ChemicalBook >> CAS DataBase List >>Aurora Kinase Inhibitor III
Aurora Kinase Inhibitor III
- CAS No.
- 879127-16-9
- Chemical Name:
- Aurora Kinase Inhibitor III
- Synonyms
- AKI-7169;Aurora Kinase Inhibitor 3;Aurora Kinase Inhibitor III;AKI-7169(Aurora Kinase Inhibitor III);Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem;N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide;N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-;Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide;Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
- CBNumber:
- CB42098016
- Molecular Formula:
- C21H18F3N5O
- Molecular Weight:
- 413.4
- MDL Number:
- MFCD09265250
- MOL File:
- 879127-16-9.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:13
| Density | 1.456±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: <2mg/mL |
| pka | 14.51±0.70(Predicted) |
| form | White solid |
| color | white |
| FDA UNII | E9Q3ZU9CRL |
Aurora Kinase Inhibitor III price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21851 | Aurora Kinase Inhibitor III ≥98% | 879127-16-9 | 500μg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 21851 | Aurora Kinase Inhibitor III ≥98% | 879127-16-9 | 1mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 21851 | Aurora Kinase Inhibitor III ≥98% | 879127-16-9 | 5mg | $570 | 2024-03-01 | Buy |
| Biorbyt Ltd | orb611996 | Aurora Kinase Inhibitor III >98% | 879127-16-9 | 250mg | $1654.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611996 | Aurora Kinase Inhibitor III >98% | 879127-16-9 | 1g | $3282.7 | 2021-12-16 | Buy |
Aurora Kinase Inhibitor III Chemical Properties,Uses,Production
General Description
A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC50 = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC50 = 131, 386, 591, and 887 nM, respectively).
Biochem/physiol Actions
Target IC50: 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively
Aurora Kinase Inhibitor III Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 46)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9747 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4153 | 55 | |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 991 | 55 |
Aurora Kinase Inhibitor III
Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide
N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
AKI-7169
Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem
Aurora Kinase Inhibitor 3
Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-
Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide >=98% (HPLC), solid
AKI-7169(Aurora Kinase Inhibitor III)
N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide
Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
879127-16-9