N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
- CAS No.
- 1246298-48-5
- Chemical Name:
- N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
- Synonyms
- 20:0(2S-OH) Ceramide;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE;Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
- CBNumber:
- CB42719825
- Molecular Formula:
- C38H75NO4
- Molecular Weight:
- 610.01
- MDL Number:
- MOL File:
- 1246298-48-5.mol
N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Chemical Properties,Uses,Production
General Description
Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin. 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration.
Biochem/physiol Actions
Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an?antitumor drug to exhibit its activity.
N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Preparation Products And Raw materials
Raw materials
Preparation Products
N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
| SHANGHAI ZZBIO CO., LTD. | 021-58979353 18019707223 | tech@zzbioco.com | China | 12065 | 58 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| Aladdin Scientific | 58 |
| Sigma-Aldrich | 80 |
| Codow Chemical Co.,Ltd. | 55 |
| Chengdu Dianchun Technology Co., Ltd | 60 |
| SHANGHAI ZZBIO CO., LTD. | 58 |