precautionary statements

P260-P273-P280-P302+P352-P304+P340+P310-P314

Hazard Codes

Xn,Xi

Risk Statements

22-41-43-52/53-36/37/38

Safety Statements

26-36/37/39-61-37/39-24-36

RIDADR

UN2811

WGK Germany

1-8-10-13

HazardClass

6.1

PackingGroup

III

HS Code

29349990

NFPA 704

	1
2		1

2,5-Dihydroxy-1,4-dithiane price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	183954	1,4-Dithiane-2,5-diol 97%	40018-26-6	50g	$52.5	2023-01-07	Buy
Sigma-Aldrich	183954	1,4-Dithiane-2,5-diol 97%	40018-26-6	250g	$115	2023-01-07	Buy
TCI Chemical	D1761	2,5-Dihydroxy-1,4-dithiane >96.0%(GC)	40018-26-6	25g	$27	2024-03-01	Buy
TCI Chemical	D1761	2,5-Dihydroxy-1,4-dithiane >96.0%(GC)	40018-26-6	500g	$320	2024-03-01	Buy
Alfa Aesar	A14620	2,5-Dihydroxy-1,4-dithiane, 96%	40018-26-6	50g	$27.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
183954	50g	$52.5	Buy
183954	250g	$115	Buy
D1761	25g	$27	Buy
D1761	500g	$320	Buy
A14620	50g	$27.65	Buy

2,5-Dihydroxy-1,4-dithiane Chemical Properties,Uses,Production

Chemical Properties

white to yellowish crystalline powder

Chemical Properties

2,5-Dihydroxy-1,4-dithiane has a sulfurous, meaty, toasted bread-like odor

Uses

1,4-Dithiane-2,5-diol is a hydroxylated dithiane derivative with phytogrowth-inhibitory and antibacterial activities.

Uses

1,4-Dithiane-2,5-diol was used in the synthesis of:

substituted tetrahydrothiophene derivatives
2-amino-3-(arylsulfonyl)thiophenes, potential antiviral and antitumor agents

Definition

ChEBI: 1,4-Dithiane-2,5-diol is a member of dithianes.

Aroma threshold values

Aroma characteristics at 0.1% EtoH: sulfurous, grilled meaty, pungent, brothy, eggy, heavy and rich, toasted bread, tomato

Taste threshold values

Taste characteristics at 0.25 to 10 ppm: metallic, meaty savory chicken and beef, sulfurous, egg-yolk-like

Synthesis Reference(s)

Synthetic Communications, 14, p. 483, 1984 DOI: 10.1080/00397918408059569

General Description

1,4-Dithiane-2,5-diol undergoes bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction with chalcones to afford trisubstituted tetrahydrothiophenes. It participates in diastereoselective [3+3] cycloaddition with azomethine imines catalyzed by 1,4-diazabicyclo[2.2.2]octane. It is a mercaptoacetaldehyde dimer and an efficient synthon for incorporating a thiol group to in situ generated nitroalkenes.

2,5-Dihydroxy-1,4-dithiane synthesis

Synthesis of 2,5-Dihydroxy-1,4-dithiane from Chloroacetaldehyde

2,5-Dihydroxy-1,4-dithiane Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 2-aminothiophene-3-carboxylate 3-METHOXYCARBONYL-3-SULFOLENE methyl 2-(2-methoxy-2-oxoethyl)thiophene-3-carboxylate 2-AMINO-3-CYANOTHIOPHENE (2-AMINOTHIOPHEN-3-YL)(THIOPHEN-2-YL)METHANONE

(2-Amino-thiophen-3-yl)-(4-fluoro-phenyl)-methanone

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2,5-Dihydroxy-1,4-dithiane Suppliers

Global( 484)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12457	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7613	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58

View Lastest Price from 2,5-Dihydroxy-1,4-dithiane manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-20	2,5-Dihydroxy-1,4-dithiane 40018-26-6	US $35.00-1.10 / kg	1kg	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-11-01	2,5-Dihydroxy-1,4-dithiane/1,4-DITHIANE-2,5-DIOL 40018-26-6	US $0.00 / kg	1kg	99.0%min	10000kg	Hangzhou ICH Biofarm Co., Ltd
2023-11-01	3-Amino-5-mercapto-1,2,4-triazole 40018-26-6	US $0.00 / kg	1kg	99.0%min	10000kg	Hangzhou ICH Biofarm Co., Ltd

2,5-Dihydroxy-1,4-dithiane
40018-26-6
US $35.00-1.10 / kg
99%
Henan Fengda Chemical Co., Ltd

