6-Chloronicotinic acid
- CAS No.
- 5326-23-8
- Chemical Name:
- 6-Chloronicotinic acid
- Synonyms
- 2-chloro-5-pyrdinecarboxylic acid;2-chloropyridine-5-carboxylic acid;6-CHLOROPYRIDINE-3-CARBOXYLIC ACID;6-ChL;6-Chloronicoti;TIMTEC-BB SBB004004;RARECHEM AL BO 0729;6 - chlorine niacin;6-Chloronicotinic ac;2-Chloroncotinic acid
- CBNumber:
- CB4707499
- Molecular Formula:
- C6H4ClNO2
- Molecular Weight:
- 157.55
- MDL Number:
- MFCD00006241
- MOL File:
- 5326-23-8.mol
- MSDS File:
- SDS
Melting point | 190 °C (dec.)(lit.) |
---|---|
Boiling point | 241.15°C (rough estimate) |
Density | 0.5 |
refractive index | 1.5870 (estimate) |
Flash point | 192°C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | deionized water: soluble |
form | Crystalline Powder |
pka | 3.24±0.10(Predicted) |
color | Off-white to beige |
Water Solubility | Soluble in water (2 mg/ml at 20°C), ethanol, methanol, DMSO, and slightly soluble in chloroform. |
Decomposition | 192 ºC |
BRN | 115993 |
Stability | Stable. Incompatible with strong oxidizing agents. |
InChIKey | UAWMVMPAYRWUFX-UHFFFAOYSA-N |
CAS DataBase Reference | 5326-23-8(CAS DataBase Reference) |
FDA UNII | 99V0U0120A |
NIST Chemistry Reference | 6-Chloronicotinic acid(5326-23-8) |
EPA Substance Registry System | 6-Chloronicotinic acid (5326-23-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-24/25-37/39 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | T | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29333999 | |||||||||
NFPA 704 |
|
6-Chloronicotinic acid price More Price(47)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 156353 | 6-Chloropyridine-3-carboxylic acid 99% | 5326-23-8 | 5g | $45.7 | 2024-03-01 | Buy |
Sigma-Aldrich | 156353 | 6-Chloropyridine-3-carboxylic acid 99% | 5326-23-8 | 25g | $57.4 | 2024-03-01 | Buy |
TCI Chemical | C1116 | 6-Chloronicotinic Acid >98.0%(T) | 5326-23-8 | 25g | $92 | 2024-03-01 | Buy |
TCI Chemical | C1116 | 6-Chloronicotinic Acid >98.0%(T) | 5326-23-8 | 100g | $274 | 2024-03-01 | Buy |
Alfa Aesar | A15620 | 6-Chloronicotinic acid, 99% | 5326-23-8 | 5g | $35.65 | 2024-03-01 | Buy |
6-Chloronicotinic acid Chemical Properties,Uses,Production
Chemical Properties
Off-white to beige crystalline powder
Uses
6-Chloropyridine-3-carboxylic acid (6-chloronicotinic acid/6-CNA) has been used to study its photolytic and photocatalytic degradation. 6-CNA is a degradation product of neonicotinoid insecticides imidacloprid and acetamiprid and is known to appear in different environmental matrices. The product has been used as a media component during the isolation of 6-CNA degrading bacterial strain from imidacloprid-exposed soil samples.
Uses
6-Chloronicotinic acid is used as building block for different chemical synthesis. It is an intermediate for the synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAFV600E inhibitors, and novel DNA-gyrase B inhibitors.
Definition
ChEBI: 6-Chloronicotinic acid is a member of pyridines and an aromatic carboxylic acid.
General Description
6-Chloropyridine-3-carboxylic acid is a metabolite of the neonicotinoid pesticides, imidacloprid and acetamiprid and occurs in different environmental matrices.(3) It is widely used in agricultural crop protection, domestic insect control and environmental pest management.
Purification Methods
Purify it by recrystallisation from hot H2O and sublime it in a vacuum. [Pechmann & Welsch Chem Ber 17 2384 1884, Herz & Murty J Org Chem 26 122 1961, Beilstein 22/2 V 177.]
6-Chloronicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7378 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 811 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
View Lastest Price from 6-Chloronicotinic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-01-22 | 6-Chloronicotinic acid
5326-23-8
|
US $8.00-0.80 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-08-23 | 6-Chloronicotinic acid
5326-23-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2023-03-06 | 6-Chloronicotinic Acid
5326-23-8
|
US $10.70 / Kg/Bag | 10g | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD |
- 6-Chloronicotinic acid
5326-23-8
- US $8.00-0.80 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- 6-Chloronicotinic acid
5326-23-8
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- 6-Chloronicotinic Acid
5326-23-8
- US $10.70 / Kg/Bag
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
5326-23-8(6-Chloronicotinic acid)Related Search:
1of4