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6-Chloronicotinic acid

CAS No.
5326-23-8
Chemical Name:
6-Chloronicotinic acid
Synonyms
2-chloro-5-pyrdinecarboxylic acid;2-chloropyridine-5-carboxylic acid;6-CHLOROPYRIDINE-3-CARBOXYLIC ACID;6-ChL;6-Chloronicoti;TIMTEC-BB SBB004004;RARECHEM AL BO 0729;6 - chlorine niacin;6-Chloronicotinic ac;2-Chloroncotinic acid
CBNumber:
CB4707499
Molecular Formula:
C6H4ClNO2
Molecular Weight:
157.55
MDL Number:
MFCD00006241
MOL File:
5326-23-8.mol
MSDS File:
SDS
Last updated:2024-01-22 16:43:48

6-Chloronicotinic acid Properties

Melting point 190 °C (dec.)(lit.)
Boiling point 241.15°C (rough estimate)
Density 0.5
refractive index 1.5870 (estimate)
Flash point 192°C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility deionized water: soluble
form Crystalline Powder
pka 3.24±0.10(Predicted)
color Off-white to beige
Water Solubility Soluble in water (2 mg/ml at 20°C), ethanol, methanol, DMSO, and slightly soluble in chloroform.
Decomposition 192 ºC
BRN 115993
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey UAWMVMPAYRWUFX-UHFFFAOYSA-N
CAS DataBase Reference 5326-23-8(CAS DataBase Reference)
FDA UNII 99V0U0120A
NIST Chemistry Reference 6-Chloronicotinic acid(5326-23-8)
EPA Substance Registry System 6-Chloronicotinic acid (5326-23-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25-37/39
WGK Germany  3
TSCA  T
HazardClass  IRRITANT
HS Code  29333999
NFPA 704
0
2 0

6-Chloronicotinic acid price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 156353 6-Chloropyridine-3-carboxylic acid 99% 5326-23-8 5g $45.7 2024-03-01 Buy
Sigma-Aldrich 156353 6-Chloropyridine-3-carboxylic acid 99% 5326-23-8 25g $57.4 2024-03-01 Buy
TCI Chemical C1116 6-Chloronicotinic Acid >98.0%(T) 5326-23-8 25g $92 2024-03-01 Buy
TCI Chemical C1116 6-Chloronicotinic Acid >98.0%(T) 5326-23-8 100g $274 2024-03-01 Buy
Alfa Aesar A15620 6-Chloronicotinic acid, 99% 5326-23-8 5g $35.65 2024-03-01 Buy
Product number Packaging Price Buy
156353 5g $45.7 Buy
156353 25g $57.4 Buy
C1116 25g $92 Buy
C1116 100g $274 Buy
A15620 5g $35.65 Buy

6-Chloronicotinic acid Chemical Properties,Uses,Production

Chemical Properties

Off-white to beige crystalline powder

Uses

6-Chloropyridine-3-carboxylic acid (6-chloronicotinic acid/6-CNA) has been used to study its photolytic and photocatalytic degradation. 6-CNA is a degradation product of neonicotinoid insecticides imidacloprid and acetamiprid and is known to appear in different environmental matrices. The product has been used as a media component during the isolation of 6-CNA degrading bacterial strain from imidacloprid-exposed soil samples.

Uses

6-Chloronicotinic acid is used as building block for different chemical synthesis. It is an intermediate for the synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAFV600E inhibitors, and novel DNA-gyrase B inhibitors.

Definition

ChEBI: 6-Chloronicotinic acid is a member of pyridines and an aromatic carboxylic acid.

General Description

6-Chloropyridine-3-carboxylic acid is a metabolite of the neonicotinoid pesticides, imidacloprid and acetamiprid and occurs in different environmental matrices.(3) It is widely used in agricultural crop protection, domestic insect control and environmental pest management.

Purification Methods

Purify it by recrystallisation from hot H2O and sublime it in a vacuum. [Pechmann & Welsch Chem Ber 17 2384 1884, Herz & Murty J Org Chem 26 122 1961, Beilstein 22/2 V 177.]

5006-66-6
5326-23-8
Synthesis of 6-Chloronicotinic acid from 2-Hydroxy-5-pyridinecarboxylic acid
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View Lastest Price from 6-Chloronicotinic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Chloronicotinic acid pictures 2024-01-22 6-Chloronicotinic acid
5326-23-8
US $8.00-0.80 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
6-Chloronicotinic acid pictures 2023-08-23 6-Chloronicotinic acid
5326-23-8
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
6-Chloronicotinic Acid pictures 2023-03-06 6-Chloronicotinic Acid
5326-23-8
US $10.70 / Kg/Bag 10g 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
6-Chloronicotinic acid, 6-Chloropyridine-3-carboxylic acid 3-Carboxy-6-chloropyridine 6-Chloronicotinic acid ,97% 6-Chloropyridine-3-carboxylic acid,6-Chloronicotinic acid 6-Chloronicotinic ac RARECHEM AL BO 0729 TIMTEC-BB SBB004004 3-Pyridinecarboxylic acid, 6-chloro- 6-chloro-3-pyridinecarboxylicaci 6-CHLORONICOTINIC ACID 6-CHLORO-3-PYRIDINECARBOXYLIC ACID 6-Chloronicotinic acid, 99% 25GR 6-Chloronicotinic acid, 99% 5GR 2-chloro-5-pyridincarboxylic acid 2-chloro-5-pyridineforMic acid 6-chloro-3-pyridincarboxylic acid 6-chloro-3-pyridineforMic acid 6-Chloropyridine-3-carboxylic acid, 5-Carboxy-2-chloropyridine 6-Chloronicotiinic acid 6-Chloro nicotintic acid 6-Chloropyridine-3-carboxylic acid 99% 6 - chlorine niacin 6-Chloronicoti 2-Chloroncotinic acid 6-Chloronicotinicacid,99% 6-chloro-3-carboxylic acid 6-Cholre Nicotinic Acid 6-Chloronicotinic acid 98% 6-CHLORO-3-PYRIDINECARBOXYLIC ACID / 6-CHLORONICOTINIC ACID 6-CHLORO NICOTINIC ACID 6-CHLORO NICOTINIC ACID 6-Chloronicotinic acid Solution 6-Chloropyridine-3-carboxylic acid@100 μg/mL in Methanol [carbonyl-14C1]-6-chloronicotinic acid 6-Chloronicotinic Acid Standard 6-Chloropyridine-3-carboxylic acid@1000 μg/mL in Acetonitrile 6-Chloronicotinic Acid > 6-Chloronicotinic acid (6-CNA) 6-Chloronicotinic acid USP/EP/BP Imidacloprid Impurity 14 TIANFUCHEM--5326-23-8--High purity 6-Chloronicotinic acid factory price 6-Chloronicotinic acid,100ppm 6-ChL 2-chloro-5-pyrdinecarboxylic acid 2-chloropyridine-5-carboxylic acid 6-CHLOROPYRIDINE-3-CARBOXYLIC ACID 2-Chloro pyidine-5-carboxylic acid 5326-23-8 5236-23-8 Building Blocks Halopyridines Chloropyridines Halogenated Heterocycles Heterocyclic Building Blocks Pyridines pyridine series Picolinic acid series Carboxylic Acids Organic acids