2,5-Dihydroxy-1,4-dithiane/1,4-DITHIANE-2,5-DIOL
40018-26-6
US $0.00 / kg
99.0%min
Hangzhou ICH Biofarm Co., Ltd

3-Amino-5-mercapto-1,2,4-triazole
40018-26-6
US $0.00 / kg
99.0%min
Hangzhou ICH Biofarm Co., Ltd

2,5-Dihydroxy-1,4-dithiane Spectrum

2,5-Dihydroxy-1,4-dithiane(40018-26-6)MS 2,5-Dihydroxy-1,4-dithiane(40018-26-6)¹HNMR 2,5-Dihydroxy-1,4-dithiane(40018-26-6)IR1 2,5-Dihydroxy-1,4-dithiane(40018-26-6)Raman

40018-26-6(2,5-Dihydroxy-1,4-dithiane)Related Search:

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Selenium sulfide Butylated Hydroxytoluene 1,2-Ethanedithiol 1,4-Dithiane 4-Dithiane-2,5-diol,2,5-dimethyl-

Ethyl 2-hydroxyethyl sulfide 2-(3,4-Dimethoxyphenyl)-N-(3,4-dimethoxyphenethyl)-N-methyl-1,3-dithiane-2-propan-1-amine 1,1,3,3-tetraoxide trans-1,2-Dithiane-4,5-diol, Oxidized DTT,trans-1,2-dithiane-4,5-diol,trans-1,2-Dithiane-4,5-diol, Oxidized DTT,rel-(4R*,5R*)-1,2-Dithiane-4,5-diol

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2,5-DIHYDROXY-1,4-DITHIANE 4-DITHIANE-2,5-DIOL p-Dithiane-2,5-diol, 95% 250GR 1,4-Dithian-2,5-diol NSC 106280 1,4-Dithiane-2,5-diol Mercaptoacetaldehyde Dimer p-Dithiane-2,5-diol C4H8O2S2 Dihydroxy-1,4-dit 2,5-Dihydroxy-1,4-dithiane, 98%, Mixture of isoMers 1,4-DITHIANE-2,5-DIOL 2,5-DIHYDROXY-1,4-DITHIANE 4-DITHIANE-2,5-DIOL DITHIANE FEMA 3826 2,5-Dihydroxy-1,4-dithiane, Mixture of isoMers 2.5- twohydroxytwo -1.4-dithiane MERCAPTOACETALDEHYDE DIMER LABOTEST-BB LT00138118 2 5-DIHYDROXY-1 4-DITHIANE 97+% MIXTU& 2,5-DIHYDROXY-1,4-DITHIANE, WACKERQUALIT Y 2,5-Dihydroxy-1,4-dithiane, pract., 95+% 2,5-DIHYDROXY-1,4-DITHIANE, 90+% 2,5-dimethyl-1,4-dithiane tetrahydro-p-dithiin 2,5-Dihydroxy-1,4-dithiane, Mercaptoacetaldehyde dimer 1,4-Dithiane-2,5-diol, 2,5-Dihydroxy-1,4-dithiane, Mercaptoacetaldehyde dimer p-Dithiane-2,5-diol,95% 4-dithiane 5-Dihydroxy-1 2,5-Dihydroxy-1,4-Dithiance 2,5-Dihydroxy-1,4-dithiane, 97%, mixture of isomers (2S,5R)-1,4-dithiane-2,5-diol 2,5-Dihydroxy-1,4-dithiane> 2,5-Dihydroxy-1,4-dithiane[DHDT] 1, 4-dithio-2, 5-diol 2,5-Dihydroxy-1,4-dithiane, 97%+ p-Dithiane-2,5-diol, 96%, 1,4-DITHIANE-2,5-DIOL MERCATOACETALDEHYDE DIMER 1,4-Dithiane-2,5-dio DITHIANE FEMA 3826 p-Dithiane-2,5-diol 1,4-dithane-2,5-diol 2,5-Dihydroxy-1,4-Dithuane 1,4-Dithiane-2,5-diol (9CI, ACI) 2,5-Dihydroxy-1,4-dithiane/1,4-DITHIANE-2,5-DIOL 1,4-dithial-2,5-diol 40018-26-6 CH2SCH2CH2SCH2 C4H8O2S2 C4H8O2S2C4H8O2S2C4H8O2S2C4H8O2S2 Heterocyclic Building Blocks Others S-Containing Building Blocks Heterocyclic Compounds aldehyde Flavor Building Blocks Chemical Synthesis Heterocyclic Building Blocks Others