1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone
- CAS No.
- 6384-73-2
- Chemical Name:
- 1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone
- Synonyms
- Samandaridine;1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone;2,5-Epoxyfuro[3'',2'':3',4']cyclopenta[1',2':5,6]naphth[1,2-d]azepin-9(1H)-one, octadecahydro-5a,7a-dimethyl-, (2S,5R,5aS,5bS,7aS,7bR,10aS,11aS,11bS,13aR)-
- CBNumber:
- CB52228272
- Molecular Formula:
- C21H31NO3
- Molecular Weight:
- 345.48
- MDL Number:
- MOL File:
- 6384-73-2.mol
Last updated:2023-07-12 17:06:21
| Melting point | 287-8°C |
|---|---|
| Boiling point | 498.9±45.0 °C(Predicted) |
| Density | 1.153±0.06 g/cm3(Predicted) |
| pka | 8.69±0.60(Predicted) |
| FDA UNII | WCB49WL3GW |
1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone Chemical Properties,Uses,Production
Description
A hex acyclic alkaloid present in the skin secretions of various species of Salamandra (salamanders), the base yields a crystalline hydrochloride, m.p. 343°C; [α]24578 + 14.1° and a hydrobromide which crystallizes from MeOH with solvent of crystallization, m.p. 346°C. The structure has been determined from the infrared, NMR and mass spectra.
References
Schopf, Koch., Annalen, 552,41 (1942)
Habermehl., Chem. Ber., 96, 143,840 (1963)
1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone Preparation Products And Raw materials
Raw materials
Preparation Products
1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone
Samandaridine
2,5-Epoxyfuro[3'',2'':3',4']cyclopenta[1',2':5,6]naphth[1,2-d]azepin-9(1H)-one, octadecahydro-5a,7a-dimethyl-, (2S,5R,5aS,5bS,7aS,7bR,10aS,11aS,11bS,13aR)-
6384-73-2