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Buprofezin

CAS No.
69327-76-0
Chemical Name:
Buprofezin
Synonyms
BUTYL;BUPROFENZIN;Buprofezine;PP618;Aproad;Appland;NNI 750;VIAPPLA;APPLAUD;BUPROLEX
CBNumber:
CB4436924
Molecular Formula:
C16H23N3OS
Molecular Weight:
305.44
MDL Number:
MFCD01681899
MOL File:
69327-76-0.mol
Last updated:2024-03-25 20:41:16

Buprofezin Properties

Melting point 104-106°C
alpha 22 º (c=8,6N HCl)
Boiling point 273°C (12 torr)
Density 1.18
vapor pressure 1.25 x l0-3 Pa (25 °C)
refractive index 1.52-1.522
Flash point 176-178°C
storage temp. 0-6°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 3.02±0.20(Predicted)
color White to Pale Beige
Water Solubility 0.9 mg/L at 20 ºC
Decomposition 176-178 ºC
BRN 8324923
CAS DataBase Reference 69327-76-0(CAS DataBase Reference)
FDA 21 CFR 175.300
EWG's Food Scores 1
FDA UNII 3B8KGI239I
NIST Chemistry Reference 4H-1,3,5-thiadiazin-4-one, 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-(69327-76-0)
EPA Substance Registry System Buprofezin (69327-76-0)
Pesticides Freedom of Information Act (FOIA) Buprofezin

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS09
Signal word  Warning
Hazard statements  H373-H410
Precautionary statements  P260-P273-P314-P391-P501
RIDADR  UN3077(solid)
WGK Germany  2
RTECS  XI2865000
Toxicity LD50 in mice, rats (mg/kg): 10000, 8740 orally; LC50 (48 hr) in carp: 2-10 mg/l (Kanno, 1981)

Buprofezin price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 37886 Buprofezin PESTANAL?, analytical standard 69327-76-0 100mg $108 2024-03-01 Buy
Cayman Chemical 24137 Buprofezin ≥95% 69327-76-0 50mg $33 2024-03-01 Buy
Cayman Chemical 24137 Buprofezin ≥95% 69327-76-0 100mg $62 2024-03-01 Buy
TRC B689670 Buprofezin 69327-76-0 250mg $145 2021-12-16 Buy
American Custom Chemicals Corporation API0001787 BUPROFEZIN 95.00% 69327-76-0 5MG $550 2021-12-16 Buy
Product number Packaging Price Buy
37886 100mg $108 Buy
24137 50mg $33 Buy
24137 100mg $62 Buy
B689670 250mg $145 Buy
API0001787 5MG $550 Buy

Buprofezin Chemical Properties,Uses,Production

Uses

Buprofezin is a contact and ingested insecticide, active against Homoptera (whiteflies, leafhoppers, scale insects, etc.) in and on citrus, cotton, cucumbers, tomatoes, sweet potatoes, rice, etc.

Uses

Insecticide.

Uses

Buprofezin is a insecticide which works as a chitin synthesis inhibitor. Buprofezin is used to control stubborn rice pests and is effective in controlling green leaf hoppers and white back plant hoppe rs for long durations.

Definition

ChEBI: Buprofezin is a 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one in which the C=N double bond has Z configuration. It has a role as an insecticide and a member of homopteran inhibitor of chitin biosynthesis.

Hazard

Moderately toxic by ingestion. Low toxic- ity by skin contact.

Agricultural Uses

Insecticide, Acaricide, Insect growth regulator: For insect control in food crops and greenhouse ornamentals.

Trade name

APPLAUD®; NNI-750®

Pharmacology

The foregoing indicates that the modes of action of buprofezin and benzoylureas could be similar or identical. However, one differing biochemical effect of buprofezin is inhibition of prostaglandin biosynthesis (33), a mechanism that has been suggested as responsible for its ovicidal activity. Subsequently, the in vitro and in vivo effects of buprofezin were found to be strongly antagonized by 20- hydroxyecdysone (34), which also affected prostaglandin biosynthesis. Thus, inhibition of both prostaglandin and chitin biosynthesis by buprofezin was prevented by 20- hydroxyecdysone, so that both effects of the insecticide are mediated via an effect on the hormone concentration or its receptor. Consequently, buprofezin seems to inhibit the drop in the 20-hydroxyecdysone titer that triggers epidermal cell proliferation, old cuticle digestion, and new cuticle deposition, but the detailed mechanism of this action has yet to be established.

Metabolic pathway

Buprofezin gradually decomposes in soils under flooded and upland conditions, with half-lives of 104 and 80 days, respectively. After 150 days, five degradation products are identified as 2-tert- butylimino-5-(4-hydroxyphenyl)-3-isopropylperhydro- 1,3,5-thiadiazin-4-one, 3-isopropyl-5-phenylperhydro- 1,3,5-thiadiazin-2,4-dione, 1-tert-butyl-3-ispropyl-5- phenylbiuret, 1-isopropyl-3-phenylurea, and phenylurea. As minor products, 2-tert-butylimino-5- phenylperhydro-1,3,5-thiadiazin-4-one or buprofezin sulfoxide are found in the flooded or in the upland soils. Since neither formation of 14CO2 nor hydroxylation is observed in the sterile soils, buprofezin seems to have undergone complete mineralization in soils under both conditions through biological transformation by soil microorganisms.

