4-Hydroxybenzylamine
- CAS No.
- 696-60-6
- Chemical Name:
- 4-Hydroxybenzylamine
- Synonyms
- 4-(AMINOMETHYL)PHENOL;4-HOBA;AI320348;AI3 20348;AI3-20348;NSC 125720;RARECHEM AL BW 0048;4-HYDROXYBENZYLAMINE;Bisoprolol Impurity 26;Phenol, 4-(aminomethyl)-
- CBNumber:
- CB5207547
- Molecular Formula:
- C7H9NO
- Molecular Weight:
- 123.15
- MDL Number:
- MFCD00870499
- MOL File:
- 696-60-6.mol
- MSDS File:
- SDS
| Melting point | 123-128 °C |
|---|---|
| Boiling point | 262.4±15.0 °C(Predicted) |
| Density | 1.141±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Water (Slightly, Heated) |
| form | Powder |
| pka | 8.93±0.26(Predicted) |
| color | Off-white to pale yellow |
| InChIKey | RQJDUEKERVZLLU-UHFFFAOYSA-N |
| LogP | 0.350 (est) |
| CAS DataBase Reference | 696-60-6(CAS DataBase Reference) |
| FDA UNII | 7J7F85B7BI |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 34-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-24/25 | |||||||||
| RIDADR | 2735 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, CORROSIVE | |||||||||
| HS Code | 29214990 | |||||||||
| NFPA 704 |
|
4-Hydroxybenzylamine price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 776505 | 4-Hydroxybenzylamine | 696-60-6 | 5g | $69.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 776505 | 4-Hydroxybenzylamine | 696-60-6 | 25g | $102 | 2024-03-01 | Buy |
| TCI Chemical | A2305 | 4-(Aminomethyl)phenol >98.0%(GC)(T) | 696-60-6 | 1g | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 25398 | 4-HOBA | 696-60-6 | 10g | $53 | 2024-03-01 | Buy |
| Cayman Chemical | 25398 | 4-HOBA | 696-60-6 | 25g | $82 | 2024-03-01 | Buy |
4-Hydroxybenzylamine Chemical Properties,Uses,Production
Description
4-HOBA is an isomer of the isoketal scavenger 2-HOBA that has reduced efficacy as an isoketal scavenger. Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II in mice. 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.
Chemical Properties
4-Hydroxybenzylamine, also known as tyramine and p-hydroxyphenethylamine, is a white or off-white or light green solid. Tyramine, a compound originally isolated from ergot alkaloids and decomposed animal tissues, is an important synthetic drug intermediate.
Uses
4-Hydroxybenzylamine (cas# 696-60-6) is a compound useful in organic synthesis.
Definition
ChEBI: 4-Hydroxybenzylamine is an aromatic amine.
Preparation
Synthesis of 4-Hydroxybenzylamine:Ammonia is passed into 500 ml of ethanol at 10° C. until saturation is reached, 122.1 g=1 mole of p-hydroxybenzaldehyde, 20 g of Raney nickel and 0.1 ml of concentrated sulfuric acid are added and the mixture is stirred in an autoclave for 6 hours at room temperature and under a hydrogen pressure of 100 atmospheres. After releasing the pressure, the catalyst is filtered off and the filtrate is boiled up with active charcoal, filtered and concentrated. The residue is recrystallized from a mixture of ethanol and ether. This gives 104 g (85% of theory), melting point: 104° C.
Literature source US04391805
target
GABA Receptor
4-Hydroxybenzylamine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Yushan Wanfang Biotechnology Co., Ltd. | +86-025-84918180 +86-18014482516 | 3552541679@qq.com | China | 1001 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
View Lastest Price from 4-Hydroxybenzylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-06 | 4-Hydroxybenzylamine
696-60-6
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-03-06 | 4-Hydroxybenzylamine
696-60-6
|
US $1.90 / KG | 1KG | 99% | 10 ton | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2021-07-13 | 4-Hydroxybenzylamine
696-60-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 4-Hydroxybenzylamine
696-60-6
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- 4-Hydroxybenzylamine
696-60-6
- US $1.90 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- 4-Hydroxybenzylamine
696-60-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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