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Ephedrine sulfate

CAS No.
134-72-5
Chemical Name:
Ephedrine sulfate
Synonyms
Nci-c55;isofedrol;2:1)(salt);nci-c55652;EPHEDRINE SULFATE;l-ephedrinesulfate;1-Ephedrine sulfate;EPHEDRINESULFATE,USP;(-)-EPHEDRINE SULFATE;EPHEDRINE SULFATE 99%
CBNumber:
CB4208592
Molecular Formula:
C10H17NO5S
Molecular Weight:
263.31
MDL Number:
MFCD00066147
MOL File:
134-72-5.mol
Last updated:2023-05-25 18:01:08

Ephedrine sulfate Properties

Melting point 248 °C
alpha D25 -30 to -32.5° (c = 5)
Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
LogP 1.054 (est)
FDA 21 CFR 341.16; 341.20
CAS DataBase Reference 134-72-5(CAS DataBase Reference)
FDA UNII U6X61U5ZEG
EPA Substance Registry System Ephedrine sulfate (134-72-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS06
Signal word  Danger
Hazard statements  H301-H317
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-25
RIDADR  1544
HazardClass  6.1(b)
PackingGroup  III
HS Code  29394100

Ephedrine sulfate Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

Labeled analogue of (-)-erythro-Ephedrine Sulfate, the sulfate salt of the α- and β-adrenergic agonist Ephedrine. (-)-erythro-Ephedrine is a sympathomimetic amine with stimulant properties. (-)-erythr o-Ephedrine Sulfate is a bronchodilator used in the treatment of asthma.

Uses

(-)-erythro-Ephedrine Sulfate is the sulfate salt of the α- and β-adrenergic agonist Ephedrine. (-)-erythro-Ephedrine is a sympathomimetic amine with stimulant properties. (-)-erythro-Ephedrine Sulfate is a bronchodilator used in the treatment of asthma.

brand name

Isofedrol (Boehringer Mannheim GmbH, Germany).

General Description

White microcrystalline powder. Odorless. Central nervous system stimulant.

Air & Water Reactions

Water soluble.

Reactivity Profile

Aqueous solution are slightly acidic. Ephedrine sulfate is incompatible with strong oxidizers.

Fire Hazard

Flash point data for Ephedrine sulfate are not available; however, Ephedrine sulfate is probably combustible.

Safety Profile

Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by intravenous route: increased pulse rate and blood pressure. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also EPHEDRINE.

Ephedrine sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-ephedrinesulfate(2:1)(salt 1-alpha-(1-(methylamino)ethyl)benzylalcoholsulfate 1-phenyl-2-methylamine-propanol-1-sulfate 2:1)(salt) alpha-[1-(methylamino)ethyl]-benzenemethano[theta-(theta,s)]-benzenemethanosulfate( isofedrol 1-Ephedrine sulfate l-ephedrinesulfate nci-c55652 (1R,2S)-(-)-Ephedrine sulfate bis[[r-(r*,s*)]-beta-hydroxy-alpha-methylphenethyl methylammonium] sulphate (-)-EPHEDRINE SULFATE EPHEDRINE SULFATE Ephedrine sulfate USP24 EPHEDRINE SULFATE 99% 1-Phenyl-2-methylaminopropanol sulfate EPHEDRINESULFATE,USP (1R,2S)-(-)-Ephedrine sulfate,98.00% Nci-c55 Ephedrine Sulfate (200 mg) (List Chemical) (-)-erythro-Ephedrine Sulfate (αR)-,α-[(1S)-1-(MethylaMino)ethyl]benzeneMethanol HeMisulfate (-)-Ephedrine-d3 Sulfate (-)-erythro-1-Hydroxy-2-(MethylaMino)-1-phenylpropane-d3 Sulfate (-)-erythro-Ephedrine-d3 Sulfate (1R,2S)-(-)-Ephedrine-d3 Sulfate (1R,2S)-1-Phenyl-2-MethylaMinopropanol-1-d3 Sulfate (αR)-,α-[(1S)-1-(MethylaMino)ethyl]benzeneMethanol-d3 HeMisulfate l-Ephedrine-d3 Sulfate (-)-erythro-1-Hydroxy-2-(methylamino)-1-phenylpropane sulfate (1R,2S)-1-Phenyl-2-methylaminopropanol-1 sulfate Benzenemethanol, a-[1-(methylamino)ethyl]-, [R-(R*,S*)]-, sulfate (2:1) CAVQBDOACNULDN-KHFUBBAMSA-N 2-(Methylamino)-1-phenylpropan-1-ol sulfate Pseudoephedrine Hydrochloride EP Impurity A as Sulfate 134-72-5 2C10H15NOH2O4S C10H15NO05H2SO4 Amines Aromatics Intermediates & Fine Chemicals Neurochemicals Pharmaceuticals