Degradation

Buprofezin (1) was degraded under acidic conditions with half-lives (DT50) f 6-12 days (pH 4), 34 days (pH 6) and 65 days (pH 10) at 40 °C. Opening of the thiadiazinanone ring appeared to be the primary hydrolytic degradation pathway, to yield 1-tert-butyl-3-isopropyl-5-phenyl-2- thiobiuret (2) and N-isopropyl-N-phenylurea (3) as major products.
Buprofezin is stable to aqueous photolysis. The estimated DT50 of buprofezin in distilled water when exposed to UV light was 39 days. A more complex photodegradation pathway of buprofezin in methanol was reported recently (Datta and Walia, 1997) with DT9 values of 4 hours and 15 days under UV and sunlight irradiation, respectively.

Global( 247)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5988 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 2263 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58

View Lastest Price from Buprofezin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Buprofezin pictures 2024-03-25 Buprofezin
69327-76-0
US $50.00 / kg 1kg 99% 30 tons Hebei Yanxi Chemical Co., Ltd.
Buprofezin pictures 2023-01-31 Buprofezin
69327-76-0
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Buprofezin pictures 2021-08-10 Buprofezin
69327-76-0
US $40.00 / KG 1KG 99 10 tons Shijiazhuang tongyang Import and Export Co., LTD
  • Buprofezin pictures
  • Buprofezin
    69327-76-0
  • US $50.00 / kg
  • 99%
  • Hebei Yanxi Chemical Co., Ltd.
  • Buprofezin pictures
  • Buprofezin
    69327-76-0
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • Buprofezin pictures
  • Buprofezin
    69327-76-0
  • US $40.00 / KG
  • 99
  • Shijiazhuang tongyang Import and Export Co., LTD
3,5-Thiadiazin-4-one,2-[(1,1-dimethylethyl)imino]tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1 4H-1,3,5-Thiadiazin-4-one, 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl- 4h-1,3,5-thiadiazin-4-one,2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylet Appland Aproad buprofenzin,w.p. NNI 750 2-tert-Butylimino-3-isopropyl-5-phenyl-3,4,5,6-tetrahydro-2H-1,3,5-thiodiazin-4-one 2-tert-Butylimino-3-isopropyl-5-phenylperhydro-1,3,5-thiadiazinan-4-one (2Z)-2-([(Z)-1,1-Dimethylethyl]imino)-3-isopropyl-5-phenyl-1,3,5-thiadiazinan-4-one 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-4h-1,3,5-t 2-tert-Butylimino-3-isopropyl-5-phenyl-1,3,5-thiadiazinan-4-one 2-tert-Butylimino-3-isopropyl-5-phenyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazin-4-one Burprofezin hiadiazin-4-one 2-tert-buthylimino-3-iso-propyl-5-phenyl-3,4,5,6-tetraphydro-2H-1,3,5-thiadiaziana-4-one 2-tert-Butylimino-3-isopropyl-5-phenyl-2,3,5,6-tetrahydro-4H-1,3,5-thiadiazin-4-one 2-tert-Butyliminotetrahydro-3-isopropyl-5-phenyl-4H-1,3,5-thiadiazin-4-one 2-T-BUTYLIMINO-3-ISOPROPYL-5-PHENYLPERHYDRO-1,3,5-THIADIAZINAM-4-ONE 2-((1,1-Dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1,3,5-thiadiazin-4-one 2-(tert-Butylimino)-3-isopropyl-5-phenylperhydro-1,3,5-thidiazin-4-one Buprofezin 100mg [69327-76-0] BUPROFEZINSTANDARD (Z)-2-(tert-butylimino)-5-(4-hydroxyphenyl)-3-isopropyl-1,3,5-thiadiazinan-4-one (Z)-buprofezin VIAPPLA hyl)-5-phenyl- PP618 BUPROFEZIN BUPROLEX APPLAUD APPLAUD(R) 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-4h-1,3,5-thiadiazin-4-one 2-(tert-Butylimino)-3-isopropyl-5-phenylperhydro-1,3,5-thidiazin-4-one 2-TERT-BUTYLAMINO-3-ISOPROPYL-5-PHENYL-1,3,5-THIADIAZINAN-4-ONE MARATHON BUPROFEZIN PESTANAL BUPROFEZIN, 100MG, NEAT 2-tert-Butylimino-3-isopropyl-5-phenylperhydro-1,3,5-thiadiazin-4-one 2-tert.-Butylimino-3-isopropyl-5-phenylperhydro-1,3,5-thiodiazin-4-one buprofezin (bsi,iso) 2-tert-butylimino-5-(4-hydroxyphenyl)-3-propan-2-yl-1,3,5-thiadiazinan-4-one Buprofezin@1000 μg/mL in Acetone Buprofezin @100 μg/mL in Methanol BuprofezinSolution,1,000mg/L,1ml Buprofezin Reference Material BuprofezinSolution,100mg/L,1ml Buprofezin 25%SC Insecticides for Rice potatoes citrus CAS No 69327-76-0 (EZ)-Buprofezin Buprofezine BUTYL BUPROFENZIN Mitotane-13C 69327-76-0 9327-76-0 C16H23N3OS Pesticides&Metabolites INSECTICIDE BI - BZPesticides