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Exenatide acetate

CAS No.
141732-76-5
Chemical Name:
Exenatide acetate
Synonyms
AI315415;Exenatide;AI3 15415;AI3-15415;Extendin-4;Exenatide-d5;Unii-9p1872D4ol;EXENATIDE ACETATE;exendin-4, PC-DAC;Exennatide Acetate
CBNumber:
CB4789871
Molecular Formula:
C186H286N50O62S
Molecular Weight:
4244.60796
MDL Number:
MFCD08704781
MOL File:
141732-76-5.mol
MSDS File:
SDS
Last updated:2024-04-16 14:59:45

Exenatide acetate Properties

Melting point >209°C (dec.)
storage temp. Refrigerator, under inert atmosphere
solubility Acetonitrile (Slightly), Water (Slightly)
form Solid
color White to Off-White
Sequence H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
CAS DataBase Reference 141732-76-5(CAS DataBase Reference)
FDA UNII 9P1872D4OL
NCI Drug Dictionary exenatide
ATC code A10BJ01

Pharmacokinetic data

Excreted unchanged in urine Majority
Volume of distribution 28 Litres
Biological half-life 2.4 / 6

Exenatide acetate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E957300 ExenatideAcetate 141732-76-5 5mg $175 2021-12-16 Buy
ChemScene CS-0106996 Enfuvirtide(acetate) 98.91% 141732-76-5 25mg $228 2021-12-16 Buy
Biosynth Carbosynth FE23212 Exenatide acetate 141732-76-5 50mg $333 2021-12-16 Buy
Biorbyt Ltd orb611418 Exenatide 141732-76-5 5mg $345.1 2021-12-16 Buy
Biorbyt Ltd orb611417 Exenatide acetate 141732-76-5 5mg $345.1 2021-12-16 Buy
Product number Packaging Price Buy
E957300 5mg $175 Buy
CS-0106996 25mg $228 Buy
FE23212 50mg $333 Buy
orb611418 5mg $345.1 Buy
orb611417 5mg $345.1 Buy

Exenatide acetate Chemical Properties,Uses,Production

Chemical Properties

Exenatide acetate is White Solid

Uses

Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.

Uses

A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.

Clinical Use

39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.

Drug interactions

Potentially hazardous interactions with other drugs
Anticoagulants: possibly enhances anticoagulant effect of warfarin.
Other nephrotoxins: avoid concomitant use.

Metabolism

Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.

Exenatide acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 287)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
qingdao future trading Co., Ltd
+86-13335044410 +86-13335044410 cui56813@163.com China 110 58
Anhui Zhongda Biotechnology Co., Ltd
+8615689548120 linda@zhongda-biotech.com China 204 58
Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2944 58
Shanghai Chinqesen Biotechnology Co., Ltd.
+86-16628886292 +86-19521323435 sales2@qschem-pharma.com China 46 58
Dorne Chemical Technology co. LTD
+86-13583358881 +86-18560316533 Ethan@dornechem.com China 294 58
Shanghai Yunao International Trade Co., Ltd
+8617621705551 asdf@shanghaihg.cn China 265 58
Henan Tengmao Chemical Technology Co. LTD
+8615238638457 salesvip2@hntmhg.com China 415 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58

View Lastest Price from Exenatide acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Exenatide acetate pictures 2024-04-25 Exenatide acetate
141732-76-5
US $1.00 / g 1g 99% 100kg Dorne Chemical Technology co. LTD
Exenatide acetate pictures 2024-04-25 Exenatide acetate
141732-76-5
US $1.00-9.90 / g 1g 99% 100kg Wuhan Cell Pharmaceutical Co., Ltd
Exenatide Acetate pictures 2024-04-22 Exenatide Acetate
141732-76-5
US $30.00 / box 1box 98% 5000box hebei hongtan Biotechnology Co., Ltd
Exenatide His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2} EXENATIDE ACETATE(EXENDIN-4) His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 Exenatide Acettate EXENATIDE ACETATE ENFUVIRTIDE ACETATE Extendin-4 Unii-9p1872D4ol exendin-4, PC-DAC Exennatide Acetate Exenatide Acetate salt Exenatide-d5 Exenatide acetate USP/EP/BP Type 2 Diabetes Mellitus Exenatide Acetate Stimulate Weight Loss Peptide CAS:?141732-76-5 Exenatide Acetate D5Q: What is Exenatide Acetate D5 Q: What is the CAS Number of Exenatide Acetate D5 Q: What is the storage condition of Exenatide Acetate D5 Q: What are the applications of Exenatide Acetate D5 Exenatide acetateQ: What is Exenatide acetate Q: What is the CAS Number of Exenatide acetate Q: What is the storage condition of Exenatide acetate Q: What are the applications of Exenatide acetate AI3 15415 AI315415 AI3-15415 Exenatide impurities 141732-76-5 41758-74-9 C184H282N50O60SC2H4O2 Agonist Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals Peptide GLP 141732-76-5