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CYTOCHALASIN E

CAS No.
36011-19-5
Chemical Name:
CYTOCHALASIN E
Synonyms
CYTOCHALACINE;CYTOCHALICINE;CYTOCHALASIN E;CYTOCHALASIN 3;CYTOCHALASIN E(RG);CYTOCHALASIN E USP/EP/BP;LAJXCUNOQSHRJO-DXUWGLIISA-N;CYTOCHALASIN E(RG) Please Call;CYTOCHALASIN E, ASPERGILLUS CLAVATUS;CYTOCHALASIN E FROM ASPERGILLUSCLAVATUS
CBNumber:
CB5192252
Molecular Formula:
C28H33NO7
Molecular Weight:
495.56
MDL Number:
MFCD00005178
MOL File:
36011-19-5.mol
MSDS File:
SDS
Last updated:2023-07-14 17:33:58

CYTOCHALASIN E Properties

Melting point 206 °C
Boiling point 587.59°C (rough estimate)
Density 1.2415 (rough estimate)
refractive index 1.6290 (estimate)
storage temp. -20°C
solubility DMF: 11 mg/ml; DMF:PBS (pH7.2) (1:30): 0.03 mg/ml; DMSO: 10 mg/ml; Ethanol: 2 mg/ml
form White solid.
pka 11.22±0.70(Predicted)
BRN 1096975
LogP 1.920 (est)
EWG's Food Scores 1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H300-H310-H330-H361
Precautionary statements  P260-P264-P280-P284-P301+P310-P302+P350
Hazard Codes  T+,T
Risk Statements  26/27/28-63
Safety Statements  28-36/37-45
RIDADR  UN 1544 6.1/PG 2
WGK Germany  3
RTECS  HA5360000
10
HazardClass  6.1(a)
PackingGroup  I
HS Code  29349990
NFPA 704
0
2 0

CYTOCHALASIN E price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C2149 Cytochalasin E from Aspergillus clavatus 36011-19-5 1mg $275 2022-05-15 Buy
Sigma-Aldrich C2149 Cytochalasin E from Aspergillus clavatus 36011-19-5 5mg $1080 2022-05-15 Buy
Cayman Chemical 11331 Cytochalasin E ≥98% 36011-19-5 1mg $67 2024-03-01 Buy
Cayman Chemical 11331 Cytochalasin E ≥98% 36011-19-5 5mg $266 2024-03-01 Buy
Cayman Chemical 11331 Cytochalasin E ≥98% 36011-19-5 10mg $498 2024-03-01 Buy
Product number Packaging Price Buy
C2149 1mg $275 Buy
C2149 5mg $1080 Buy
11331 1mg $67 Buy
11331 5mg $266 Buy
11331 10mg $498 Buy

CYTOCHALASIN E Chemical Properties,Uses,Production

Description

The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin E is an epoxide-containing analog of cytochalasin B which potently and selectively inhibits the growth of endothelial cells (IC50 < 1 nM), impairing angiogenesis and tumor growth. This cytochalasin does not inhibit glucose transport or HIV-1 protease activity.

Chemical Properties

white powder

Uses

Cytochalasin E has been used as:

  • a toxin to study its effects on avocado plants
  • a component of the incubating medium in feline junctional adhesion molecule 1 (fJAM-1) expression assay
  • an inhibitor of actin polymerization to study its effects on mitochondria uptake by mice endothelial cells

Uses

Cytochalasin E is a fungal metabolite which has been shown to exhibit antimicrobial and antibacterial effects. Cytochalasin E is a microfilament inhibitor enhancing the low-affinity Fc epsilon receptor (CD23) expression.

Uses

Cytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. Despite the common mode of action, there is evidence that individual members display diverse selectivity. Specifically, cytochalasin E acts as an angiogenesis inhibitor and, unlike other cytochalasins, does not inhibit glucose transport.

Definition

ChEBI: A natural product found in Arthrinium sacchari.

Biochem/physiol Actions

Cytochalasin E is an epoxide that exhibits anti-proliferative activity in endothelial cells in vitro. It also participates in inhibiting tumor growth and angiogenesis in vivo. Cytochalasin E also possesses antimicrobial and antiviral properties.

CYTOCHALASIN E Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 93)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 3586 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9358 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29271 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33349 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4647 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80

View Lastest Price from CYTOCHALASIN E manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CYTOCHALASIN E USP/EP/BP pictures 2021-06-24 CYTOCHALASIN E USP/EP/BP
36011-19-5
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Cytochalasin E  pictures 2020-05-08 Cytochalasin E
36011-19-5
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
(7S,13E,16S,18R,19E)-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-dioxa[13]cytochalasa-13,19-diene-1,17,22-trione [7β,13E,16S,18R,19E]-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-dioxa[13]cytochalasa-13,19-diene-1,17,22-trione (7s,13e,16s,18r,19e)-18-dimethyl-10-phenyl 21,23-dioxa(13)cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16, 6,7-epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-[13]cytochalas-13,19-die CYTOCHALASIN 3 CYTOCHALASIN E CYTOCHALASIN E, ASPERGILLUS CLAVATUS 1,3Dioxacyclotridecino4,5-doxirenofisoindole-5,10,12(4H,6H)-trione, 3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-, (1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)- CYTOCHALASIN E(RG) CYTOCHALASIN E(RG) Please Call CYTOCHALACINE CYTOCHALICINE 21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione, 6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E)- CYTOCHALASIN E FROM ASPERGILLUSCLAVATUS CYTOCHALASIN E FROM ASPERGILLUS & LAJXCUNOQSHRJO-DXUWGLIISA-N Cytochalasin E, 99%, from Aspergillus clavatus CYTOCHALASIN E USP/EP/BP 36011-19-5 C28H33N1O7 C28H33NO7 Cell Biology Cell Signaling and Neuroscience Actin Inhibitors and Probes BioChemical Cytoskeleton and Extracellular Matrix antibiotic Actin Inhibitors and ProbesCell Signaling and Neuroscience Cell Signaling and Neuroscience Cytoskeleton and Extracellular Matrix Mold Toxins and Venoms