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Succinic anhydride

CAS No.
108-30-5
Chemical Name:
Succinic anhydride
Synonyms
SAN;succinic;SAA;DIHYDRO-2,5-FURANDIONE;SUCCINIC ACID ANHYDRIDE;SAA1;Dihydro-furan-2,5-dione;BUTANEDIOIC ANHYDRIDE;Bernsteinsaure-anhydrid;Serum amyloid A protein
CBNumber:
CB5166246
Molecular Formula:
C4H4O3
Molecular Weight:
100.07
MDL Number:
MFCD00005525
MOL File:
108-30-5.mol
MSDS File:
SDS
Last updated:2024-03-27 13:09:27

Succinic anhydride Properties

Melting point 118-120 °C (lit.)
Boiling point 261 °C (lit.)
Density 1,572 g/cm3
vapor density 3.5 (vs air)
vapor pressure 1 mm Hg ( 92 °C)
refractive index 1.4688 (estimate)
Flash point 157°C
storage temp. Store below +30°C.
solubility 62.9g/l Hydrolysis
form Solid
pka 4.67[at 20 ℃]
color White to Off-White
Specific Gravity 1.2340 (20℃)
PH 2.7 (10g/l, H2O)
Water Solubility <0.1 g/100 mL at 21 ºC (decomposes)
Sensitive Moisture Sensitive
Merck 14,8870
BRN 108441
Stability Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture.
InChIKey RINCXYDBBGOEEQ-UHFFFAOYSA-N
LogP 2.44 at 40℃
Substances Added to Food (formerly EAFUS) SUCCINIC ANHYDRIDE
CAS DataBase Reference 108-30-5(CAS DataBase Reference)
EWG's Food Scores 2
FDA UNII 6RF4O17Z8J
IARC 3 (Vol. 15, Sup 7) 1987
NIST Chemistry Reference 2,5-Furandione, dihydro-(108-30-5)
EPA Substance Registry System Succinic anhydride (108-30-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Warning
Hazard statements  H290
Precautionary statements  P234-P390
Hazard Codes  Xi,Xn
Risk Statements  36/37-22
Safety Statements  25-46
RIDADR  UN 3261 8 / PGII
WGK Germany  1
RTECS  WN0875000
21
Autoignition Temperature 480 °C
TSCA  Yes
HS Code  29171990
Toxicity LD50 orally in Rabbit: 1510 mg/kg
NFPA 704
0
2 0

Succinic anhydride price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.00683 Succinic anhydride for synthesis 108-30-5 100g $40 2024-03-01 Buy
Sigma-Aldrich 8.00683 Succinic anhydride for synthesis 108-30-5 500g $55.5 2024-03-01 Buy
Sigma-Aldrich 8.00683 Succinic anhydride for synthesis 108-30-5 1kg $80.7 2024-03-01 Buy
Sigma-Aldrich 8.00683 Succinic anhydride for synthesis 108-30-5 50kg $1690 2024-03-01 Buy
Sigma-Aldrich 239690 Succinic anhydride ≥99% (GC) 108-30-5 50g $54.2 2024-03-01 Buy
Product number Packaging Price Buy
8.00683 100g $40 Buy
8.00683 500g $55.5 Buy
8.00683 1kg $80.7 Buy
8.00683 50kg $1690 Buy
239690 50g $54.2 Buy

Succinic anhydride Chemical Properties,Uses,Production

Description

Succinic anhydride, also called di hydro - 2,5- furandione , is an organic compound with the molecular formula C4H4O3.This colorless solid is the acid anhydride of succinic acid.

Chemical Properties

fine white crystalline solid

Chemical Properties

Succinic anhydride is an odourless, colourless needle-like or white crystalline solid natural product. Molecular formula C4H4O3, molecular weight 100.07 g/mol, relative density 1.503, melting point 237 °F. 239 °F at 5 mmHg, 239 °F at 198 °F and 1 mmHg. Soluble in chloroform, carbon tetrachloride, and ethanol; very slightly soluble in ether and water (insoluble in water). Moderately toxic and irritating, emits pungent and irritating fumes when heated to decomposition.

Uses

Succinic Anhydride is an acidulant that hydrolyzes very slowly to succinic acid in water. it has thermal stability and a low melting point of 118°c which permits it to be used in products at compara- tively low temperatures. it is used as a leavening acidulant for bak- ing powder.

Uses

It was used in the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.It was also used in preparing functionalized oxide surfaces on a chip.

Uses

Succinic Anhydride is a useful compound in the paper manufacturing process.

Preparation

A solution of succinic acid (500 mg, 42 mmol) and triethylamine (1.23 mL, 42 mmol) in anhydrous THF (120 mL) was allowed to react with triphosgene (42 mg, 7.0 mmol) at ice-water temperature for 10 min. The reaction mixture was subsequently stirred for a further 15 min at room temperature. The solution was then filtered, and the filtrate was concentrated to dryness. The residue was crystallized from ethyl acetate to afford the desired product as white crystals (370 mg, 85%).

Production Methods

The compound is produced from succinic anhydride and hydrogen peroxide . This material must be stabilized by using a dehydrating agent such as disodium sulfate or magnesium sulfate.

