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N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

CAS No.
42267-27-6
Chemical Name:
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
Synonyms
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride;Lys-NCA;L-Lys(TFA)-NCA;Lysine-TFA-NCA;Creatinine Impurity 4;Meloxicam Impurity 25;L-LYS(TFA)-NCA(42267-27-6);e-Trifluoroacetyl-Lysine, NCA;-N-(4-(2,5-Dioxooxazolidin-4-yl);N-trifluoroacetyl lysine N-carboxyanhydride
CBNumber:
CB51456876
Molecular Formula:
C9H11F3N2O4
Molecular Weight:
268.19
MDL Number:
MFCD11046652
MOL File:
42267-27-6.mol
MSDS File:
SDS
Last updated:2024-01-19 18:04:22

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Properties

Melting point 92-93℃ (DEC.)
Density 1.377
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Ethyl Acetate (Slightly)
pka 9.27±0.40(Predicted)
form Solid
color White to Off-White
InChI InChI=1S/C9H11F3N2O4/c10-9(11,12)7(16)13-4-2-1-3-5-6(15)18-8(17)14-5/h5H,1-4H2,(H,13,16)(H,14,17)/t5-/m0/s1
InChIKey KWNIHCJDDYRQFW-YFKPBYRVSA-N
SMILES C(NCCCC[C@H]1C(=O)OC(=O)N1)(=O)C(F)(F)F

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS05
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2933.79.8500

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D5600 (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide 42267-27-6 1G $41 2024-03-01 Buy
TCI Chemical D5600 (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide 42267-27-6 5G $187 2024-03-01 Buy
TRC T788530 N6-Trifluoroacetyl-L-lysineN-Carboxyanhydride 42267-27-6 1g $90 2021-12-16 Buy
TRC T788530 N6-Trifluoroacetyl-L-lysineN-Carboxyanhydride 42267-27-6 2g $130 2021-12-16 Buy
TRC T788530 N6-Trifluoroacetyl-L-lysineN-Carboxyanhydride 42267-27-6 10g $325 2021-12-16 Buy
Product number Packaging Price Buy
D5600 1G $41 Buy
D5600 5G $187 Buy
T788530 1g $90 Buy
T788530 2g $130 Buy
T788530 10g $325 Buy

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Chemical Properties,Uses,Production

Description

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride is a N6-trifluoroacetylated lysine derivative that is used in the synthesis of peptides. It is a racemic mixture of L and D forms, which is hydrolyzed to form L-glutamic acid, NH4Cl, and CO2. N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride has been shown to be useful in the formation of bonds between amino acids, such as lysine and dipeptides. The compound is also used for the protection of lysine against oxidation during peptide synthesis.

Chemical Properties

White to Off-White Solid

Uses

Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers. ?DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.

Uses

L-Lys(Tfa)-NCA (N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride) can be used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers.

112139-31-8
42267-27-6
Synthesis of N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride from L-Lysine, N2-(chlorocarbonyl)-N6-(trifluoroacetyl)- (9CI)

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 148)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8618980456393 daisy@enlaibio.com China 1369 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Sichuan Jiaying Lai Technology Co.,LTD
18716376478 ycling@enlaibio.com CHINA 302 58
Changzhou Carman Chemical Co., Ltd.
15061933924 CHINA 514 58

View Lastest Price from N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Lys(tfa)-NCA pictures 2024-04-25 L-Lys(tfa)-NCA
42267-27-6
US $0.00-0.00 / kg 1kg 99%+ 1T Sichuan HongRi Pharma-Tech Co.,Ltd
L-Lys(tfa)-NCA pictures 2020-01-06 L-Lys(tfa)-NCA
42267-27-6
US $1.00 / g 10g 98% 100kg Sichuan Jiaying Lai Technology Co.,LTD
N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide pictures 2019-09-05 N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide
42267-27-6
US $1.80-3.60 / KG 1KG 99% 88KG Career Henan Chemical Co
  • L-Lys(tfa)-NCA pictures
  • L-Lys(tfa)-NCA
    42267-27-6
  • US $0.00-0.00 / kg
  • 99%+
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • L-Lys(tfa)-NCA pictures
  • L-Lys(tfa)-NCA
    42267-27-6
  • US $1.00 / g
  • 98%
  • Sichuan Jiaying Lai Technology Co.,LTD
N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide e-Trifluoroacetyl-Lysine, NCA N-Trifluoroacetyl-L-lysine N-carboxyanhydride N-(4-(2,5-Dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluoroacetamide (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetaMide N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetaMide AcetaMide,N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro- N-[3-[(4S)-2,5-dioxooxazolidin-4-yl]propyl]-2,2,2-trifluoro-acetaMide N-trifluoroacetyl lysine N-carboxyanhydride 4-[(4S)-2,5-DIOXOOXAZOLIDIN-4-YL]BUTYL]-2,2,2-TRIFLUORO-ACETAMIDE (S)-N-(4-(2,5-Dioxooxazolidin-4-yl)-butyl)-2,2,2-trifluoroacetamide L-Lys(TFA)-NCA Lys-NCA -N-(4-(2,5-Dioxooxazolidin-4-yl) L-Lysine-N-Trifluoroacetyl-N-Carboxyanhydride L-LYS(TFA)-NCA(42267-27-6) Lysine-TFA-NCA N-[4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl]-2,2,2-trifluoroacetamide Nepsilon-Trifluoroacetyl-Nalpha-carboxy-L-lysine Anhydride Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifl... N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Creatinine Impurity 4 Meloxicam Impurity 25 N6-(Trifluoroacetyl)-N2-carboxy-L-Lysine anhydride Ne-trifluoroacetyl L-lysine intracyclic anhydride 42267-27-6 C9H11F3N2O4 AMINOACIDS DERIVATIVES Amino Acids & Derivatives Aromatics Chiral Reagents Heterocycles