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1-Methylpiperazine

1-Methylpiperazine Structure
1-Methylpiperazine structure
CAS No.
109-01-3
Chemical Name:
1-Methylpiperazine
Synonyms
N-METHYLPIPERAZINE;methylpiperazine;NMPRZ;4-Methylpiperazine;N-Methylpiperazin;Piperazine,1-methyl-;CL046;AKOS BBS-00003665;1-methyl-piperazin;1-METHYLPIPERAZINE
CBNumber:
CB4478526
Molecular Formula:
C5H12N2
Molecular Weight:
100.16
MDL Number:
MFCD00005966
MOL File:
109-01-3.mol
MSDS File:
SDS
Last updated:2024-01-22 16:43:48
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1-Methylpiperazine Properties

Melting point -6 °C
Boiling point 138 °C(lit.)
Density 0.903 g/mL at 25 °C(lit.)
vapor density 3.5 (vs air)
vapor pressure 12 hPa (20 °C)
refractive index n20/D 1.466(lit.)
Flash point 108 °F
storage temp. 2-8°C
solubility Chloroform (Soluble), Methanol (Soluble)
pka pK1:4.94(+2);pK2:9.09(+1) (25°C,μ=0.1)
form Liquid
color Clear
Specific Gravity 0.903
PH 11-12 (50g/l, H2O, 20℃)
explosive limit 1.2-9.9%(V)
Viscosity 2.27mm2/s
Water Solubility soluble
Sensitive Hygroscopic
BRN 102724
InChIKey PVOAHINGSUIXLS-UHFFFAOYSA-N
LogP -0.57 at 25℃
CAS DataBase Reference 109-01-3(CAS DataBase Reference)
FDA UNII B92I95EL9Q
NIST Chemistry Reference Piperazine, 1-methyl-(109-01-3)
EPA Substance Registry System Piperazine, 1-methyl- (109-01-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H226-H312-H314-H331
Precautionary statements  P210-P260-P280-P304+P340+P310-P305+P351+P338-P370+P378
Hazard Codes  T,F,C,Xi
Risk Statements  10-21-23-34-36/37/38-20/21
Safety Statements  16-26-36/37/39-45-36
RIDADR  UN 2734 8/PG 2
WGK Germany  2
RTECS  TM1225000
Autoignition Temperature 320 °C
Hazard Note  Flammable/Toxic/Corrosive/Store under nitrogen
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29335995
Toxicity LD50 orally in Rabbit: 2547 mg/kg LD50 dermal Rabbit 1341 mg/kg
NFPA 704
2
2 0

1-Methylpiperazine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.05859 1-Methylpiperazine for synthesis 109-01-3 5ml $35 2024-03-01 Buy
Sigma-Aldrich BP1118 1-Methylpiperazine British Pharmacopoeia (BP) Reference Standard 109-01-3 15MG $229 2024-03-01 Buy
Sigma-Aldrich 8.05859 1-Methylpiperazine for synthesis 109-01-3 250ML $120 2024-03-01 Buy
Sigma-Aldrich 130001 1-Methylpiperazine 99% 109-01-3 5g $36.5 2024-03-01 Buy
Sigma-Aldrich 14549 1-Methylpiperazine analytical standard 109-01-3 5ml $70.8 2024-03-01 Buy
Product number Packaging Price Buy
8.05859 5ml $35 Buy
BP1118 15MG $229 Buy
8.05859 250ML $120 Buy
130001 5g $36.5 Buy
14549 5ml $70.8 Buy

1-Methylpiperazine Chemical Properties,Uses,Production

Chemical Properties

clear liquid

Uses

1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

Uses

1-Methylpiperazine is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP)

Definition

ChEBI: 1-Methylpiperazine is a N-methylpiperazine.

Hazard

Moderate fire risk.

Flammability and Explosibility

Flammable

Safety Profile

Poison by intraperitoneal route. Moderately toxic by inhalation, ingestion, and skin contact. A severe skin and eye irritant. Flammable liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx.

1-Methylpiperazine synthesis

16339-07-4
109-01-3
6928-85-4
Synthesis of 1-Methylpiperazine from 1-methyl-4-nitrosopiperazine

1-Methylpiperazine Preparation Products And Raw materials

Raw materials

PIPERAZINE DIHYDROCHLORIDE PIPERAZINE HEXAHYDRATE Carbon dioxide Piperazine Methanol

