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2,4-Dihydroxyacetophenone

2,4-Dihydroxyacetophenone structure

CAS No.: 89-84-9

Chemical Name:: 2,4-Dihydroxyacetophenone

Synonyms: 1-(2,4-dihydroxyphenyl)ethanone;Ethanone, 1-(2,4-dihydroxyphenyl)-;RESACETOPHENONE;2,4-DHAP;HyMechroMone;NSC 37559;NSC 10883;AKOS 90593;Resoacetophenone;4-Acetoresorcinol

CBNumber:: CB4391766

Molecular Formula:: C8H8O3

Molecular Weight:: 152.15

MDL Number:: MFCD00002279

MOL File:: 89-84-9.mol

MSDS File:: SDS

Last updated:2024-04-22 18:05:02

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2,4-Dihydroxyacetophenone Properties

Melting point	143-144.5 °C(lit.)
Boiling point	234.6°C (rough estimate)
Density	1.18 g/mL at 25 °C(lit.)
refractive index	1.4945 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	7.96±0.18(Predicted)
form	Crystalline Powder or Crystals
color	Off-white to pink to brown
PH	5 (1g/l, H2O, 20℃)
Sensitive	Moisture Sensitive
Merck	14,8140
BRN	1282505
InChIKey	SULYEHHGGXARJS-UHFFFAOYSA-N
LogP	1.480 (est)
CAS DataBase Reference	89-84-9(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	UC3V356VZC
NIST Chemistry Reference	Ethanone, 1-(2,4-dihydroxyphenyl)-(89-84-9)
EPA Substance Registry System	Ethanone, 1-(2,4-dihydroxyphenyl)- (89-84-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P264-P280-P305+P351+P338-P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25

WGK Germany

RTECS

AM7525000

Hazard Note

Irritant

TSCA

Yes

HS Code

29145000

NFPA 704

	0
1		0

2,4-Dihydroxyacetophenone price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D107409	2′,4′-Dihydroxyacetophenone 99%	89-84-9	100g	$93.9	2024-03-01	Buy
Sigma-Aldrich	D107409	2′,4′-Dihydroxyacetophenone 99%	89-84-9	500g	$110.4	2024-03-01	Buy
TCI Chemical	D0561	2',4'-Dihydroxyacetophenone >98.0%(GC)(T)	89-84-9	25g	$47	2024-03-01	Buy
TCI Chemical	D0561	2',4'-Dihydroxyacetophenone >98.0%(GC)(T)	89-84-9	100g	$120	2024-03-01	Buy
Alfa Aesar	A12066	2',4'-Dihydroxyacetophenone, 98%	89-84-9	50g	$37.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
D107409	100g	$93.9	Buy
D107409	500g	$110.4	Buy
D0561	25g	$47	Buy
D0561	100g	$120	Buy
A12066	50g	$37.65	Buy

2,4-Dihydroxyacetophenone Chemical Properties,Uses,Production

Chemical Properties

2,4-Dihydroxyacetophenone appears as a yellow-brown to reddish-brown fine crystalline powder. It slowly decomposes in water and can dissolve in hot alcohol, pyridine, and glacial acetic acid. In contrast, it is nearly insoluble in ether, benzene, and chloroform. A reaction with iron chloride causes it to adopt a red hue.

Uses

2,4-Dihydroxyacetophenone (cas# 89-84-9) is a compound useful in organic synthesis. It is also used as intermediate for pharmaceuticals. Reagent for iron as a 10% alcoholic solution. A red color is obtained with ferric ions in slightly acid solution: Cooper, Ind. Eng. Chem. Anal. Ed. 9, 334 (1937).

Preparation

Preparation by reaction of acetic acid on resorcinol,
with zinc chloride (Nencki reaction) (94%)
with boron trifluoride
with Amberlite IR-120 (a cation exchange resin, sulfonic acid type) (87%)
with polyphosphoric acid (63%)
with 70% perchloric acid (33%).

Definition

ChEBI: 2',4'-dihydroxyacetophenone is a dihydroxyacetophenone that is acetophenone carrying hydroxy substituents at positions 2' and 4'. It has a role as a plant metabolite. It is a member of resorcinols and a dihydroxyacetophenone.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 428, 1948 DOI: 10.1021/ja01181a521

Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. A severe eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

2,4-Dihydroxyacetophenone is obtained by the acetylation of resorcinol and acetic acid. In addition, it can also be obtained by reacting resorcinol with chloroacetyl or acetic anhydride in the presence of zinc chloride.

target

Phospholipase (e.g. PLA)

2,4-Dihydroxyacetophenone Preparation Products And Raw materials

Raw materials

Zinc chloride Benzene

Preparation Products

7-Hydroxycoumarin 1-[4-(Benzoyloxy)-2-hydroxyphenyl]-3-phenyl-1,3-propanedione 1-(2,4-Bis(benzoyloxy)phenyl)ethanone 7-HYDROXYFLAVONE 2',4'-DIHYDROXYCHALCONE

3,7-DIHYDROXYFLAVONE 4-HYDROXY-7-METHOXYCOUMARIN 7-HYDROXYFLAVANONE ROBINETIN 4'-Benzyloxy-2'-hydroxyacetophenone

4-Ethylresorcinol 4-[3-(2,4-Dimethoxy-3-methylphenyl)propyl]-1,3-benzenediol 2,4-Dimethoxyacetophenone

