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NIGERICIN SODIUM SALT

CAS No.
28380-24-7
Chemical Name:
NIGERICIN SODIUM SALT
Synonyms
x-464;Helix c;HELIXIN C;NIGERICIN;Aids003767;Aids-003767;AZALOMYCIN M;NIGERICIN NA;POLYETHERIN A;Antibiotic M 2
CBNumber:
CB4331016
Molecular Formula:
C40H68O11
Molecular Weight:
724.96
MDL Number:
MFCD00036825
MOL File:
28380-24-7.mol
Last updated:2023-05-18 11:31:15

NIGERICIN SODIUM SALT Properties

Melting point 183.5-185°
alpha D24 +36.2° (c = 0.842 in CHCl3)
Boiling point 779.9±60.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility chloroform: 10 mg/mL, clear, colorless
pka 4.39±0.10(Predicted)
EWG's Food Scores 1
FDA UNII RRU6GY95IS

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H319-H335-H301-H315
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  T,Xi
Risk Statements  25-36/37/38
Safety Statements  26-36/37/39-45-36
RIDADR  UN 3462 6.1/PG 3
WGK Germany  3
RTECS  QT6840000
10
HazardClass  6.1(b)
PackingGroup  III
HS Code  29419090
Toxicity LD50 in mice (mg/kg): 10-15 i.p. (Shoji); also reported as 2.5 i.p. (Harned)

NIGERICIN SODIUM SALT price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0003572 NIGERICIN 95.00% 28380-24-7 5MG $673.61 2021-12-16 Buy
American Custom Chemicals Corporation API0003572 NIGERICIN 95.00% 28380-24-7 10MG $686.65 2021-12-16 Buy
American Custom Chemicals Corporation API0003572 NIGERICIN 95.00% 28380-24-7 25MG $737.58 2021-12-16 Buy
AvaChem 2066 Nigericin 28380-24-7 1g $3250 2021-12-16 Buy
AvaChem 2066 Nigericin 28380-24-7 5mg $45 2021-12-16 Buy
Product number Packaging Price Buy
API0003572 5MG $673.61 Buy
API0003572 10MG $686.65 Buy
API0003572 25MG $737.58 Buy
2066 1g $3250 Buy
2066 5mg $45 Buy

NIGERICIN SODIUM SALT Chemical Properties,Uses,Production

Uses

Nigericin is a polyether antibiotic produced by Streptomyces, notably S. hygroscopicus, isolated in the 1950s. Its complex structure was finally elucidated in 1968. Nigericin is an ionophore, possessing very high affinity for monovalent cations such as Na+ and K+. Nigericin disrupts membrane potential and Golgi apparatus in mitochondria. Although nigericin can be isolated as the free acid (under acidic conditions), like most ionophores it is extracted into organic solvents and is most conveniently isolated as a salt. In vitro, nigericin has broad biological activity against Gram positive bacteria, fungi, tumour cell lines and some viruses, including HIV. Nigericin is the most common member of the polyether class which are common false positives in in vitro screening bioassays using crude microbial extracts. They are thus important standards for dereplication.

Definition

ChEBI: A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus.

NIGERICIN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

NIGERICIN SODIUM SALT Suppliers

Global( 117)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Shenzhen Excellent Biotech Co., Ltd.
13480692018 ramyan@ex-biotech.com CHINA 954 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10297 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5739 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17368 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Zhejiang Huida Biotech Co., LTD
008613515763466 8615669048680 wendy@huidabiotech.com CHINA 87 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9427 58
Hebei Duling International Trade Co. LTD
+8618032673083 sales05@hbduling.cn China 15755 58

View Lastest Price from NIGERICIN SODIUM SALT manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NIGERICIN SODIUM SALT pictures 2022-10-19 NIGERICIN SODIUM SALT
28380-24-7
US $50.00 / kg 1kg 99% 1 Hebei Duling International Trade Co. LTD
NIGERICIN SODIUM SALT pictures 2020-01-13 NIGERICIN SODIUM SALT
28380-24-7
US $1.00 / KG 1KG 98%-99.9% 200kg Career Henan Chemical Co
(2R)-2-((3S)-6-{[2-((5S)-5-{(3S)-5-[(3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethylperhydro-2H-pyran-2-yl]-3-methyloxolan-2-yl}-5-methyloxolan-2-yl)(2S,4R,9R,10R)-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methylperhydro-2H-pyran-2-yl)propanoic acid 28643-80-3 (Sodium salt) Aids003767 Aids-003767 Helix c AZALOMYCIN M HELIXIN C ANTIBIOTIC K178 ANTIBIOTIC K178 SODIUM SALT ANTIBIOTIC X-464 Polyetherin A, AzaloMycin M, Helixin C, K 178, X 464 Antibiotic M 2 x-464 NIGERICIN NIGERICIN NA NIGERICIN, NA SALT NIGERICIN, SODIUM SALT, STREPTOMYCES HYGROSCOPICUS POLYETHERIN A Nigericin from Streptomyces hygroscopicus Antibiotic K178 sodium salt, Azalomycin M nigericin sodium nigericin sodium from streptomyces*hygroscopicus nigericin sodium salt from streptomyces hygroscopicus NIGERICIN APPOX. 95% 28380-24-7 C40H68O11 BioChemical Antibiotics A to Z Antibiotics N-S Antibiotics antibiotic