Cynaroside
- CAS No.
- 5373-11-5
- Chemical Name:
- Cynaroside
- Synonyms
- LUTEOLIN-7-O-GLUCOSIDE;luteoloside;PETUNIDIN;LUTEOLIN-7-GLUCOSIDE;Galuteolin;cinaroside;glucoluteolin;Luteolin 7-O-β-D-glucopyranoside;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-;CYNAROSIDE
- CBNumber:
- CB4369516
- Molecular Formula:
- C21H20O11
- Molecular Weight:
- 448.38
- MDL Number:
- MFCD06799436
- MOL File:
- 5373-11-5.mol
Melting point | 256~258℃ |
---|---|
storage temp. | Sealed in dry,2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
Boiling point | 838.1±65.0 °C(Predicted) |
Density | 1.713±0.06 g/cm3(Predicted) |
pka | 6.10±0.40(Predicted) |
form | Solid |
color | Yellow to Very Dark Yellow |
Stability | Hygroscopic |
InChIKey | PEFNSGRTCBGNAN-QNDFHXLGSA-N |
SMILES | C1(C2=CC=C(O)C(O)=C2)OC2=C(C(O)=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=C2)C(=O)C=1 |&1:17,18,20,22,24,r| |
LogP | -0.090 (est) |
CAS DataBase Reference | 5373-11-5(CAS DataBase Reference) |
FDA UNII | 98J6XDS46I |
Cynaroside price More Price(44)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 1370837 | Luteolin 7-O-Glucoside United States Pharmacopeia (USP) Reference Standard | 5373-11-5 | 30mg | $692 | 2024-03-01 | Buy |
Sigma-Aldrich | 03600585 | Luteolin 7-glucoside primary pharmaceutical reference standard | 5373-11-5 | 10mg | $475 | 2024-03-01 | Buy |
Cayman Chemical | 25141 | Luteoloside ≥98% | 5373-11-5 | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 25141 | Luteoloside ≥98% | 5373-11-5 | 10mg | $130 | 2024-03-01 | Buy |
Sigma-Aldrich | 74284 | Luteolin 7-O-β-D-glucoside ≥98.0% (HPLC) | 5373-11-5 | 10mg | $536 | 2024-03-01 | Buy |
Cynaroside Chemical Properties,Uses,Production
Effects
Luteolin has a strong bactericidal effect on the respiratory tract, and it is the main active ingredient in the treatment of bronchitis in Qinglan, a unique medicinal material in Xinjiang. Lowers the role of cholesterol in atherosclerosis and enhances capillary relaxation.
Description
Luteolin-7-O-glucoside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. Luteoloside blocks 3C protease activity (IC50 = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM). It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg. Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod .
Chemical Properties
Off-white powder
Uses
Luteolin 7-Glucoside is a strong antioxidant ant radical scavenger. Used in cancer prevention.
Definition
ChEBI: A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Cynaroside Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Cynaroside manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-20 | Cynaroside
5373-11-5
|
US $0.00 / g | 10g | 98% | 2 | Changsha Staherb Natural Ingredients Co., Ltd. | ||
2024-08-15 | Cynaroside
5373-11-5
|
US $30.00-10.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | ||
2023-09-06 | Cynaroside
5373-11-5
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
- Cynaroside
5373-11-5
- US $0.00 / g
- 98%
- Changsha Staherb Natural Ingredients Co., Ltd.
- Cynaroside
5373-11-5
- US $30.00-10.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
- Cynaroside
5373-11-5
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.