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2,4-Dihydroxyacetophenone Suppliers

Global( 638)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Hebei Guanlang Biotechnology Co,.LTD	+8619930503252	daisy@crovellbio.com	China	5964	58
Firsky International Trade (Wuhan) Co., Ltd	+8615387054039	admin@firsky-cn.com	China	436	58
Anhui Yiao New Material Technology Co., Ltd	+86-199-55145978 +8619955145978	sales8@anhuiyiao.com	China	253	58
Xiamen Work-For-World Medicine Co.,Ltd.	+undefined15921822462	keqingyong@wfwmed.com	China	193	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	1696	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Guanlang Biotechnology Co,.LTD	58
Firsky International Trade (Wuhan) Co., Ltd	58
Anhui Yiao New Material Technology Co., Ltd	58
Xiamen Work-For-World Medicine Co.,Ltd.	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55

View Lastest Price from 2,4-Dihydroxyacetophenone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-22	4-Acetylresorcinol 89-84-9	US $10.00 / kg	1kg	99.6%	100000	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-03-27	2,4-Dihydroxyacetophenone 89-84-9	US $1.00-1.00 / kg	1kg	99%HPLC	kg	Xiamen Work-For-World Medicine Co.,Ltd.
2023-11-06	2,4-Dihydroxyacetophenone 89-84-9	US $20.00-1.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.

4-Acetylresorcinol
89-84-9
US $10.00 / kg
99.6%
Ouhuang Engineering Materials (Hubei) Co., Ltd

2,4-Dihydroxyacetophenone
89-84-9
US $1.00-1.00 / kg
99%HPLC
Xiamen Work-For-World Medicine Co.,Ltd.

2,4-Dihydroxyacetophenone
89-84-9
US $20.00-1.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

2,4-Dihydroxyacetophenone Spectrum

2,4-Dihydroxyacetophenone(89-84-9)MS 2,4-Dihydroxyacetophenone(89-84-9)¹HNMR 2,4-Dihydroxyacetophenone(89-84-9)IR1 2,4-Dihydroxyacetophenone(89-84-9)Raman

89-84-9(2,4-Dihydroxyacetophenone)Related Search:

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3-Nitroacetophenone Acetophenone 2',4'-dihydroxybutyrophenone 2-Methylresorcinol 3-Hydroxyphenyl acetate

3',5'-DIHYDROXYACETOPHENONE,3,5-DIHYDROXYACETOPHENONE,3,5-DIHYDROXYACETOPHENONE MONOHYDRATE,3',5'-Dihydroxyacetophenone 3,5-Dihydroxyacetophenone PURPUROGALLIN 2,4,4'-TRIHYDROXYBENZOPHENONE

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Resoacetophenone Resorcinol, 4-acetyl- 2,4-Dihydroxyacetoph NSC 10883 NSC 37559 4-Acetylresorcinol Resacetophenone IMp. A (EP): 1,3-Dihydroxybenzene (Resorcinol) IMp. B (EP): 7-Hydroxy-2-Methyl-4H-1-benzopyran-4-one 2,4- twohydroxyAcetophenone 2',4'-Dihydroxyacetophenone, 97+% 2,4-Dihydroxy acetophenone (2-acetyl resorcinol) 2"4"-DIHYDROXYACETOPHENONERESACETOPHENONE 2',4'-Dihydroxyacetophenone 4-Acetylresorcinol 2,4-Dihydroxyacetophenone 2,4-Dihydroxyacetophenone,99% 2,4-DIHYDROXYACETOPHENONE extrapure 1-Acetyl-2,4-dihydroxybenzene, 4-Acetylresorcinol, Resacetophenone 2,4-Dihydroxylacetophenone 2-Acetyl-1,5-benzenediol 4-Acetoresorcinol 2',4'-Dihydroxyacetophenone,98% 2',4'-Dihydroxyacetophenone≥ 99% (HPLC) 2,4-DIHYDROXY ACETPHENONE 2',4'-DIHYDROXYACETOPHENONE 2,4-DIHYDROXYACETOPHENONE 1-ACETYL-2,4-DIHYDROXYBENZENE AKOS BBS-00004294 AKOS 90593 1-(2,4-dihydroxyphenyl)-ethanon 1-(2,4-Dihydroxyphenyl)-ethanone 1-Acetylbenzene-2,4-diol 2’,4’-dihydroxy-acetophenon 4-Acetyl-1,3-benzenediol 4-acetyl-resorcino Acetophenone, 2',4'-dihydroxy- beta-Resacetophenone b-Resacetophenone 4-ACETYLRESORCINOL 2,4-Dihydroxyacetophenone C8H8O3 2',4'-Dihydroxyacetophenone > High quality 2,4-Dihydroxyacetophenone Resorcinol Impurity 3 2,4-Dihydroxy-Acetophenone (Resacetophenone -99%) 89-84-9 2,4-Dihydroxyacetophenone 2,4-DIHYDROXY ACETOPHENONE For Synthesis HyMechroMone Ethanone, 1-(2,4-dihydroxyphenyl)- 1-(2,4-dihydroxyphenyl)ethanone RESACETOPHENONE 2,4-DHAP +C1Resacetophenone 2',4'-Dihydroxyacetophenone 89-84-9 98-84-9 CH3COC6H3OH2 KETONE Building Blocks C7 to C8 Carbonyl Compounds