Preparation Products

AZIMILIDE 3-(4-Methylpiperazin-1-yl)aniline 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbaldehyde 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbonitrile 1-Amino-4-methylpiperazine
Zopiclone 1-METHYLPIPERAZINE DIHYDROCHLORIDE 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonyl chloride 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide (2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanamine
3-(4-Methylpiperazin-1-ylmethyl)benzoic acid 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxylic acid 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonitrile CHLORCYCLIZINE HYDROCHLORIDE Levofloxacin
(3,4-DIAMINO-PHENYL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxamide (2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanol Ethyl 2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxylate 3-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZALDEHYDE
(4-METHYL-PIPERAZIN-1-YL)-ACETIC ACID Ethyl 2-(4-methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate 3-Hydrazinyl-1-(4-methylpiperazin-1-yl)propan-1-one CHLORCYCLIZINE 2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine
1-AdaMantanethylaMine 1-FORMYL-4-METHYLPIPERAZINE 4-(4-METHYLPIPERAZINOMETHYL)BENZOIC ACID (2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanol 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbaldehyde
Clozapine 1-METHYL-4-(3-NITROPHENYL)PIPERAZINE 4-[(4-Methylpiperazin-1-yl)methyl]aniline 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylic acid 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-amine
4-(4-Methylpiperazino)aniline 1-METHYL-4-(4-NITROPHENYL)PIPERAZINE 2-Hydrazinyl-1-(4-methylpiperazin-1-yl)ethanone 1-METHYL-4-(4-NITROBENZYL)PIPERAZINE 1-methyl-4-nitrosopiperazine

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1-Methylpiperazine Suppliers

Global( 755)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Believe Chemical PTE.LTD
+86-18553607090 +8618553607090 1093908296@qq.com China 1684 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Sinoway Industrial co., ltd. 		0592-5800732; +8613806035118 xie@china-sinoway.com China 992 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7377 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Speranza Chemical Co., Ltd. 		+86-86-075521030354 +8618688942810 sophieliu@speranzachem.com China 723 55
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
Supplier Advantage
Shandong Believe Chemical PTE.LTD
58
Hebei Yanxi Chemical Co., Ltd. 		58
Sinoway Industrial co., ltd. 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Speranza Chemical Co., Ltd. 		55
Hefei TNJ Chemical Industry Co.,Ltd. 		55

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View Lastest Price from 1-Methylpiperazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Methylpiperazine pictures 2024-04-19 1-Methylpiperazine
109-01-3
 US $5.00 / kg 1kg ≥98% 500mt/year Jinan Finer Chemical Co., Ltd
1-Methylpiperazine pictures 2024-04-10 1-Methylpiperazine
109-01-3
 US $0.00 / Kg/Bag 2Kg/Bag 99% up, High Density 20 tons Sinoway Industrial co., ltd.
1-Methylpiperazin pictures 2024-01-22 1-Methylpiperazin
109-01-3
 US $8.00-0.80 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • 1-Methylpiperazine pictures
  • 1-Methylpiperazine
    109-01-3
  • US $0.00 / Kg/Bag
  • 99% up, High Density
  • Sinoway Industrial co., ltd.

1-Methylpiperazine Spectrum

1-Methylpiperazine(109-01-3)MS1-Methylpiperazine(109-01-3)1HNMR1-Methylpiperazine(109-01-3)13CNMR1-Methylpiperazine(109-01-3)IR11-Methylpiperazine(109-01-3)IR21-Methylpiperazine(109-01-3)Raman

109-01-3(1-Methylpiperazine)Related Search:

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1-methyl-piperazin 1-METHYLPIPERAZINE FOR SYNTHESIS Cyclizine Related CoMpound A N-Methyl piperazine 1-Methylpiperazine, 99+% 100GR 1-Methylpiperazine, 99+% 500GR 1-Methylpiperazine, 99+% 5GR LABOTEST-BB LTBB000517 METHYLPIPERAZINE-N 1-METHYLPIPERAZINE AKOS BBS-00003665 1-METHYLPIPERAZINE, STANDARD FOR GC N-MethylPiperazineForSynthesis N-EthylPiperazineForSynthesis N-Methylpiperazine, 98+% 1-Methylpiperazine, 99+% n-METHYL PIPERAZINE extrapure 1-Methylpiperazine, 98+% Olanzapine Impurity 15 CL046 1-Methylpiperazine / N-Methylpiperazine 1-Methylpiperazine> Cyclizine impurity A CRS Diethylcarbamazine EP Impurity A Imatinib EP Impurity G N-Methylpiperazini N-METHYL PIPERASINE 1-Methylpiperazine ISO 9001：2015 REACH 1-Methylpiperazine extrapure, 99% Cyclizine impurity A (Y0000886) Cyclizine Related Compound A (1-methylpiperazine) (1154015) N-METHYLPIPERAZINE NMPRZ 4-Methylpiperazine methylpiperazine N-Methylpiperazin Piperazine,1-methyl- Cyclizine USP Related Compound A Imatinib Mesilate EP Impurity G Imatinib Impurity 54 Cyclizine Hydrochloride Impurity A Imatinib Mesilate Impurity G 109-01-3 1109-01-3 203-639-5 468-79-0 NC4H8NCH3 AMINE Building Blocks Analytical Standards Analytical Chromatography Product Catalog Alphabetic Piperazines META - METH Heterocyclic Building Blocks Benzotriazoles ,Triazoles Building Blocks C4 to C8