ChemicalBook >> CAS DataBase List >>2-Hydroxy-5-methylpyridine
2-Hydroxy-5-methylpyridine
- CAS No.
- 1003-68-5
- Chemical Name:
- 2-Hydroxy-5-methylpyridine
- Synonyms
- 5-Methylpyridin-2(1H)-one;2(1H)-Pyridinone, 5-methyl-;5-methyl-2-pyridone;2-HYDROXY-5-PICOLINE;AKOS BBS-00002970;2-Hydroxy-5-methyL;5-METHYL-2-PYRIDINOL;6-HYDROXY-3-PICOLINE;5-METHYL-PYRIDIN-2-OL;2-Hydroxy-5-Piocoline
- CBNumber:
- CB5114924
- Molecular Formula:
- C6H7NO
- Molecular Weight:
- 109.13
- MDL Number:
- MFCD03092888
- MOL File:
- 1003-68-5.mol
- MSDS File:
- SDS
Last updated:2024-02-26 08:57:48
| Melting point | 183-187 °C (lit.) |
|---|---|
| Boiling point | 304.2±15.0 °C(Predicted) |
| Density | 1.053±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.43±0.10(Predicted) |
| color | Pale Yellow to Light Yellow |
| BRN | 107074 |
| InChI | InChI=1S/C6H7NO/c1-5-2-3-6(8)7-4-5/h2-4H,1H3,(H,7,8) |
| InChIKey | SOHMZGMHXUQHGE-UHFFFAOYSA-N |
| SMILES | C1(=O)NC=C(C)C=C1 |
| CAS DataBase Reference | 1003-68-5(CAS DataBase Reference) |
| FDA UNII | C173P2D70Y |
| NIST Chemistry Reference | 2(1H)-pyridinone, 5-methyl-(1003-68-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41-36/37/39 | |||||||||
| Safety Statements | 26-36-37 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
2-Hydroxy-5-methylpyridine price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T162647 | 5-METHYL-2(1H)-PYRIDINONE AldrichCPR | 1003-68-5 | 1MG | $139 | 2024-03-01 | Buy |
| Sigma-Aldrich | 593427 | 2-Hydroxy-5-methylpyridine 97% | 1003-68-5 | 1g | $53.8 | 2024-03-01 | Buy |
| TCI Chemical | H1167 | 2-Hydroxy-5-methylpyridine >98.0%(GC)(T) | 1003-68-5 | 5g | $22 | 2024-03-01 | Buy |
| TCI Chemical | H1167 | 2-Hydroxy-5-methylpyridine >98.0%(GC)(T) | 1003-68-5 | 25g | $69 | 2024-03-01 | Buy |
| Alfa Aesar | L19528 | 2-Hydroxy-5-methylpyridine, 98% | 1003-68-5 | 5g | $58.65 | 2024-03-01 | Buy |
2-Hydroxy-5-methylpyridine Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
2-Hydroxy-5-methylpyridine (cas# 1003-68-5) is a useful compound for organic synthesis. In particular it has been used for the diastereoselective preparation of cyclobutane-fused pyridinyl sulfonyl fluorides.
Definition
ChEBI: 5-Methyl-2-pyridinol is a member of methylpyridines.
Synthesis
3-cyano-6-hydroxypyridine and sodium lauryl sulfate were added to a mixed solvent of n-butanol and water. Subsequently, the temperature was raised to 50 °C., and sulfuric acid water obtained by dissolving 98% sulfuric acid in water was added dropwise at the temperature. After stirring for about 20 minutes, the mixture was cooled to room temperature, and 5% Pd / C was added. The system was replaced with hydrogen, and hydrogenation was carried out at atmospheric pressure for 6 hours. After the reaction was completed, the catalyst was removed by filtration, and the solution was washed with 10% sodium hydroxide aqueous solution. After partially neutralizing to H = 5 and extraction with n-butanol, a solution of crude 3-methyl-6-hydroxypyridine in butanol was obtained. When this solution was quantified by liquid chromatography, the pass-through rate was 99.2%, and the yield of 2-hydroxy-5-methylpyridine was 83%.
2-Hydroxy-5-methylpyridine Preparation Products And Raw materials
Global( 459)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Wuhan BJM Pharm Inc | +86-027-5234-1919 +8613545198479 | sales03@benjaminpharmchem.com | China | 671 | 58 |
| Nanjing Huazhou New Material Co., Ltd. | +8618913378169 | howard.wu@chinaredsun.com | China | 40 | 58 |
| Terma Medicare India Pvt.,Ltd | +8613916485955 | shivshanghai@yahoo.com | India | 132 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5964 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from 2-Hydroxy-5-methylpyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-06 | 2-Hydroxy-5-methylpyridine
1003-68-5
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-06-28 | 2-Hydroxy-5-methylpyridine
1003-68-5
|
US $9.00 / KG | 1KG | 99.9 | 1 ton | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2023-04-27 | 2-Hydroxy-5-methylpyridine
1003-68-5
|
US $70.00 / kg | 1kg | 99% | 100 tons | Hebei Duling International Trade Co. LTD |
-
- 2-Hydroxy-5-methylpyridine
1003-68-5
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- 2-Hydroxy-5-methylpyridine
1003-68-5
- US $9.00 / KG
- 99.9
- Hebei Guanlang Biotechnology Co,.LTD
-
- 2-Hydroxy-5-methylpyridine
1003-68-5
- US $70.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
1003-68-5(2-Hydroxy-5-methylpyridine)Related Search:
6-HYDROXY-3-PICOLINE
5-METHYL-2(1H)PYPRIDINONE
5-METHYL-2(1H)-PYRIDINONE
5-METHYL-2(1H)PYRIDONE
5-METHYL-2-PYRIDINOL
5-METHYL-PYRIDIN-2-OL
5-METHYLPYRIDINE-2-ONE
AKOS BBS-00002970
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5-Methyl-1,2-dihydropyridine-2-one
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5-Methyl-2(1H)-pyridinone
Hydroxy-5-Methylpyrid
5-methyl-(1H)pyridinone
Pirfenidone Impurity 2（Pirfenidone EP Impurity B）
2-Hydroxy-5-methyL
(91914-06-6) 2-hydroxy-5-methylpyridine
Perfenidone Impurity 1
5-Methylpyridin-2(1H)-one 98%
2-Hydroxy-5-methylpyridine>
2-Hydro-5-methylpyridine
2-Hydroxy-5-methylpyridine ISO 9001：2015 REACH
Big Discount Purity 99% 2-Hydroxy-5-Methylpyridine CAS 1003-68-5 with Best Quality
5-methyl-1,2-dihydropyridin-2-one
5-Methylpyridin-2(1H)-one
2(1H)-Pyridinone, 5-methyl-
5-methyl-2-pyridone
2-HYDROXY-5-PICOLINE
2-HYDROXY-5-METHYLPYRIDINEE
Pirfenidone EP Impurity B
5-methylpyridin-2(1H)-one
1003-68-5
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