Application

Alkyl succinic anhydride (ASA) is used as a sizing agent or wet strength additive in paper production.

Definition

ChEBI: Succinic anhydride is a cyclic dicarboxylic anhydride and a tetrahydrofurandione. It is functionally related to a succinic acid.

Synthesis Reference(s)

Synthetic Communications, 23, p. 419, 1993 DOI: 10.1080/00397919308009796

General Description

Succinic anhydride is a cyclic anhydride of succinic acid with a five-membered ring. It is widely used in the manufacture of polymeric materials, pharmaceuticals, agrochemicals, dyes, surface-active agents, and organic flame-retardant materials. It also finds application as a cross-linking agent in ion-exchange membranes and a curing agent for epoxy resins.

General Description

Colorless needles or white crystalline solid. Melting point 237°F. Sublimes at 239°F at 5 mm Hg pressure; and at 198°F and 1 mm Hg pressure. Moderately toxic and an irritant.

Air & Water Reactions

Reacts slowly with water. Insoluble in water.

Reactivity Profile

Succinic anhydride reacts exothermically with water. Reactions are usually slow, but might become violent if local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.

Fire Hazard

Flash point data for Succinic anhydride are not available, however, Succinic anhydride is probably combustible.

Flammability and Explosibility

Not classified

Materials Uses

Succinic anhydride can be used:
(1) In the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.
(2) In preparing functionalized oxide surfaces on a chip.
(3) As a starting material to synthesize polyesters in presence of a metal triflate as a catalyst.
(4) As a cross-linking agent to enhance the mechanicalproperties and antimicrobial activities of zein films.

Safety Profile

Experimental teratogenic effects. Moderately toxic by ingestion. A severe eye irritant. Mutation data reported. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also ANHYDRIDES.

Purification Methods

Crystallise the anhydride from redistilled acetic anhydride or CHCl3, then filter, wash with diethyl ether and dry it in a vacuum. [Beilstein 17 H 606, 17 V 6.]

108-31-6
108-30-5
Synthesis of Succinic anhydride from CIS-BUTENEDIOIC ANHYDRIDE
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View Lastest Price from Succinic anhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Succinic anhydride pictures 2024-03-29 Succinic anhydride
108-30-5
US $1.00 / kg 1kg ≥99% 2000mt/year Jinan Finer Chemical Co., Ltd
Succinic anhydride pictures 2024-03-27 Succinic anhydride
108-30-5
US $0.00-0.00 / kg 1kg 99% 50000kg Hebei Yibangte Import and Export Co. , Ltd.
Succinic anhydride pictures 2024-01-18 Succinic anhydride
108-30-5
US $6.00-0.60 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • Succinic anhydride pictures
  • Succinic anhydride
    108-30-5
  • US $0.00-0.00 / kg
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  • Hebei Yibangte Import and Export Co. , Ltd.
2,5(3H,4H)-Furandione 5-Furandione,dihydro-2 bernsteinsaureanhydrid dihydro-5-furandione NCI-C55696 Oxolan-2,5-dione rikacidsa Succinyl anhydride succinylanhydride tetrahydro-2,5-furandione AURORA KA-669 BUTANEDIOIC ACID ANHYDRIDE Dihydro-2,5-diketotetrahydrofuran AKOS BBS-00004273 Dihydrofuran-2,5-dione, 2,5-Dioxotetrahydrofuran 2,5-FURANDIONE, DIHYDRO 2,5-DIOXOTETRAHYDROFURAN 2,5-DIKETOTETRAHYDROFURAN SUCCINIC ACID ANDHYDRIDE SUCCINYL OXIDE SUCCINIC ANHYDRIDE Tetrahydro-2,5-dioxofuran Amyloid fibril protein AA Amyloid protein A SAA2 Human Serum Amyloid A ELISA Kit Succinic anhydride >=99% (GC) Succinic anhydride≥ 99% (Assay) Butanedioc anhydride~Dihydro-2,5-furandione SUCCINIC ANHYDRIED SUCCINIC ANHYDRIDE 99% SUCCINIC ANHYDRIDE, 99+% Succinic Acid Anhydride, 99+% SuccinimideForSynthesis SuccinicAnhydride,~93% SuccinicAnhydrideForSynthesis butanedioc anhydride SUCCINICANHYDRIDE,REAGENT SUCCINIC ANHYDRIDE extrapure Succinic anhydride, 99% 1KG Succinic anhydride, 99% 50GR 3,4-Dihydro-2,5-furandione 3,4-Dihydrofuran-2,5-dione SAA Succinic acid anhydride Bernsteinsaure anhydride NSC 8518 Succinic Anhydridc Succinic Anhydride > 108-30-8? Recombinant Human SAA1 Protein, His Tag Recombinant Human SAA1/SAA Protein, His Tag Recombinant Human Serum Amyloid A1/SAA1 Protein, His Tag Succinic anhydride ISO 9001:2015 REACH High Quality Golden Supplier Succinic Anhydride CAS 108-30-5 Succinic Anhydride LR Succinic Anhydride extrapure, 99.5% Bernsteinsaure-anhydrid Dihydro-furan-2,5-dione