4-Acetoxyindole
- CAS No.
- 5585-96-6
- Chemical Name:
- 4-Acetoxyindole
- Synonyms
- 1H-indol-4-yl acetate;2-(1H-indol-4-yl)acetate;Acetic acid 1H-indol-4-yl ester;ACETOXYINDOLE;4-ACETOXYINDOLE;4-acacetoxyindole;4-INDOLYL ACETATE;4-INDOXYL ACETATE;4-Acetoxy-1H-indole;4-Acetoxyindole 98%
- CBNumber:
- CB4477655
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD00010678
- MOL File:
- 5585-96-6.mol
- MSDS File:
- SDS
| Melting point | 100-102°C |
|---|---|
| Boiling point | 339.1±15.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 16.38±0.30(Predicted) |
| color | Off-White to Beige |
| InChI | InChI=1S/C10H9NO2/c1-7(12)13-10-4-2-3-9-8(10)5-6-11-9/h2-6,11H,1H3 |
| InChIKey | ZXDMUHFTJWEDEF-UHFFFAOYSA-N |
| SMILES | N1C2=C(C(OC(=O)C)=CC=C2)C=C1 |
| CAS DataBase Reference | 5585-96-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Hazard Codes | Xi |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 2933998090 |
4-Acetoxyindole price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 259047 | 4-Indolyl acetate 99% | 5585-96-6 | 250mg | $51.24 | 2024-03-01 | Buy |
| TRC | A165853 | 4-Acetoxyindole | 5585-96-6 | 100mg | $60 | 2021-12-16 | Buy |
| TRC | A165853 | 4-Acetoxyindole | 5585-96-6 | 500mg | $75 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H23-1-0H | 4-Acetoxyindole 98% | 5585-96-6 | 5G | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA03468 | 4-Acetoxyindole | 5585-96-6 | 2g | $100 | 2021-12-16 | Buy |
4-Acetoxyindole Chemical Properties,Uses,Production
Description
4-acetoxylindole is also known as 4-Indolyl acetate. It can be used as standards of the reverse phase HPLC during separation of small molecules. It can also be used as reactant during the preparation of inhibitors of HIV-attachment, prostanoid EP3 antagonist, indolyl-nitroalkanes and psilocybin.
Uses
Reactant for preparation of:• ;Inhibitors of HIV-1 attachment1• ;Prostanoid EP3 receptor antagonist, as a novel antiplatelet agent2• ;Indolyl-nitroalkanes via N-bromosuccinimide catalyzed synthesis3• ;Psilocybin as a medicinal agent4
Uses
4-Acetoxyindole is a useful intermediate for organic synthesis of Psilocine and Psilocine analogs.
Uses
Reactant for preparation of:
- Inhibitors of HIV-1 attachment
- Prostanoid EP3 receptor antagonist, as a novel antiplatelet agent
- Indolyl-nitroalkanes via N-bromosuccinimide catalyzed synthesis
- Psilocybin as a medicinal agent
General Description
4-Acetoxyindole is a chromophore that belongs to the pyrrole family of compounds. It has been shown to react with an ionic liquid under acidic conditions to form a protonated intermediate, which can be deprotonated by a nucleophile. This reaction yields an acetate anion and a fluorescing product. 4-Acetoxyindole also reacts with deuterium gas, yielding an acetate, a deuterium atom, and fluorescing product. The reaction is reversible and the yield of the product depends on the concentration of the reactants. 4-Acetoxyindole has strong carbonyl groups that make it reactive towards other functional groups. These reactions are useful for synthesizing heterocycles such as indoles and isoquinolines.
References
http://www.sigmaaldrich.com/catalog/product/aldrich/259047?lang=en®ion=US
https://pubchem.ncbi.nlm.nih.gov/compound/4-Acetoxyindole
4-Acetoxyindole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12477 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Suzhou Chukai Pharma Tech Co.,Ltd | +8615062531973 | 2279973922@qq.com | China | 224 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12457 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Guangzhou Tengyue Chemical Co., Ltd. | +86-86-18148706580 +8618826483838 | evan@tyvovo.com | China | 152 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7613 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
View Lastest Price from 4-Acetoxyindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-15 | 4-Acetoxyindole
5585-96-6
|
US $1.00 / mg | 10mg | 99 | 5ton/month | ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | |
 |
2024-03-29 | 4-Acetoxyindole
5585-96-6
|
US $35.00-1.20 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-12-26 | 4-Acetoxyindole
5585-96-6
|
US $90.00 / kg | 1kg | 99% Purity (What/sapp: +86 18145728414) | 1000 Tons/Month | Guangzhou Tengyue Chemical Co., Ltd. |
-
- 4-Acetoxyindole
5585-96-6
- US $1.00 / mg
- 99
- ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
-
- 4-Acetoxyindole
5585-96-6
- US $35.00-1.20 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-Acetoxyindole
5585-96-6
- US $90.00 / kg
- 99% Purity (What/sapp: +86 18145728414)
- Guangzhou Tengyue Chemical Co., Ltd.