ChemicalBook >> CAS DataBase List >>DGAT-1 inhibitor
DGAT-1 inhibitor
- CAS No.
- 959122-11-3
- Chemical Name:
- DGAT-1 inhibitor
- Synonyms
- CS-121;A922500;DGAT-1 inhibitor;DGAT-1 Inhibitor 4a;DGAT-1 Inhibitor, A 922500;DGAT-1 inhibitor USP/EP/BP;A922500(DGAT-1 Inhibitor 4a);DGAT-1 Inhibitor A922500 A-922500;DGAT-1 INHIBITOR 4A; A-922500; A922500;Diacyl glycerolacyltransferase 1 inhibitor
- CBNumber:
- CB42470944
- Molecular Formula:
- C26H24N2O4
- Molecular Weight:
- 428.48
- MDL Number:
- MFCD12828780
- MOL File:
- 959122-11-3.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:01:58
| Density | 1.323 |
|---|---|
| storage temp. | -20°C |
| solubility | ≥21.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH |
| form | Light yellow solid |
| FDA UNII | 44698M475X |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06, GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H319-H410 | |||||||||
| Precautionary statements | P273-P301+P310-P305+P351+P338-P501 | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 25-36-50 | |||||||||
| Safety Statements | 26-45-61 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
DGAT-1 inhibitor price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A1737 | A922500 | 959122-11-3 | 1MG | $57.5 | 2023-06-20 | Buy |
| Sigma-Aldrich | A1737 | A922500 | 959122-11-3 | 5MG | $242 | 2023-06-20 | Buy |
| Sigma-Aldrich | A1737 | A922500 | 959122-11-3 | 10MG | $413 | 2023-06-20 | Buy |
| Sigma-Aldrich | 252801 | DGAT-1 Inhibitor, A 922500 | 959122-11-3 | 5mg | $298 | 2022-05-15 | Buy |
| Cayman Chemical | 10012708 | A-922500 ≥95% | 959122-11-3 | 1mg | $38 | 2024-03-01 | Buy |
DGAT-1 inhibitor Chemical Properties,Uses,Production
Uses
A922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages.
Definition
ChEBI: A 922500 is an aromatic ketone.
Biological Activity
Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC 50 values are 7 and 24 nM at human and mouse DGAT-1 respectively) that is devoid of activity at DGAT-2, ACAT1 or ACAT2. Induces significant weight loss without altering food intake, and decreases liver and plasma triglyceride levels in vivo . Orally active.
Biochem/physiol Actions
The diacylglycerol acyltransferase (DGAT) 1 inhibitor A922500 was shown to effectively reduce postprandial serum triglyceride levels in rodents at concentrations of 0.03, 0.3 and 3 mg/kg. These results suggest A922500 may have beneficial effects in reducing the risk of cardiovascular disease.
DGAT-1 inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 117)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Suzhou Victorypharm Co.,Ltd. | +86-13916956214 | sales@victory-pharm.com | China | 1301 | 58 |
View Lastest Price from DGAT-1 inhibitor manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![(1R,2R)-2-[[4'-[[(Phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/8bc99468-0952-462c-b2a2-9c76546d4ce8.jpg) |
2020-01-10 | (1R,2R)-2-[[4'-[[(Phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid
959122-11-3
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- (1R,2R)-2-[[4'-[[(Phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid
959122-11-3
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co
959122-11-3(DGAT-1 inhibitor)Related Search:
(1R,2R)-2-[[4'-[[(Phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid
DGAT-1 inhibitor
Diacyl glycerolacyltransferase 1 inhibitor
A922500
A922500(DGAT-1 Inhibitor 4a)
enylureido)biphenyl(1R,2R)-2-(4'-(3-phcarbonyl)cyclopentanecarboxylic acid
DGAT-1 Inhibitor 4a
(1R,2R)-2-(4'-(3-phenylureido)biphenylcarbonyl)cyclopentanecarboxylic acid
Cyclopentanecarboxylic acid, 2-[[4'-[[(phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]-, (1R,2R)-
(1R,2R)-2-(4,-(3-phenylureido)-[1,1,-biphenyl]-4-carbonyl)cyclopentanecarboxylic acid
DGAT-1 Inhibitor, A 922500
CS-121
DGAT-1 Inhibitor, A 922500 - CAS 959122-11-3 - Calbiochem
DGAT-1 INHIBITOR 4A; A-922500; A922500
DGAT-1 inhibitor USP/EP/BP
DGAT-1 Inhibitor A922500 A-922500
(1R,2R)-2-(4'-(3-Phenylureido)-[1,1'-biphenyl]-4-carbonyl)cyclopentanecarboxylic acid
959122-11-3
Inhibitor
Inhibitors
APIs