5,7-Dichloro-8-hydroxyquinaldine
- CAS No.
- 72-80-0
- Chemical Name:
- 5,7-Dichloro-8-hydroxyquinaldine
- Synonyms
- Quesil;Siogen;Siogene;Siogeno;Siosept;Afungil;Intensol;Saprosan;Siogenal;Siogenon
- CBNumber:
- CB4728346
- Molecular Formula:
- C10H7Cl2NO
- Molecular Weight:
- 228.07
- MDL Number:
- MFCD00023984
- MOL File:
- 72-80-0.mol
- MSDS File:
- SDS
| Melting point | 108-112 °C (dec.)(lit.) |
|---|---|
| Boiling point | 350.7±37.0 °C(Predicted) |
| Density | 1.3126 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO, Methaol (Slightly) |
| form | Solid |
| pka | 2.47±0.30(Predicted) |
| color | Dark Beige to Very Dark Beige |
| Water Solubility | Insoluble |
| Merck | 13,2209 |
| BRN | 156683 |
| CAS DataBase Reference | 72-80-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | D6VHC87LLS |
| ATC code | D08AH02,G01AC03,P01AA04,R02AA11 |
| NIST Chemistry Reference | Chlorquinaldol(72-80-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-36/37/38-23/24/25 | |||||||||
| Safety Statements | 26-36-36/37/39-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VC5600000 | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
5,7-Dichloro-8-hydroxyquinaldine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 130532 | 5,7-Dichloro-8-hydroxy-2-methylquinoline 98% | 72-80-0 | 10g | $62.2 | 2024-03-01 | Buy |
| Cayman Chemical | 29396 | Chlorquinaldol | 72-80-0 | 10g | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 29396 | Chlorquinaldol | 72-80-0 | 25g | $94 | 2024-03-01 | Buy |
| Cayman Chemical | 29396 | Chlorquinaldol | 72-80-0 | 50g | $177 | 2024-03-01 | Buy |
| TRC | D436823 | 5,7-Dichloro-8-hydroxy-2-methylquinoline | 72-80-0 | 500mg | $45 | 2021-12-16 | Buy |
5,7-Dichloro-8-hydroxyquinaldine Chemical Properties,Uses,Production
Chemical Properties
yellowish to beige-brown powder
Originator
Sterosan ,Geigy ,US ,1954
Uses
5,7-Dichloro-8-hydroxy-2-methylquinoline is an anti-infective agent.
Uses
Chlorquinaldol is a fungistat and antibacterial agent in topical pharmaceutical preparations (5,7-dichloro-2-methyl-8-quinolinol, Sterosan).
Uses
antiinfectant, antifungal
Definition
ChEBI: A monohydroxyquinoline that is quinolin-8-ol which is substituted by a methyl group at position 2 and by chlorine at positions 5 and 7. An antifungal and antibacterial, it was formerly used for topical treatment of skin conditions and vaginal infections.
Manufacturing Process
11.1 parts of 8-hydroxy-quinaldine are dissolved in 140 parts of formic acid.
Chlorine is introduced into this solution under cooling, until the increase in
weight corresponds to the required quantity of chlorine and a test of the
chlorination mixtures gives no more dyestuff formation with diazo-benzene in
an acetic acid solution
When the chlorination is complete, the reaction mixture is poured into 1,000
parts of water and treated with a dilute sodium bisulfite solution, until no
more reaction may be observed with starch potassium iodide paper. Thereby
the 5,7-dichloro-8-hydroxy-quinaldine separates out in form of a weakly
yellowish colored precipitate. The same is filtered off and thoroughly washed
with water.After drying, 15 parts of 5,7-dichloro-8-hydroxy-quinaldine melting at 111°C
to 112°C are obtained. When recrystallized from alcohol, the product is
obtained in voluminous, slightly yellowish needles having the melting point of
111.5°C to 112°C.
Therapeutic Function
Antibacterial
Purification Methods
Crystallise it from EtOH. [Beilstein 21/3 V 346.]
5,7-Dichloro-8-hydroxyquinaldine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 | 1047@dideu.com | China | 3459 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12468 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from 5,7-Dichloro-8-hydroxyquinaldine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-03-04 | 5,7-Dichloro-8-hydroxyquinaldine
72-80-0
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2022-02-19 | 5,7-dichloro-2-methylquinolin-8-ol
72-80-0
|
US $0.00 / KG | 1KG | 98.1% | 100 tons | Honest Joy Holdings Limited
|
|
 |
2021-10-29 | chlorquinaldol
72-80-0
|
US $0.00 / g | 100g | 99.99% | 10000 | Jiangsu Monade Biological Technology Co., Ltd. |
-
- 5,7-Dichloro-8-hydroxyquinaldine
72-80-0
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 5,7-dichloro-2-methylquinolin-8-ol
72-80-0
- US $0.00 / KG
- 98.1%
- Honest Joy Holdings Limited
-
- chlorquinaldol
72-80-0
- US $0.00 / g
- 99.99%
- Jiangsu Monade Biological Technology Co., Ltd.