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LICOCHALCONE-A

CAS No.
58749-22-7
Chemical Name:
LICOCHALCONE-A
Synonyms
CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%;Glycyrrhiza chalcone A;4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone
CBNumber:
CB5114580
Molecular Formula:
C21H22O4
Molecular Weight:
338.4
MDL Number:
MFCD01417903
MOL File:
58749-22-7.mol
MSDS File:
SDS
Last updated:2024-01-03 18:42:19

LICOCHALCONE-A Properties

Melting point 100°
Boiling point 532.6±50.0 °C(Predicted)
Density 1.171±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM)
DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM)
Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
pka 7.82±0.15(Predicted)
form Yellow solid
color Yellow-orange
BRN 4534154
InChIKey KAZSKMJFUPEHHW-DHZHZOJOSA-N
FDA UNII JTV5467968
NCI Drug Dictionary licochalcone A

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36/37
WGK Germany  3
RTECS  UB8755000
NFPA 704
0
3 0

LICOCHALCONE-A price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL80486 Licochalcone A phyproof? Reference Substance 58749-22-7 10MG $595 2024-03-01 Buy
Sigma-Aldrich 435800 Licochalcone-A, Synthetic 58749-22-7 10mg $111 2024-03-01 Buy
Sigma-Aldrich 435800 Licochalcone-A, Synthetic 58749-22-7 50mg $404 2024-03-01 Buy
Cayman Chemical 11853 Licochalcone A ≥95% 58749-22-7 5mg $49 2024-03-01 Buy
Cayman Chemical 11853 Licochalcone A ≥95% 58749-22-7 10mg $93 2024-03-01 Buy
Product number Packaging Price Buy
PHL80486 10MG $595 Buy
435800 10mg $111 Buy
435800 50mg $404 Buy
11853 5mg $49 Buy
11853 10mg $93 Buy

LICOCHALCONE-A Chemical Properties,Uses,Production

Uses

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

Definition

ChEBI: Licochalcone A is a member of chalcones.

General Description

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

LICOCHALCONE-A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 261)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618829768577 gao490372054@gamil.com China 1250 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+86-18580541567 +86-17782035140 sales@zhswyy.com China 338 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58

View Lastest Price from LICOCHALCONE-A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Licochalcone A pictures 2024-04-12 Licochalcone A
58749-22-7
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
LICOCHALCONE-A pictures 2024-04-07 LICOCHALCONE-A
58749-22-7
US $0.00-0.00 / kg 0.10000000149011612kg ≥98% 20tons Chongqing Zhihe Biopharmaceutical Co., Ltd.
Licochalcone A pictures 2023-11-30 Licochalcone A
58749-22-7
US $150.00 / KG 1KG 99%HPLC,USP Standard 800KGs ZhenYiBio Technology Inc
  • Licochalcone A pictures
  • Licochalcone A
    58749-22-7
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • LICOCHALCONE-A pictures
  • LICOCHALCONE-A
    58749-22-7
  • US $0.00-0.00 / kg
  • ≥98%
  • Chongqing Zhihe Biopharmaceutical Co., Ltd.
  • Licochalcone A pictures
  • Licochalcone A
    58749-22-7
  • US $150.00 / KG
  • 99%HPLC,USP Standard
  • ZhenYiBio Technology Inc
LICOCHALCONE-A (E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)- 7-Dimethoxycoumarin Licochalcone A, >=98% (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A Licochalcone A, >99% CS-919 Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one Licocgalcone-A (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one 4,4'-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one Glycyrrhiza chalcone A Licorice Chalcone A Licoricchalcone A 58749-22-7 The group of Liquorice sy chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract