ChemicalBook >> CAS DataBase List >>2,4-DICHLOROQUINOLINE

2,4-DICHLOROQUINOLINE

CAS No.
703-61-7
Chemical Name:
2,4-DICHLOROQUINOLINE
Synonyms
AURORA KA-3862;IFLAB-BB F1706-0118;2,4-DICHLOROQUINOLINE;Quinoline,2,4-dichloro-;2,4-Dichloroquinoline>2,4-Dichloroquinoline 98%;2-4-Dichloro-1-azanaphthalene;2,4-dichloroquinoline(SALTDATA: FREE)
CBNumber:
CB4757939
Molecular Formula:
C9H5Cl2N
Molecular Weight:
198.05
MDL Number:
MFCD00023939
MOL File:
703-61-7.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:39

2,4-DICHLOROQUINOLINE Properties

Melting point 52-54
Boiling point 282°C(lit.)
Density 1.4178 (rough estimate)
refractive index 1.6610 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Methanol
pka -1.10±0.50(Predicted)
form Solid
color White
λmax 305nm(MeOH)(lit.)
InChIKey QNBJYUUUYZVIJP-UHFFFAOYSA-N
CAS DataBase Reference 703-61-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06,GHS07
Signal word  Danger
Hazard statements  H301-H315-H318-H335-H319
Precautionary statements  P261-P280-P301+P310-P305+P351+P338-P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,T
Risk Statements  36/37/38-41-37/38-25
Safety Statements  26-36-45-39
RIDADR  2811
WGK Germany  3
Hazard Note  Irritant
HazardClass  6.1
PackingGroup 
HS Code  2933491090
NFPA 704
0
1 0

2,4-DICHLOROQUINOLINE price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D4452 2,4-Dichloroquinoline >98.0%(GC) 703-61-7 5g $82 2024-03-01 Buy
TCI Chemical D4452 2,4-Dichloroquinoline >98.0%(GC) 703-61-7 25g $244 2024-03-01 Buy
TRC D436225 2,4-Dichloroquinoline 703-61-7 1g $50 2021-12-16 Buy
Biosynth Carbosynth FD42902 2,4-Dichloroquinoline 703-61-7 1g $50 2021-12-16 Buy
Apolloscientific OR3822 2,4-Dichloroquinoline 98% 703-61-7 1g $22 2021-12-16 Buy
Product number Packaging Price Buy
D4452 5g $82 Buy
D4452 25g $244 Buy
D436225 1g $50 Buy
FD42902 1g $50 Buy
OR3822 1g $22 Buy

2,4-DICHLOROQUINOLINE Chemical Properties,Uses,Production

Uses

2,4-Dichloroquinoline is used in the synthesis of tRNA synthetase inhibitors with antibacterial activity against gram-positive bacteria. Also used in the preparation of arylquinolines displaying anthelmintic properties.

Synthesis

The synthesis of 2,4-dichloroquinoline is as follows:A suspension of quinoline-2,4-diol (150 g, 931 mmol) in POCl3 (975 mL, 10.4 mol) was stirred at reflux for 6 hr and the reaction mixture was concentrated. The residue was diluted with CHCl3 (500 mL) and the solution was poured into ice water. The aqueous layer was extracted with CHCl3 (three times). The combined organic layer was dried over MgSO4, filtrated, concentrated, and purified by flash chromatography (silica gel, 20% EtOAc in hexane) to give 2,4-dichloroquinoline (177 g, 96%) as a pale brown solid.  
synthesis of 2,4-DICHLOROQUINOLINE

2,4-DICHLOROQUINOLINE Preparation Products And Raw materials

Global( 211)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Shanghai Bojing Chemical Co.,Ltd.
+86-86-02137122233 +8613795318958 bj1@bj-chem.com China 298 55
Speranza Chemical Co., Ltd.
+86-86-075521030354 +8618688942810 sophieliu@speranzachem.com China 723 55
Win-Win Chemical CO., Limited
0086-577-64498589 sales@win-winchemical.com CHINA 998 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
BAYNOE CHEM CO.,LTD
+86-21-34783353 +8615000719740 baynoe@baynoe.com CHINA 934 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58

View Lastest Price from 2,4-DICHLOROQUINOLINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-DICHLOROQUINOLINE pictures 2022-09-27 2,4-DICHLOROQUINOLINE
703-61-7
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2,4-DICHLOROQUINOLINE pictures 2019-12-23 2,4-DICHLOROQUINOLINE
703-61-7
US $1.00 / g 1g 99% 1000KGS Career Henan Chemical Co
2,4-DICHLOROQUINOLINE AURORA KA-3862 IFLAB-BB F1706-0118 2,4-Dichloroquinoline 98% 2,4-dichloroquinoline(SALTDATA: FREE) 2-4-Dichloro-1-azanaphthalene Quinoline,2,4-dichloro- 2,4-Dichloroquinoline> 703-61-7 C9H5CI2N pharmacetical