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Retinyl acetate

Retinyl acetate Structure
Retinyl acetate structure
CAS No.
127-47-9
Chemical Name:
Retinyl acetate
Synonyms
VITAMIN A ACETATE;RETINOL ACETATE;retinyl;VITAMIN A ACETAT;RETINOL ACETATE ALL TRANS;ALL-TRANS-RETINYL ACETATE;Myvak;Myvax;Crystalets;VitaMin A ace
CBNumber:
CB4308339
Molecular Formula:
C22H32O2
Molecular Weight:
328.49
MDL Number:
MFCD00019413
MOL File:
127-47-9.mol
MSDS File:
SDS
Last updated:2024-03-27 16:59:26
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Retinyl acetate Properties

Melting point 57-58 °C
Boiling point 406.22°C (rough estimate)
Density 1.0474 (rough estimate)
refractive index 1.547-1.555
Flash point 14℃
storage temp. 2-8°C
solubility absolute ethanol: 25 mg/mL
form solid or viscous liquid
color Yellow powder
Odor Amine like
Water Solubility soluble
Sensitive Light & Air Sensitive & Hygroscopic
Merck 14,10013
BRN 1915439
Stability Hygroscopic, Light Sensitive
InChIKey QGNJRVVDBSJHIZ-QHLGVNSISA-N
LogP 9.4 at 25℃
FDA 21 CFR 582.5933; 310.545
Substances Added to Food (formerly EAFUS) VITAMIN A ACETATE
SCOGS (Select Committee on GRAS Substances) Vitamin A acetate
CAS DataBase Reference 127-47-9(CAS DataBase Reference)
FDA UNII 3LE3D9D6OY
NCI Drug Dictionary retinyl acetate
NIST Chemistry Reference Retinol, acetate(127-47-9)
EPA Substance Registry System Retinol acetate (127-47-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H360-H413
Precautionary statements  P201-P280-P308+P313
Hazard Codes  Xn,Xi,T,F
Risk Statements  38-63-36/37/38-53-61-11
Safety Statements  36/37-45-37/39-26-53-16
RIDADR  UN1170 - class 3 - PG 2 - Ethanol
WGK Germany  2
RTECS  VH6825000
F  1-8-10
TSCA  Yes
HS Code  29362100
Toxicity LD50 (10 day) orally in mice: 4100 mg/kg (Kamm)
NFPA 704
1
1 1

Retinyl acetate price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V-040 Retinyl acetate solution 100?μg/mL in ethanol (with 0.1% (w/v) BHT; degassed), reference material, Cerilliant? 127-47-9 1mL $106 2024-03-01 Buy
Sigma-Aldrich 46958 Retinyl acetate analytical standard 127-47-9 100mg $143 2024-03-01 Buy
Sigma-Aldrich 1716002 Retinyl acetate United States Pharmacopeia (USP) Reference Standard 127-47-9 10x0.5g $410 2022-05-15 Buy
Alfa Aesar A16237 Vitamin A acetate in gelatin, 500,000 I.U./g 127-47-9 25g $35.2 2021-12-16 Buy
Alfa Aesar A16237 Vitamin A acetate in gelatin, 500,000 I.U./g 127-47-9 100g $90 2021-12-16 Buy
Product number Packaging Price Buy
V-040 1mL $106 Buy
46958 100mg $143 Buy
1716002 10x0.5g $410 Buy
A16237 25g $35.2 Buy
A16237 100g $90 Buy

Retinyl acetate Chemical Properties,Uses,Production

Description

Retinyl acetate (retinol acetate, vitamin A acetate,127-47-9) is a natural form of vitamin A. It is the acetate ester of retinol. It consists of yellow crystals which are greasy or sticky. It has a mild, characteristic odor. It has potential antineoplastic and chemo-preventive activities. It can be used to fortify food with vitamin A. As vitamin A acetate can induce cell differentiation and inhibit cell proliferation, it is used in skin-conditioning agent.

Reference

Volker Bühler, Vademecum for Vitamin Formulations, 2001, ISBN 3-8047-1834-5

Chemical Properties

Crystalline

Uses

Retinyl acetate has been used:

  • a control diet to study its effect at different developmental periods in fish larvae
  • to study its inhibitory effects on Mycobacterium avium?subspecies?paratuberculosis?(MAP) strains
  • as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk

Uses

vitamin precursor

Uses

Essential micronutrient

Definition

ChEBI: Retinyl acetate is an acetate ester. It is functionally related to an all-trans-retinol.

General Description

Retinyl acetate is suitable for use in the retention identification of the analyte when using HPLC and GC. Not intended for use as an activity reference standard. It has been thoroughly evaluated to ensure the utmost quality. Neat, unless otherwise noted. Certificate of Composition provided with the purchase.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications. It acts as a chemopreventive agent. Retinyl acetate also has antineoplastic property.

Safety Profile

Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also VITAMIN A.

Purification Methods

The acetate is separated from retinol by column chromatography, then crystallised from MeOH. [Kofler and Rubin Vitamins and Hormones (NY) 18 315 1960 for purification methods]. Store it in the dark, under N2 or Ar, at 0o. [Beilstein 6 IV 4135.]

Retinyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

9-CIS-RETINAL β-Carotene

Retinyl acetate Suppliers

Global( 582)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Across Biotech Jinan Co LTD 		+8613031735486 frank@acrossbiotech.com China 105 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7534 58
Hebei Saisier Technology Co., LTD 		+86-18400010335 +86-13102810335 admin@hbsaisier.cn China 565 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+86-13474506593 +86-13474506593 sarah@tnjone.com China 848 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9350 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
Hubei XinRunde Chemical Co., Ltd. 		+8615102730682 bruce@xrdchem.cn CHINA 566 55
Supplier Advantage
Henan Bao Enluo International TradeCo.，LTD 		58
Across Biotech Jinan Co LTD 		58
Henan Fengda Chemical Co., Ltd 		58
Hebei Saisier Technology Co., LTD 		58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Hubei XinRunde Chemical Co., Ltd. 		55

Related articles

View Lastest Price from Retinyl acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ALL-TRANS-RETINYL ACETATE pictures 2024-04-12 ALL-TRANS-RETINYL ACETATE
127-47-9
 US $6.00 / KG 25KG MORE THAN 99% 20000KG/MONTH Hebei Saisier Technology Co., LTD
Retinyl acetate pictures 2024-03-27 Retinyl acetate
127-47-9
 US $5.00-0.10 / KG 1KG 98% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Vitamin A acetate pictures 2024-03-25 Vitamin A acetate
127-47-9
 US $0.00 / kg 1kg 99% 1000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
  • Retinyl acetate pictures
  • Retinyl acetate
    127-47-9
  • US $5.00-0.10 / KG
  • 98%
  • Henan Fengda Chemical Co., Ltd

Retinyl acetate Spectrum

Retinyl acetate(127-47-9)IR1

127-47-9(Retinyl acetate)Related Search:

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Methyl acetate INDOPHENOL ACETATE STARCH ACETATE Ethylene glycol diacetate Tocopherol
Isopropyl acetate Sodium acetate Vitamin A

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RETINYL ACETATE RETINOL ACETATE, WATER SOLUBLE VITAMIN A ACETATE, ALL TRANS VITAMIN A ACETATE 1500 TRANS-RETINOL ACETATE TRANS-RETINYL ACETATE VITAMIN-A-ACETATE STAB. BHA/BHT CONC. RETINOL ACETATE, 100MG, NEAT VITAMIN A (ACETATE) MEETS USP TESTING S RETINOL ACETATE ALL TRANS INSECT CELL*CU LTURE TESTE VITAMIN-A-ACETATE, STAB. DL-A-TOCOPHEROL ,CONC.(I.PEANUTOIL) RETINOL ACETATE ALL TRANS CELL*CULTURE T ESTED VitaminAAcetateForBiochemistry VitaminAAcetateB.P.,U.S.P. Vitamin A acetate in gelatin, powder all-trans-Retinyl acetate, 1.5 million IU/g, in sunflower oil, USP/EP, stab. Retinyl acetate solution Retinyl Acetate (Vitamin A Acetate) (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-4,6,8-nonatetraen- 1-ol Acetate all-trans-Retinol Acetat VitaMin A ace Retinyl (Retinol) Acetate VITAMINAACETATE(1,000,0001U/G) VITAMINAACETATE(1,500,0001U/G) VITAMINAACETATE(1,700,0001U/G) VITAMINAACETATE(2,000,0001U/G) VITAMINAACETATE(2,500,0001U/G) VITAMINAACETATE(2,800,0001U/G) VITAMINAACETATE,FEED,POWDER(1,000,0001U/G) VITAMINAACETATE,FEED,POWDER(1,500,0001U/G) VITAMINAACETATE,FEED,POWDER(500,0001U/G) VITAMINAACETATE,FEED,POWDER(650,0001U/G) VITAMINAACETATE,FOOD,POWDER(500,0001U/G) VITAMINAACETATE,SYNTHETIC,CRYSTALLINE VITAMINAACETATE,USP VITAMIN A ACETATE(RETINOL ACETATE)(RG) VITAMIN A ACETATE(RETINOL ACETATE)(AS) Antixerophthalmic vitamin acetate (2E,4E,6E,8E) -3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl) nona-2,4,6,8-tetraen-1-yl acetate Retinol acetate Vitamin A acetate all-trans Vitamin A acetate all-trans-Retinyl acetate Vitamin A Acetate, all trans(Synthetic) 500,000 USP u/g ALL-TRANS VITAMIN A ACETATE 3,7-Dimethyl-9-(2,6,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol acetate All-trans-retinol acetate Crystalets Davitan A 650 Myvak Myvax trans-Vitamin A acetate trans-vitaminaacetate Vitamin A alcohol acetate Vitamin A1 acetate vitaminaalcoholacetate VitamineAacetate VITAMIN A ACETATE(RETINYL ACETATE)(SH) Retinylacetat